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Q2W724 (UPPP2_MAGSA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase 2
EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein 2
Undecaprenyl pyrophosphate phosphatase 2
Gene names
Name:uppP2
Ordered Locus Names:amb1547
OrganismMagnetospirillum magneticum (strain AMB-1 / ATCC 700264) [Complete proteome] [HAMAP]
Taxonomic identifier342108 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Rhodospirillaceae › Magnetospirillum

Protein attributes

Sequence length261 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP MF_01006

Catalytic activity

Undecaprenyl diphosphate + H2O = undecaprenyl phosphate + phosphate. HAMAP MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available. HAMAP MF_01006

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 261261Undecaprenyl-diphosphatase 2 HAMAP MF_01006
PRO_0000250243

Regions

Transmembrane1 – 2121Helical; Potential
Transmembrane38 – 5821Helical; Potential
Transmembrane75 – 9521Helical; Potential
Transmembrane103 – 12321Helical; Potential
Transmembrane138 – 15821Helical; Potential
Transmembrane178 – 19821Helical; Potential
Transmembrane212 – 23221Helical; Potential
Transmembrane240 – 26021Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q2W724 [UniParc].

Last modified January 10, 2006. Version 1.
Checksum: 0E7A3C1C5BA8ED35

FASTA26127,807
        10         20         30         40         50         60 
MLEALLLGVV EGLTEFLPIS STAHLMLIGD MLGFEGPPGK TYEIVVQLGA ILAVCVVFRQ 

        70         80         90        100        110        120 
RLWGVATTIT QPRSFAFARN VMVAFLPAAV IGATLYKYIK QMLESPLVAA IALVVGGVAI 

       130        140        150        160        170        180 
LVIERLVKRA RIHDIEDMSP ALALGVGFCQ VLAMVPGVSR AGATIMGSML LGLDRRAAAE 

       190        200        210        220        230        240 
FSFFLAIPTM CGASAYSLYK NWATLSFDGA GLIALGFVAA FLSALVVVKG FIGFVGRHGF 

       250        260 
APFAWYRIAF GSLMAVLILM R

« Hide

References

[1]"Complete genome sequence of the facultative anaerobic magnetotactic bacterium Magnetospirillum sp. strain AMB-1."
Matsunaga T., Okamura Y., Fukuda Y., Wahyudi A.T., Murase Y., Takeyama H.
DNA Res. 12:157-166(2005) [PubMed: 16303747] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AMB-1 / ATCC 700264.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP007255 Genomic DNA. Translation: BAE50351.1.
RefSeqYP_420910.1. NC_007626.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ2W724.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3806467.
GenomeReviewsGene locus amb1547 in contig AP007255_GR.
KEGGmag:amb1547.
NMPDRfig|342108.5.peg.1380.
PATRIC22437359. VBIMagMag129836_1534.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHBG391969.
OMAPERENVT.
PhylomeDBQ2W724.
ProtClustDBPRK00281.

Enzyme and pathway databases

BioCycMMAG342108:AMB1547-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
[Tree]
InterProIPR003824. Bacitracin-R_BacA.
[Graphical view]
KOK06153.
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. Undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP2_MAGSA
AccessionPrimary (citable) accession number: Q2W724
Entry history
Integrated into UniProtKB/Swiss-Prot: September 19, 2006
Last sequence update: January 10, 2006
Last modified: January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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