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Protein
Submitted name:

NK-1 receptor

Gene

nk-1

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
NK-1 receptorImported
Submitted name:
Tachykinin receptor 1Imported
Gene namesi
Name:nk-1Imported
Synonyms:TACR1Imported
OrganismiMacaca mulatta (Rhesus macaque)
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000006718 Componenti: Chromosome 13

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei32 – 58HelicalSequence analysisAdd BLAST27
Transmembranei70 – 90HelicalSequence analysisAdd BLAST21
Transmembranei110 – 128HelicalSequence analysisAdd BLAST19
Transmembranei149 – 168HelicalSequence analysisAdd BLAST20
Transmembranei195 – 225HelicalSequence analysisAdd BLAST31
Transmembranei246 – 273HelicalSequence analysisAdd BLAST28
Transmembranei285 – 308HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMMUG00000001846.

Interactioni

Protein-protein interaction databases

STRINGi9544.ENSMMUP00000002455.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini49 – 305G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST257

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG4219. Eukaryota.
ENOG410XSC5. LUCA.
GeneTreeiENSGT00900000140861.
HOGENOMiHOG000013018.
HOVERGENiHBG103412.
KOiK04222.
OMAiMIIVVCT.
OrthoDBiEOG091G0WYG.
TreeFamiTF315303.

Family and domain databases

InterProiView protein in InterPro
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001681. Neurokn_rcpt.
IPR000046. NK1_rcpt.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00237. GPCRRHODOPSN.
PR01024. NEUROKININ1R.
PR00244. NEUROKININR.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2WGM1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDNVLPVDSD LSANISTNTS EPNQFVQPAW QIVLWAAAYT VIVVTSVVGN
60 70 80 90 100
VVVMWIILAH KRMRTVTNYF LVNLAFAEAS MAAFNTVVNF TYAVHNEWYY
110 120 130 140 150
GLFYCKFHNF FPIAAVFASI YSMTAVAFDR YMAIIHPLQP RLSATATKVV
160 170 180 190 200
ICVIWVLALL LAFPQGYYST TETMPSRVVC MIEWPEHPNK IYEKVYHICV
210 220 230 240 250
TVLIYFLPLL VIGYAYTVVG ITLWASEIPG DSSDRYHEQV SAKRKVVKMM
260 270 280 290 300
IVVVCTFAIC WLPFHIFFLL PYINPDLYLK KFIQQVYLAI MWLAMSSTMY
310 320 330 340 350
NPIIYCCLND RFRLGFKHAF RCCPFISAGD YEGLEMKSTR YLQTQGSVYK
360 370 380 390 400
VSRLETTIST VVGAHEEEPE DGPKATPSSL DLTSNCSSRS DSKTMTESFS

FSSNVVS
Length:407
Mass (Da):46,211
Last modified:January 10, 2006 - v1
Checksum:i20518134D2D34545
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03011253 Genomic DNA. No translation available.
JSUE03011254 Genomic DNA. No translation available.
JSUE03011255 Genomic DNA. No translation available.
JSUE03011256 Genomic DNA. No translation available.
AB180074 mRNA. Translation: BAE53724.1.
RefSeqiNP_001032950.1. NM_001037861.1.
UniGeneiMmu.4899.

Genome annotation databases

EnsembliENSMMUT00000002600; ENSMMUP00000002455; ENSMMUG00000001846.
GeneIDi653008.
KEGGimcc:653008.

Similar proteinsi

Entry informationi

Entry nameiQ2WGM1_MACMU
AccessioniPrimary (citable) accession number: Q2WGM1
Entry historyiIntegrated into UniProtKB/TrEMBL: January 10, 2006
Last sequence update: January 10, 2006
Last modified: November 22, 2017
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported