Unreviewed, UniProtKB/TrEMBL Q2VI00 (Q2VI00_HUMAN)

Names and origin

Protein names	Submitted name:     Potassium chloride cotransporter KCC3a-S3 EMBL ABA02873.1
Organism	Homo sapiens (Human) EMBL ABA02873.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1141 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Gene Ontology (GO)
Biological process	chloride transport Inferred from electronic annotation. Source: InterPro sodium ion transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: InterPro
Molecular function	cation:chloride symporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2VI00-1 [UniParc]. Last modified January 10, 2006. Version 1. Checksum: 1B71C660733649AF	FASTA	1,141	126,594
	10 20 30 40 50 60 MASVRFMVTP TKIDDIPGLS DTSPDLSSRS SSRVRFSSRE SVPETSRSEP MSEMSGATTS 70 80 90 100 110 120 LATVALDPPS DRTSHPQDVI EDLSQNSITG EHSQLLDDGH KKARNAYLNN SNYEEGDEYF 130 140 150 160 170 180 DKNLALFEEE MDTRPKVSSL LNRMANYTNL TQGAKEHEEA ENITEGKKKP TKTPQMGTFM 190 200 210 220 230 240 GVYLPCLQNI FGVILFLRLT WVVGTAGVLQ AFAIVLICCC CTMLTAISMS AIATNGVVPA 250 260 270 280 290 300 GGSYFMISRA LGPEFGGAVG LCFYLGTTFA AAMYILGAIE IFLVYIVPRA AIFHSDDALK 310 320 330 340 350 360 ESAAMLNNMR VYGTAFLVLM VLVVFIGVRY VNKFASLFLA CVIVSILAIY AGAIKSSFAP 370 380 390 400 410 420 PHFPVCMLGN RTLSSRHIDV CSKTKEINNM TVPSKLWGFF CNSSQFFNAT CDEYFVHNNV 430 440 450 460 470 480 TSIQGIPGLA SGIITENLWS NYLPKGEIIE KPSAKSSDVL GSLNHEYVLV DITTSFTLLV 490 500 510 520 530 540 GIFFPSVTGI MAGSNRSGDL KDAQKSIPIG TILAILTTSF VYLSNVVLFG ACIEGVVLRD 550 560 570 580 590 600 KFGDAVKGNL VVGTLSWPSP WVIVIGSFFS TCGAGLQSLT GAPRLLQAIA KDNIIPFLRV 610 620 630 640 650 660 FGHSKANGEP TWALLLTAAI AELGILIASL DLVAPILSMF FLMCYLFVNL ACALQTLLRT 670 680 690 700 710 720 PNWRPRFRYY HWALSFMGMS ICLALMFISS WYYAIVAMVI AGMIYKYIEY QGAEKEWGDG 730 740 750 760 770 780 IRGLSLSAAR FALLRLEEGP PHTKNWRPQL LVLLKLDEDL HVKHPRLLTF ASQLKAGKGL 790 800 810 820 830 840 TIVGSVIVGN FLENYGEALA AEQTIKHLME AEKVKGFCQL VVAAKLREGI SHLIQSCGLG 850 860 870 880 890 900 GMKHNTVVMG WPNGWRQSED ARAWKTFIGT VRVTTAAHLA LLVAKNISFF PSNVEQFSEG 910 920 930 940 950 960 NIDVWWIVHD GGMLMLLPFL LKQHKVWRKC SIRIFTVAQL EDNSIQMKKD LATFLYHLRI 970 980 990 1000 1010 1020 EAEVEVVEMH DSDISAYTYE RTLMMEQRSQ MLRHMRLSKT ERDREAQLVK DRNSMLRLTS 1030 1040 1050 1060 1070 1080 IGSDEDEETE TYQEKVHMTW TKDKYMASRG QKAKSMEGFQ DLLNMRPDQS NVRRMHTAVK 1090 1100 1110 1120 1130 1140 LNEVIVNKSH EAKLVLLNMP GPPRNPEGDE NYMEFLEVLT EGLERVLLVR GGGSEVITIY S

References

[1]	"NH2-terminal heterogeneity in the KCC3 K+-Cl- cotransporter." Mercado A., Vazquez N., Song L., Cortes R., Enck A.H., Welch R., Delpire E., Gamba G., Mount D.B. Am. J. Physiol. Renal Physiol. 289:F1246-F1261(2005) [PubMed: 16048901] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	DQ138323 mRNA. Translation: ABA02873.1.
RefSeq	NP_001035961.1.
UniGene	Hs.510939
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000140199. Homo sapiens. [Contig view]
GeneID	9990.
Organism-specific databases
HGNC	HGNC:10914. SLC12A6.
GeneCards	Search...
Phylogenomic databases
HOVERGEN	Q2VI00.
Gene expression databases
ArrayExpress	Q2VI00.
Family and domain databases
InterPro	IPR000076. KCL_cotranspt. IPR000622. KCl_cotranspt1. IPR004842. NaKCl_cotransptS. IPR004841. Permease_region. [Graphical view]
Pfam	PF00324. AA_permease. 1 hit. PF03522. KCl_Cotrans_1. 1 hit. [Graphical view]
PRINTS	PR01081. KCLTRNSPORT.
TIGRFAMs	TIGR00930. 2a30. 1 hit.
Other Resources
NextBio	37729.

Entry information

Entry name

Q2VI00_HUMAN

Accession

Primary (citable) accession number: Q2VI00

Entry history

Integrated into UniProtKB/TrEMBL:	January 10, 2006
Last sequence update:	January 10, 2006
Last modified:	November 4, 2008
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)