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Q2W9Z8

- UPPP1_MAGSA

UniProt

Q2W9Z8 - UPPP1_MAGSA

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Protein

Undecaprenyl-diphosphatase 1

Gene

uppP1

Organism
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.UniRule annotation

Catalytic activityi

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate.UniRule annotation

GO - Molecular functioni

  1. undecaprenyl-diphosphatase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. cell wall organization Source: UniProtKB-KW
  2. dephosphorylation Source: InterPro
  3. peptidoglycan biosynthetic process Source: UniProtKB-KW
  4. regulation of cell shape Source: UniProtKB-KW
  5. response to antibiotic Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Antibiotic resistance, Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciMMAG342108:GJNU-528-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Undecaprenyl-diphosphatase 1UniRule annotation (EC:3.6.1.27UniRule annotation)
Alternative name(s):
Bacitracin resistance protein 1UniRule annotation
Undecaprenyl pyrophosphate phosphatase 1UniRule annotation
Gene namesi
Name:uppP1UniRule annotation
Ordered Locus Names:amb0523
OrganismiMagnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Taxonomic identifieri342108 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeMagnetospirillum
ProteomesiUP000007058: Chromosome

Subcellular locationi

Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 267267Undecaprenyl-diphosphatase 1PRO_0000250242Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi342108.amb0523.

Structurei

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei6 – 2621HelicalUniRule annotationAdd
BLAST
Transmembranei41 – 6020HelicalUniRule annotationAdd
BLAST
Transmembranei83 – 10321HelicalUniRule annotationAdd
BLAST
Transmembranei109 – 12921HelicalUniRule annotationAdd
BLAST
Transmembranei142 – 16221HelicalUniRule annotationAdd
BLAST
Transmembranei185 – 20521HelicalUniRule annotationAdd
BLAST
Transmembranei217 – 23721HelicalUniRule annotationAdd
BLAST
Transmembranei244 – 26421HelicalUniRule annotationAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the UppP family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1968.
HOGENOMiHOG000218357.
KOiK06153.
OMAiYISVRFL.
OrthoDBiEOG6QP13M.

Family and domain databases

HAMAPiMF_01006. Undec_diphosphatase.
InterProiIPR003824. UppP.
[Graphical view]
PfamiPF02673. BacA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2W9Z8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTFLEVLVVA LIQGLGEVLP FGAAGLLAAL PHLAAKPEGR AALSVAAHAG
60 70 80 90 100
ILLALMIYFW RDVLAMAVGL WRLAKGKPDY GSHLLLHVLA GTIPAAIVGW
110 120 130 140 150
LVLDRASTLV GQSGAAIILI LGGVLLWGCD KLGVTVRRVE HMSWVGAAGL
160 170 180 190 200
GALQILSLVP GVSRTGITVT VARLLGWERQ AAVRFSMLLA MPLILGHGVK
210 220 230 240 250
TFWGLAHHTE LVFSSDLLMA MATAGLAALI GLAGMMAWVA RNTFVPFAIL
260
RIGFGIAVLG LVYFGQA
Length:267
Mass (Da):27,964
Last modified:January 10, 2006 - v1
Checksum:i903DEDA6FB6A41BD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP007255 Genomic DNA. Translation: BAE49327.1.
RefSeqiYP_419886.1. NC_007626.1.

Genome annotation databases

EnsemblBacteriaiBAE49327; BAE49327; amb0523.
GeneIDi3805817.
KEGGimag:amb0523.
PATRICi22435336. VBIMagMag129836_0535.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP007255 Genomic DNA. Translation: BAE49327.1 .
RefSeqi YP_419886.1. NC_007626.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 342108.amb0523.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAE49327 ; BAE49327 ; amb0523 .
GeneIDi 3805817.
KEGGi mag:amb0523.
PATRICi 22435336. VBIMagMag129836_0535.

Phylogenomic databases

eggNOGi COG1968.
HOGENOMi HOG000218357.
KOi K06153.
OMAi YISVRFL.
OrthoDBi EOG6QP13M.

Enzyme and pathway databases

BioCyci MMAG342108:GJNU-528-MONOMER.

Family and domain databases

HAMAPi MF_01006. Undec_diphosphatase.
InterProi IPR003824. UppP.
[Graphical view ]
Pfami PF02673. BacA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of the facultative anaerobic magnetotactic bacterium Magnetospirillum sp. strain AMB-1."
    Matsunaga T., Okamura Y., Fukuda Y., Wahyudi A.T., Murase Y., Takeyama H.
    DNA Res. 12:157-166(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AMB-1 / ATCC 700264.

Entry informationi

Entry nameiUPPP1_MAGSA
AccessioniPrimary (citable) accession number: Q2W9Z8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 19, 2006
Last sequence update: January 10, 2006
Last modified: October 29, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3