ID   Q2W536_MAGSA            Unreviewed;       684 AA.
AC   Q2W536;
DT   10-JAN-2006, integrated into UniProtKB/TrEMBL.
DT   10-JAN-2006, sequence version 1.
DT   27-MAR-2024, entry version 88.
DE   SubName: Full=Adenylate cyclase {ECO:0000313|EMBL:BAE51039.1};
GN   OrderedLocusNames=amb2235 {ECO:0000313|EMBL:BAE51039.1};
OS   Magnetospirillum magneticum (strain AMB-1 / ATCC 700264).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Magnetospirillaceae; Paramagnetospirillum.
OX   NCBI_TaxID=342108 {ECO:0000313|EMBL:BAE51039.1, ECO:0000313|Proteomes:UP000007058};
RN   [1] {ECO:0000313|EMBL:BAE51039.1, ECO:0000313|Proteomes:UP000007058}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AMB-1 / ATCC 700264 {ECO:0000313|Proteomes:UP000007058};
RX   PubMed=16303747; DOI=10.1093/dnares/dsi002;
RA   Matsunaga T., Okamura Y., Fukuda Y., Wahyudi A.T., Murase Y., Takeyama H.;
RT   "Complete genome sequence of the facultative anaerobic magnetotactic
RT   bacterium Magnetospirillum sp. strain AMB-1.";
RL   DNA Res. 12:157-166(2005).
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DR   EMBL; AP007255; BAE51039.1; -; Genomic_DNA.
DR   RefSeq; WP_011384633.1; NC_007626.1.
DR   AlphaFoldDB; Q2W536; -.
DR   STRING; 342108.amb2235; -.
DR   KEGG; mag:amb2235; -.
DR   HOGENOM; CLU_000445_85_1_5; -.
DR   OrthoDB; 9762462at2; -.
DR   Proteomes; UP000007058; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR007890; CHASE2.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR   Pfam; PF05226; CHASE2; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM01080; CHASE2; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007058};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        315..332
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        339..357
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        363..380
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          428..560
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   684 AA;  75784 MW;  C6550C0D048875C0 CRC64;
     MAKRYDILFT LILFLVAIPA QHFEWFALLE DQTLSFRHQL RLAYGDAKKL AVSPEVVVVN
     TDEAFFKAYK SFPLRRTDIG TMVTNLKALG AKVIAVDMLM DFPSSYNEDP ALAKALSDAG
     NTVLVAQGEF RDGKFAKINY PTTLLDQASA SAYTNIQSNS KLITSLSRLR VFPEMTAEKG
     GWPFAVKAAA MYLGVEPRLD GTTLVLGELR VPLNHEHKLY IDFPPLPTGT RFLSQSAGLS
     ALEFLDISGL DERELAELEY WVKDKIVVLG DTSEVSHDWF DTPVGMVYGV EIIADSISSI
     LKGAPLRGAG PVMDSVAPVV LLLAMLLLSL YLTRPLLRGM FVVALGVGFI VSASALYVHL
     GVVISMSYGV LALVLSYLLV EFRQYLIERN QKQQIAKTFG QYIPPELVAE MNKTGQQVTV
     GGESREMTVL FSDVRGFTTI SEGLAPQQLT VLMNAFLSPM THVIHDFRGT IDKYMGDAIM
     AFWGAPLHDP DHARHAVQAA LGMVKKMEEL KDDFVARGWK PIKVGIGLNT GIMNVGNMGS
     DFRMAYTVLG DAVNLGSRVE SLTKQYGVNM MVTEYTQAAV PGLISREIDL VRVKGKDTPV
     RLYEPLGFEG EVDAETVARL SQHLAALAMF REQKWDAARM AFQELHNSDP ERVIYKIYLG
     RIEHFMEEPP GTDWDGVYTH KEKS
//