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Q2W9Z8 (UPPP1_MAGSA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase 1

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein 1
Undecaprenyl pyrophosphate phosphatase 1
Gene names
Name:uppP1
Ordered Locus Names:amb0523
OrganismMagnetospirillum magneticum (strain AMB-1 / ATCC 700264) [Complete proteome] [HAMAP]
Taxonomic identifier342108 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeMagnetospirillum

Protein attributes

Sequence length267 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 267267Undecaprenyl-diphosphatase 1 HAMAP-Rule MF_01006
PRO_0000250242

Regions

Transmembrane6 – 2621Helical; Potential
Transmembrane41 – 6020Helical; Potential
Transmembrane83 – 10321Helical; Potential
Transmembrane109 – 12921Helical; Potential
Transmembrane142 – 16221Helical; Potential
Transmembrane185 – 20521Helical; Potential
Transmembrane217 – 23721Helical; Potential
Transmembrane244 – 26421Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q2W9Z8 [UniParc].

Last modified January 10, 2006. Version 1.
Checksum: 903DEDA6FB6A41BD

FASTA26727,964
        10         20         30         40         50         60 
MTFLEVLVVA LIQGLGEVLP FGAAGLLAAL PHLAAKPEGR AALSVAAHAG ILLALMIYFW 

        70         80         90        100        110        120 
RDVLAMAVGL WRLAKGKPDY GSHLLLHVLA GTIPAAIVGW LVLDRASTLV GQSGAAIILI 

       130        140        150        160        170        180 
LGGVLLWGCD KLGVTVRRVE HMSWVGAAGL GALQILSLVP GVSRTGITVT VARLLGWERQ 

       190        200        210        220        230        240 
AAVRFSMLLA MPLILGHGVK TFWGLAHHTE LVFSSDLLMA MATAGLAALI GLAGMMAWVA 

       250        260 
RNTFVPFAIL RIGFGIAVLG LVYFGQA 

« Hide

References

[1]"Complete genome sequence of the facultative anaerobic magnetotactic bacterium Magnetospirillum sp. strain AMB-1."
Matsunaga T., Okamura Y., Fukuda Y., Wahyudi A.T., Murase Y., Takeyama H.
DNA Res. 12:157-166(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AMB-1 / ATCC 700264.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP007255 Genomic DNA. Translation: BAE49327.1.
RefSeqYP_419886.1. NC_007626.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING342108.amb0523.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAE49327; BAE49327; amb0523.
GeneID3805817.
KEGGmag:amb0523.
PATRIC22435336. VBIMagMag129836_0535.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMAKARETWM.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycMMAG342108:GJNU-528-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUPPP1_MAGSA
AccessionPrimary (citable) accession number: Q2W9Z8
Entry history
Integrated into UniProtKB/Swiss-Prot: September 19, 2006
Last sequence update: January 10, 2006
Last modified: February 19, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families