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Q2W9A3

- GCSPA_MAGSA

UniProt

Q2W9A3 - GCSPA_MAGSA

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Protein

Probable glycine dehydrogenase (decarboxylating) subunit 1

Gene
gcvPA, amb0768
Organism
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO2 is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein By similarity.UniRule annotation

Catalytic activityi

Glycine + [glycine-cleavage complex H protein]-N(6)-lipoyl-L-lysine = [glycine-cleavage complex H protein]-S-aminomethyl-N(6)-dihydrolipoyl-L-lysine + CO2.UniRule annotation

GO - Molecular functioni

  1. glycine dehydrogenase (decarboxylating) activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glycine catabolic process Source: InterPro
  2. nucleoside metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciMMAG342108:GJNU-776-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glycine dehydrogenase (decarboxylating) subunit 1 (EC:1.4.4.2)
Alternative name(s):
Glycine cleavage system P-protein subunit 1
Glycine decarboxylase subunit 1
Glycine dehydrogenase (aminomethyl-transferring) subunit 1
Gene namesi
Name:gcvPA
Ordered Locus Names:amb0768
OrganismiMagnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Taxonomic identifieri342108 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeMagnetospirillum
ProteomesiUP000007058: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 449449Probable glycine dehydrogenase (decarboxylating) subunit 1UniRule annotationPRO_1000045665Add
BLAST

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits By similarity.

Protein-protein interaction databases

STRINGi342108.amb0768.

Structurei

3D structure databases

ProteinModelPortaliQ2W9A3.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0403.
HOGENOMiHOG000132025.
KOiK00282.
OMAiRLVGQTE.
OrthoDBiEOG6XWV3B.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
HAMAPiMF_00712. GcvPA.
InterProiIPR023010. GcvPA.
IPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11773. PTHR11773. 1 hit.
PfamiPF02347. GDC-P. 1 hit.
[Graphical view]
PIRSFiPIRSF006815. GcvPA. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2W9A3-1 [UniParc]FASTAAdd to Basket

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MRYLPLTEAD RRAMLDVIGA KSVDDLFRDV PPSARLAGPL PLPSHQGEME    50
VERAFTRMAG KNLSAGCAPF FIGAGVYRHH VPAAVDQLLL RGEFLTAYTP 100
YQPEVSQGTL QMLFEFQSQV ATITGMDVAN ASMYDGATAC AEAAIMACRI 150
TKRNRVIVSG GVHPHYAETL ETSLRFTEME ADVLPPDPLG MEDMIGRVDS 200
KTACVVVQNP GFFGTVRDLR PLAALCHEAG ALLVVMVAEP TSLGLIESPG 250
AMGADIVVCE GQSLGMGLNF GGPGLGLFAT RDKYVRQMPG RLVGQTADVD 300
GRRGWVLTLS TREQHIRREK ATSNICTNSG LCALAFSIHL TMLGGTGFGR 350
LAELNHLAAT RLEQKLRAVK GLRVLPQSYY NEFAVHLGDD ADAAAVVDAL 400
ADKGILAGVP ASRFYPTWPE LKPVLILAAT ETNTEDDMDR LVAGLQEVL 449
Length:449
Mass (Da):48,282
Last modified:January 10, 2006 - v1
Checksum:i427AB2C23B7A27A7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP007255 Genomic DNA. Translation: BAE49572.1.
RefSeqiWP_011383211.1. NC_007626.1.
YP_420131.1. NC_007626.1.

Genome annotation databases

EnsemblBacteriaiBAE49572; BAE49572; amb0768.
GeneIDi3806335.
KEGGimag:amb0768.
PATRICi22435830. VBIMagMag129836_0779.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP007255 Genomic DNA. Translation: BAE49572.1 .
RefSeqi WP_011383211.1. NC_007626.1.
YP_420131.1. NC_007626.1.

3D structure databases

ProteinModelPortali Q2W9A3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 342108.amb0768.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAE49572 ; BAE49572 ; amb0768 .
GeneIDi 3806335.
KEGGi mag:amb0768.
PATRICi 22435830. VBIMagMag129836_0779.

Phylogenomic databases

eggNOGi COG0403.
HOGENOMi HOG000132025.
KOi K00282.
OMAi RLVGQTE.
OrthoDBi EOG6XWV3B.

Enzyme and pathway databases

BioCyci MMAG342108:GJNU-776-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
HAMAPi MF_00712. GcvPA.
InterProi IPR023010. GcvPA.
IPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view ]
PANTHERi PTHR11773. PTHR11773. 1 hit.
Pfami PF02347. GDC-P. 1 hit.
[Graphical view ]
PIRSFi PIRSF006815. GcvPA. 1 hit.
SUPFAMi SSF53383. SSF53383. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of the facultative anaerobic magnetotactic bacterium Magnetospirillum sp. strain AMB-1."
    Matsunaga T., Okamura Y., Fukuda Y., Wahyudi A.T., Murase Y., Takeyama H.
    DNA Res. 12:157-166(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AMB-1 / ATCC 700264.

Entry informationi

Entry nameiGCSPA_MAGSA
AccessioniPrimary (citable) accession number: Q2W9A3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 10, 2006
Last modified: September 3, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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