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Protein
Submitted name:

NK-1 receptor

Gene

nk-1

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
NK-1 receptorImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:nk-1Imported
Synonyms:TACR1Imported
OrganismiMacaca mulatta (Rhesus macaque)
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000006718 Componenti: Chromosome 13

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei32 – 58HelicalSequence analysisAdd BLAST27
Transmembranei70 – 90HelicalSequence analysisAdd BLAST21
Transmembranei110 – 128HelicalSequence analysisAdd BLAST19
Transmembranei149 – 168HelicalSequence analysisAdd BLAST20
Transmembranei195 – 225HelicalSequence analysisAdd BLAST31
Transmembranei246 – 273HelicalSequence analysisAdd BLAST28
Transmembranei285 – 308HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMMUG00000001846.

Interactioni

Protein-protein interaction databases

STRINGi9544.ENSMMUP00000002455.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini49 – 305G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST257

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG4219. Eukaryota.
ENOG410XSC5. LUCA.
GeneTreeiENSGT00760000118781.
HOGENOMiHOG000013018.
HOVERGENiHBG103412.
KOiK04222.
OMAiMIIVVCT.
OrthoDBiEOG091G0WYG.
TreeFamiTF315303.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001681. Neurokn_rcpt.
IPR000046. NK1_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01024. NEUROKININ1R.
PR00244. NEUROKININR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2WGM1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDNVLPVDSD LSANISTNTS EPNQFVQPAW QIVLWAAAYT VIVVTSVVGN
60 70 80 90 100
VVVMWIILAH KRMRTVTNYF LVNLAFAEAS MAAFNTVVNF TYAVHNEWYY
110 120 130 140 150
GLFYCKFHNF FPIAAVFASI YSMTAVAFDR YMAIIHPLQP RLSATATKVV
160 170 180 190 200
ICVIWVLALL LAFPQGYYST TETMPSRVVC MIEWPEHPNK IYEKVYHICV
210 220 230 240 250
TVLIYFLPLL VIGYAYTVVG ITLWASEIPG DSSDRYHEQV SAKRKVVKMM
260 270 280 290 300
IVVVCTFAIC WLPFHIFFLL PYINPDLYLK KFIQQVYLAI MWLAMSSTMY
310 320 330 340 350
NPIIYCCLND RFRLGFKHAF RCCPFISAGD YEGLEMKSTR YLQTQGSVYK
360 370 380 390 400
VSRLETTIST VVGAHEEEPE DGPKATPSSL DLTSNCSSRS DSKTMTESFS

FSSNVVS
Length:407
Mass (Da):46,211
Last modified:January 10, 2006 - v1
Checksum:i20518134D2D34545
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03011253 Genomic DNA. No translation available.
JSUE03011254 Genomic DNA. No translation available.
JSUE03011255 Genomic DNA. No translation available.
JSUE03011256 Genomic DNA. No translation available.
AB180074 mRNA. Translation: BAE53724.1.
RefSeqiNP_001032950.1. NM_001037861.1.
UniGeneiMmu.4899.

Genome annotation databases

EnsembliENSMMUT00000002600; ENSMMUP00000002455; ENSMMUG00000001846.
GeneIDi653008.
KEGGimcc:653008.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03011253 Genomic DNA. No translation available.
JSUE03011254 Genomic DNA. No translation available.
JSUE03011255 Genomic DNA. No translation available.
JSUE03011256 Genomic DNA. No translation available.
AB180074 mRNA. Translation: BAE53724.1.
RefSeqiNP_001032950.1. NM_001037861.1.
UniGeneiMmu.4899.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9544.ENSMMUP00000002455.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMMUT00000002600; ENSMMUP00000002455; ENSMMUG00000001846.
GeneIDi653008.
KEGGimcc:653008.

Organism-specific databases

CTDi6869.

Phylogenomic databases

eggNOGiKOG4219. Eukaryota.
ENOG410XSC5. LUCA.
GeneTreeiENSGT00760000118781.
HOGENOMiHOG000013018.
HOVERGENiHBG103412.
KOiK04222.
OMAiMIIVVCT.
OrthoDBiEOG091G0WYG.
TreeFamiTF315303.

Gene expression databases

BgeeiENSMMUG00000001846.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001681. Neurokn_rcpt.
IPR000046. NK1_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01024. NEUROKININ1R.
PR00244. NEUROKININR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ2WGM1_MACMU
AccessioniPrimary (citable) accession number: Q2WGM1
Entry historyi
Integrated into UniProtKB/TrEMBL: January 10, 2006
Last sequence update: January 10, 2006
Last modified: November 30, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.