SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q2XPP3

- Q2XPP3_HUMAN

UniProt

Q2XPP3 - Q2XPP3_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name: Type II 3a-hydroxysteroid dehydrogenase variant
Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei55 – 551Proton donor By similarityUniRule annotation

GO - Molecular functioni

  1. oxidoreductase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Type II 3a-hydroxysteroid dehydrogenase variantImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    PTM / Processingi

    Proteomic databases

    PRIDEiQ2XPP3.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2XPP3.
    SMRiQ2XPP3. Positions 6-321.

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG000020.

    Family and domain databases

    Gene3Di3.20.20.100. 1 hit.
    InterProiIPR001395. Aldo/ket_red.
    IPR018170. Aldo/ket_reductase_CS.
    IPR020471. Aldo/keto_reductase_subgr.
    IPR023210. NADP_OxRdtase_dom.
    [Graphical view]
    PANTHERiPTHR11732. PTHR11732. 1 hit.
    PfamiPF00248. Aldo_ket_red. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000097. AKR. 1 hit.
    PRINTSiPR00069. ALDKETRDTASE.
    SUPFAMiSSF51430. SSF51430. 1 hit.
    PROSITEiPS00798. ALDOKETO_REDUCTASE_1. 1 hit.
    PS00062. ALDOKETO_REDUCTASE_2. 1 hit.
    PS00063. ALDOKETO_REDUCTASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2XPP3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDSKHQCVKL NDGHFMPVLG FGTYAPAEVP KSKALEATKL AIEAGFRHID    50
    SAHLYNNEEQ VGLAVRSKIA DGSVKREDIF YTSKLWCNSH RPELVRPALE 100
    RSLKKAQLDY VDLYLIHSPM SLKPGEELSP TDENGKVIFD IVDLCTTWEA 150
    MEKCKDAGLA KSIGVSNFNR RQLEMILNKP GLKYKPVCNQ VECHPYFNRS 200
    KLLDFCKSKD IVLVAYSALG SQRDKRWVDP NSPVLLEDPV LCALAKKHKR 250
    TPALIALRYQ LQRGVVVLAK SYNEQRIRQN VQVFEFQLTA EDMKAIDGLD 300
    RNLHYFNSDS FASHPNYPYS DEY 323
    Length:323
    Mass (Da):36,768
    Last modified:December 20, 2005 - v1
    Checksum:i23D42E6CB3C48ACF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ269985 mRNA. Translation: ABB76132.1.
    UniGeneiHs.78183.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ269985 mRNA. Translation: ABB76132.1 .
    UniGenei Hs.78183.

    3D structure databases

    ProteinModelPortali Q2XPP3.
    SMRi Q2XPP3. Positions 6-321.
    ModBasei Search...

    Proteomic databases

    PRIDEi Q2XPP3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG000020.

    Family and domain databases

    Gene3Di 3.20.20.100. 1 hit.
    InterProi IPR001395. Aldo/ket_red.
    IPR018170. Aldo/ket_reductase_CS.
    IPR020471. Aldo/keto_reductase_subgr.
    IPR023210. NADP_OxRdtase_dom.
    [Graphical view ]
    PANTHERi PTHR11732. PTHR11732. 1 hit.
    Pfami PF00248. Aldo_ket_red. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000097. AKR. 1 hit.
    PRINTSi PR00069. ALDKETRDTASE.
    SUPFAMi SSF51430. SSF51430. 1 hit.
    PROSITEi PS00798. ALDOKETO_REDUCTASE_1. 1 hit.
    PS00062. ALDOKETO_REDUCTASE_2. 1 hit.
    PS00063. ALDOKETO_REDUCTASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Overexpression of dihydrodiol dehydrogenase 2, AKR1C2, in bladder cancer patients from high-risk region of black foot disease in Taiwan."
      Chow K.-C.
      Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: Bladder cancerImported.

    Entry informationi

    Entry nameiQ2XPP3_HUMAN
    AccessioniPrimary (citable) accession number: Q2XPP3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 20, 2005
    Last sequence update: December 20, 2005
    Last modified: June 11, 2014
    This is version 45 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Similar proteinsi