Q2W9C3 (KGUA_MAGSA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Guanylate kinase
EC=2.7.4.8

Alternative name(s):
GMP kinase

Gene names

Name:	gmk
Ordered Locus Names:	amb0748

Organism

Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) [Complete proteome] [HAMAP]

Taxonomic identifier

342108 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Rhodospirillaceae › Magnetospirillum › Magnetospirillum magneticum

Protein attributes

Sequence length	214 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Essential for recycling GMP and indirectly, cGMP By similarity. HAMAP-Rule MF_00328
Catalytic activity	ATP + GMP = ADP + GDP. HAMAP-Rule MF_00328
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00328.
Sequence similarities	Belongs to the guanylate kinase family. Contains 1 guanylate kinase-like domain.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	purine nucleotide metabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW guanylate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 214	214	Guanylate kinase HAMAP-Rule MF_00328		PRO_0000266344
Regions
	Domain	12 – 191	180	Guanylate kinase-like
	Nucleotide binding	19 – 26	8	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2W9C3 [UniParc]. Last modified January 10, 2006. Version 1. Checksum: 497CED3A7CF5B0DF	FASTA	214	24,086
	10 20 30 40 50 60 MTDTLPTVSR RGLMLVMSSP SGAGKTTISR ALLERDPAIG MSVSATTRAP RPGEVDGKDY 70 80 90 100 110 120 HFVTVEKFHE MVEKREFLEH ARVFDNFYGT PRGPVDEILR SGRDVLFDID WQGTQQMAQN 130 140 150 160 170 180 ARADLVSVFV LPPSVEELER RLRGRAQDSD EVVRKRMAKA GDEMSHWPEY DYIVVNIDLD 190 200 210 KSIAAVQAIL AAERLKRERQ VGLPDFVTQL RGGE

References

[1]

"Complete genome sequence of the facultative anaerobic magnetotactic bacterium Magnetospirillum sp. strain AMB-1." Matsunaga T., Okamura Y., Fukuda Y., Wahyudi A.T., Murase Y., Takeyama H. DNA Res. 12:157-166(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AMB-1 / ATCC 700264.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP007255 Genomic DNA. Translation: BAE49552.1.
RefSeq	YP_420111.1. NC_007626.1.
3D structure databases
ProteinModelPortal	Q2W9C3.
ModBase	Search...
Protein-protein interaction databases
STRING	342108.amb0748.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAE49552; BAE49552; amb0748.
GeneID	3803419.
KEGG	mag:amb0748.
PATRIC	22435792. VBIMagMag129836_0760.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0194.
HOGENOM	HOG000037638.
KO	K00942.
OMA	FVIINEL.
ProtClustDB	PRK00300.
Enzyme and pathway databases
BioCyc	MMAG342108:GJNU-756-MONOMER.
Family and domain databases
HAMAP	MF_00328. Guanylate_kinase.
InterPro	IPR008144. Guanylate_kin. IPR008145. Guanylate_kin/L-typ_Ca_channel. IPR020590. Guanylate_kinase_CS. IPR017665. Guanylate_kinase_sub. IPR027417. P-loop_NTPase. [Graphical view]
Pfam	PF00625. Guanylate_kin. 1 hit. [Graphical view]
SMART	SM00072. GuKc. 1 hit. [Graphical view]
SUPFAM	SSF52540. SSF52540. 1 hit.
TIGRFAMs	TIGR03263. guanyl_kin. 1 hit.
PROSITE	PS00856. GUANYLATE_KINASE_1. 1 hit. PS50052. GUANYLATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

KGUA_MAGSA

Accession

Primary (citable) accession number: Q2W9C3

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 12, 2006
Last sequence update:	January 10, 2006
Last modified:	May 29, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program