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Q2XPP3 (Q2XPP3_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
OrganismHomo sapiens (Human) EMBL ABB76132.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length323 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

Ontologies

Gene Ontology (GO)
   Molecular_functionoxidoreductase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site551Proton donor By similarity PIRSR PIRSR000097-1

Sequences

Sequence LengthMass (Da)Tools
Q2XPP3 [UniParc].

Last modified December 20, 2005. Version 1.
Checksum: 23D42E6CB3C48ACF

FASTA32336,768
        10         20         30         40         50         60 
MDSKHQCVKL NDGHFMPVLG FGTYAPAEVP KSKALEATKL AIEAGFRHID SAHLYNNEEQ 

        70         80         90        100        110        120 
VGLAVRSKIA DGSVKREDIF YTSKLWCNSH RPELVRPALE RSLKKAQLDY VDLYLIHSPM 

       130        140        150        160        170        180 
SLKPGEELSP TDENGKVIFD IVDLCTTWEA MEKCKDAGLA KSIGVSNFNR RQLEMILNKP 

       190        200        210        220        230        240 
GLKYKPVCNQ VECHPYFNRS KLLDFCKSKD IVLVAYSALG SQRDKRWVDP NSPVLLEDPV 

       250        260        270        280        290        300 
LCALAKKHKR TPALIALRYQ LQRGVVVLAK SYNEQRIRQN VQVFEFQLTA EDMKAIDGLD 

       310        320 
RNLHYFNSDS FASHPNYPYS DEY 

« Hide

References

[1]"Overexpression of dihydrodiol dehydrogenase 2, AKR1C2, in bladder cancer patients from high-risk region of black foot disease in Taiwan."
Chow K.-C.
Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Bladder cancer EMBL ABB76132.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DQ269985 mRNA. Translation: ABB76132.1.
UniGeneHs.78183.

3D structure databases

ProteinModelPortalQ2XPP3.
SMRQ2XPP3. Positions 6-321.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ2XPP3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG000020.

Family and domain databases

Gene3D3.20.20.100. 1 hit.
InterProIPR001395. Aldo/ket_red.
IPR018170. Aldo/ket_reductase_CS.
IPR020471. Aldo/keto_reductase_subgr.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERPTHR11732. PTHR11732. 1 hit.
PfamPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
PIRSFPIRSF000097. AKR. 1 hit.
PRINTSPR00069. ALDKETRDTASE.
SUPFAMSSF51430. SSF51430. 1 hit.
PROSITEPS00798. ALDOKETO_REDUCTASE_1. 1 hit.
PS00062. ALDOKETO_REDUCTASE_2. 1 hit.
PS00063. ALDOKETO_REDUCTASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ2XPP3_HUMAN
AccessionPrimary (citable) accession number: Q2XPP3
Entry history
Integrated into UniProtKB/TrEMBL: December 20, 2005
Last sequence update: December 20, 2005
Last modified: June 11, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.