ID   Q2W153_MAGSA            Unreviewed;       742 AA.
AC   Q2W153;
DT   10-JAN-2006, integrated into UniProtKB/TrEMBL.
DT   10-JAN-2006, sequence version 1.
DT   27-MAR-2024, entry version 104.
DE   SubName: Full=Adenylate cyclase 1 {ECO:0000313|EMBL:BAE52422.1};
GN   OrderedLocusNames=amb3618 {ECO:0000313|EMBL:BAE52422.1};
OS   Magnetospirillum magneticum (strain AMB-1 / ATCC 700264).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Magnetospirillaceae; Paramagnetospirillum.
OX   NCBI_TaxID=342108 {ECO:0000313|EMBL:BAE52422.1, ECO:0000313|Proteomes:UP000007058};
RN   [1] {ECO:0000313|EMBL:BAE52422.1, ECO:0000313|Proteomes:UP000007058}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AMB-1 / ATCC 700264 {ECO:0000313|Proteomes:UP000007058};
RX   PubMed=16303747; DOI=10.1093/dnares/dsi002;
RA   Matsunaga T., Okamura Y., Fukuda Y., Wahyudi A.T., Murase Y., Takeyama H.;
RT   "Complete genome sequence of the facultative anaerobic magnetotactic
RT   bacterium Magnetospirillum sp. strain AMB-1.";
RL   DNA Res. 12:157-166(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the adenylyl cyclase class-3 family.
CC       {ECO:0000256|ARBA:ARBA00005381}.
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DR   EMBL; AP007255; BAE52422.1; -; Genomic_DNA.
DR   RefSeq; WP_011385976.1; NC_007626.1.
DR   AlphaFoldDB; Q2W153; -.
DR   STRING; 342108.amb3618; -.
DR   KEGG; mag:amb3618; -.
DR   HOGENOM; CLU_021956_0_0_5; -.
DR   OrthoDB; 9762462at2; -.
DR   Proteomes; UP000007058; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   CDD; cd12913; PDC1_MCP_like; 1.
DR   CDD; cd12912; PDC2_MCP_like; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   PANTHER; PTHR43081:SF16; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC; 1.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007058};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          401..454
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          481..613
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   742 AA;  80462 MW;  D2970283E735E2AB CRC64;
     MNSMPPVPET PSGAPPNGAS AGDARDRRRK KRGKGLTLRV NILGAFAALL TVTVITLVAF
     AYHKNSASVL ELMGRFVERV SASGISSSMA LLDPVETSVQ ATARLAAIDE AKARDGSLFP
     YMTSILATQP QLQSIYLAFD ADGRFLQAFP IPPGTRKFGA HDTQPPENAR FALRVVDRKG
     GKYTDVWTYV TAAGAVVGEE TSNELNYDPR PRPWYKDAIA TKGLIWSDLL VYTSNRQPGI
     TAAYPIFAAD GRVIGAAAAN VATKQMSDFL ASLDLGGSGM AFIVDEKEQL IAHPDAARTV
     RQDGLKYSLV KADQLGEQVI ADAFAAYRSA KTRTVSFDSG GKRHLGSFNP FPTDLGKNWL
     MVIIVLEDDF VGTLKENSRD LVAVGFAVMV IGLLLVALLS SWITRPLTLL IHEIQKIQKF
     DLAGPIALHA IVAEVNELIH SMNMMKRALR TFGMFVPRDL VRELVASGRA IELGGQDRTL
     TVMFTDVADF TGLSERMAAG DLLVHISRHL AAISECVAEE DGTVDKYVGD AVMAFWGAPV
     WRDDHALRGC IAALKARETQ ARMNAEWAAQ GLPTMFVRIG LHTAPVIVGN IGSAWRMSYT
     AMGDGVNVAS RLEGVNKAYG TQICVSQAVL DAAGPGVLAR PLDLVAVKGR KAGALVYELM
     ALRDGVPELA PTAEQLEICR MTEEAFTAYQ DRRWSDSIAA YERLAALAPS DKLPAIFIER
     CRHFLAEPPP PEWIGVYEMK TK
//