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Protein
Submitted name:

NK-3 receptor

Gene

nk-3

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
NK-3 receptorImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:nk-3Imported
Synonyms:TACR3Imported
ORF Names:EGK_15980Imported
OrganismiMacaca mulatta (Rhesus macaque)
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000006718 Componenti: Chromosome 5

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei85 – 11127HelicalSequence analysisAdd
BLAST
Transmembranei123 – 14826HelicalSequence analysisAdd
BLAST
Transmembranei160 – 18122HelicalSequence analysisAdd
BLAST
Transmembranei202 – 22120HelicalSequence analysisAdd
BLAST
Transmembranei247 – 27630HelicalSequence analysisAdd
BLAST
Transmembranei297 – 32529HelicalSequence analysisAdd
BLAST
Transmembranei337 – 35923HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Chemistry

ChEMBLiCHEMBL3421526.

Expressioni

Gene expression databases

BgeeiENSMMUG00000020290.

Interactioni

Protein-protein interaction databases

STRINGi9544.ENSMMUP00000026703.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini102 – 356255G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG4219. Eukaryota.
ENOG410XSC5. LUCA.
GeneTreeiENSGT00760000118781.
HOGENOMiHOG000013018.
HOVERGENiHBG103412.
KOiK04224.
OMAiVMTFAIC.
OrthoDBiEOG091G0WYG.
TreeFamiTF315303.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001681. Neurokn_rcpt.
IPR001013. NK3_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01026. NEUROKININ3R.
PR00244. NEUROKININR.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2WGM0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATLPAAETW IDGGGGVGAD AVNLTASLAA GAATGTVETG WLQLLDQAGN
60 70 80 90 100
LSSSPSALGL PVASPAPSQP RANLTNQFVQ PSWRIALWSL AYGVVVAVAV
110 120 130 140 150
FGNLIVIWII LAHKRMRTVT NYFLVNLAFS DASMAAFNTL VNFIYALHSE
160 170 180 190 200
WYFGANYCRF QNFFPITAVF ASIYSMTAIA VDRYMAIIDP LKPRLSATAT
210 220 230 240 250
KIVIGSIWIL AFLLAFPQCL YSKTKVMPGR TLCFVQWPEG PKQHFTYHII
260 270 280 290 300
VIILVYCFPL LIMGITYTIV GITLWGGEIP GDTCDKYHEQ LKAKRKVVKM
310 320 330 340 350
MIIVVMTFAI CWLPYHIYFI LTAIYQQLNR WKYIQQVYLA SFWLAMSSTM
360 370 380 390 400
YNPIIYCCLN KRFRAGFKRA FRWCPFIKVS SYDELELKTT RFHPTRQSSM
410 420 430 440 450
YTVTRMESMT VMFDPSDADT ARSSRKKRAT PRDPSFNGCS RRNSKSASTT
460
SSFISSPYTS VDE
Length:463
Mass (Da):51,978
Last modified:January 10, 2006 - v1
Checksum:i869E48B48B011B12
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB180075 mRNA. Translation: BAE53725.1.
CM001257 Genomic DNA. Translation: EHH26092.1.
RefSeqiNP_001032951.1. NM_001037862.1.
UniGeneiMmu.4891.

Genome annotation databases

EnsembliENSMMUT00000028540; ENSMMUP00000026703; ENSMMUG00000020290.
GeneIDi653013.
KEGGimcc:653013.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB180075 mRNA. Translation: BAE53725.1.
CM001257 Genomic DNA. Translation: EHH26092.1.
RefSeqiNP_001032951.1. NM_001037862.1.
UniGeneiMmu.4891.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9544.ENSMMUP00000026703.

Chemistry

ChEMBLiCHEMBL3421526.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMMUT00000028540; ENSMMUP00000026703; ENSMMUG00000020290.
GeneIDi653013.
KEGGimcc:653013.

Organism-specific databases

CTDi6870.

Phylogenomic databases

eggNOGiKOG4219. Eukaryota.
ENOG410XSC5. LUCA.
GeneTreeiENSGT00760000118781.
HOGENOMiHOG000013018.
HOVERGENiHBG103412.
KOiK04224.
OMAiVMTFAIC.
OrthoDBiEOG091G0WYG.
TreeFamiTF315303.

Gene expression databases

BgeeiENSMMUG00000020290.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001681. Neurokn_rcpt.
IPR001013. NK3_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01026. NEUROKININ3R.
PR00244. NEUROKININR.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ2WGM0_MACMU
AccessioniPrimary (citable) accession number: Q2WGM0
Entry historyi
Integrated into UniProtKB/TrEMBL: January 10, 2006
Last sequence update: January 10, 2006
Last modified: September 7, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.