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Protein
Submitted name:

NK-3 receptor

Gene

nk-3

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
NK-3 receptorImported
Gene namesi
Name:nk-3Imported
ORF Names:EGK_15980Imported
OrganismiMacaca mulatta (Rhesus macaque)
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei85 – 111HelicalSequence analysisAdd BLAST27
Transmembranei123 – 148HelicalSequence analysisAdd BLAST26
Transmembranei160 – 181HelicalSequence analysisAdd BLAST22
Transmembranei202 – 221HelicalSequence analysisAdd BLAST20
Transmembranei247 – 276HelicalSequence analysisAdd BLAST30
Transmembranei297 – 325HelicalSequence analysisAdd BLAST29
Transmembranei337 – 359HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL3421526.

Expressioni

Gene expression databases

BgeeiENSMMUG00000020290.

Interactioni

Protein-protein interaction databases

STRINGi9544.ENSMMUP00000026703.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini102 – 356G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST255

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG4219. Eukaryota.
ENOG410XSC5. LUCA.
HOGENOMiHOG000013018.
HOVERGENiHBG103412.
KOiK04224.
OMAiVMTFAIC.
OrthoDBiEOG091G0WYG.
TreeFamiTF315303.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001681. Neurokn_rcpt.
IPR001013. NK3_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01026. NEUROKININ3R.
PR00244. NEUROKININR.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2WGM0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATLPAAETW IDGGGGVGAD AVNLTASLAA GAATGTVETG WLQLLDQAGN
60 70 80 90 100
LSSSPSALGL PVASPAPSQP RANLTNQFVQ PSWRIALWSL AYGVVVAVAV
110 120 130 140 150
FGNLIVIWII LAHKRMRTVT NYFLVNLAFS DASMAAFNTL VNFIYALHSE
160 170 180 190 200
WYFGANYCRF QNFFPITAVF ASIYSMTAIA VDRYMAIIDP LKPRLSATAT
210 220 230 240 250
KIVIGSIWIL AFLLAFPQCL YSKTKVMPGR TLCFVQWPEG PKQHFTYHII
260 270 280 290 300
VIILVYCFPL LIMGITYTIV GITLWGGEIP GDTCDKYHEQ LKAKRKVVKM
310 320 330 340 350
MIIVVMTFAI CWLPYHIYFI LTAIYQQLNR WKYIQQVYLA SFWLAMSSTM
360 370 380 390 400
YNPIIYCCLN KRFRAGFKRA FRWCPFIKVS SYDELELKTT RFHPTRQSSM
410 420 430 440 450
YTVTRMESMT VMFDPSDADT ARSSRKKRAT PRDPSFNGCS RRNSKSASTT
460
SSFISSPYTS VDE
Length:463
Mass (Da):51,978
Last modified:January 10, 2006 - v1
Checksum:i869E48B48B011B12
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB180075 mRNA. Translation: BAE53725.1.
CM001257 Genomic DNA. Translation: EHH26092.1.
RefSeqiNP_001032951.1. NM_001037862.1.
UniGeneiMmu.4891.

Genome annotation databases

GeneIDi653013.
KEGGimcc:653013.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB180075 mRNA. Translation: BAE53725.1.
CM001257 Genomic DNA. Translation: EHH26092.1.
RefSeqiNP_001032951.1. NM_001037862.1.
UniGeneiMmu.4891.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9544.ENSMMUP00000026703.

Chemistry databases

ChEMBLiCHEMBL3421526.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi653013.
KEGGimcc:653013.

Organism-specific databases

CTDi6870.

Phylogenomic databases

eggNOGiKOG4219. Eukaryota.
ENOG410XSC5. LUCA.
HOGENOMiHOG000013018.
HOVERGENiHBG103412.
KOiK04224.
OMAiVMTFAIC.
OrthoDBiEOG091G0WYG.
TreeFamiTF315303.

Gene expression databases

BgeeiENSMMUG00000020290.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001681. Neurokn_rcpt.
IPR001013. NK3_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01026. NEUROKININ3R.
PR00244. NEUROKININR.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ2WGM0_MACMU
AccessioniPrimary (citable) accession number: Q2WGM0
Entry historyi
Integrated into UniProtKB/TrEMBL: January 10, 2006
Last sequence update: January 10, 2006
Last modified: November 30, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.