Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

SPX domain-containing membrane protein At1g63010

Gene

At1g63010

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Protein family/group databases

TCDBi2.A.1.2.61. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
SPX domain-containing membrane protein At1g63010
Gene namesi
Ordered Locus Names:At1g63010
ORF Names:F16M19.18, F16P17.18
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G63010.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei247 – 26721HelicalSequence analysisAdd
BLAST
Transmembranei278 – 29821HelicalSequence analysisAdd
BLAST
Transmembranei315 – 33521HelicalSequence analysisAdd
BLAST
Transmembranei337 – 35620HelicalSequence analysisAdd
BLAST
Transmembranei375 – 39521HelicalSequence analysisAdd
BLAST
Transmembranei411 – 43121HelicalSequence analysisAdd
BLAST
Transmembranei513 – 53321HelicalSequence analysisAdd
BLAST
Transmembranei544 – 56421HelicalSequence analysisAdd
BLAST
Transmembranei576 – 59621HelicalSequence analysisAdd
BLAST
Transmembranei604 – 62421HelicalSequence analysisAdd
BLAST
Transmembranei670 – 69021HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Vacuole

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 697697SPX domain-containing membrane protein At1g63010PRO_0000300104Add
BLAST

Proteomic databases

PaxDbiQ2V4F9.
PRIDEiQ2V4F9.

Expressioni

Gene expression databases

ExpressionAtlasiQ2V4F9. baseline and differential.
GenevisibleiQ2V4F9. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G63010.5.

Structurei

3D structure databases

ProteinModelPortaliQ2V4F9.
SMRiQ2V4F9. Positions 254-416.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 145144SPXPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the major facilitator superfamily.Curated
Contains 1 SPX domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1161. Eukaryota.
KOG2325. Eukaryota.
ENOG41101S9. LUCA.
HOGENOMiHOG000239348.
InParanoidiQ2V4F9.
PhylomeDBiQ2V4F9.

Family and domain databases

InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR004331. SPX_dom.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
PF03105. SPX. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 2 hits.
PROSITEiPS51382. SPX. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

This entry describes 1 isoform i produced by alternative splicing. AlignAdd to basket

Note: A number of isoforms are produced. According to EST sequences.

Isoform 1 (identifier: Q2V4F9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MVAFGKYLQR KQIEEWSGYY INYKLMKKKV KQYAEQIQGG SQHPRHVLKD
60 70 80 90 100
FSRMLDTQIE TTVLFMLEQQ GLLSGRLAKL RESHDAILEQ PDISRIFELR
110 120 130 140 150
EAYRDVGRDL LQLLKFVELN AIGLRKILKK FDKRFGYRFA DYYVKTRANH
160 170 180 190 200
PYSQLQQVFK HVGVGAVVGA ISRNLHELQE NEGSFYSIYD QPVLPAQDPV
210 220 230 240 250
VEAINNAVDK LTFSTNFLNF LAQHALIMQD DLVTPSEDTI DERSYHFNSL
260 270 280 290 300
LLNLGNTFLY MVNTYIIVPT ADDYSMSLGA AATVCGVVIG SMAVAQVFSS
310 320 330 340 350
VYFSAWSNKS YFKPLVFSSI ALFIGNLMYA LAYDANSIAL LLLGRVCCGL
360 370 380 390 400
GSARAVNRRY ISDCVPLRIR MQASAGFVSA SALGMACGPA LAGLLQIKFK
410 420 430 440 450
FYKFTFNQST LPGWVMAVAW LFYLVWLCIS FREPLRDTED GEKNNRNETT
460 470 480 490 500
SDRVESSRVE EGLRLPLLIT SGIKPEDEEE CDESEESPED SHKPANSFIE
510 520 530 540 550
AYRLLTPSVK VQLLIYFMLK YSMEILLSES SVITSYYFSW TTSSVAIFLA
560 570 580 590 600
CLGLTVLPIN ILVGSYISNM FEDRQILLTS EIIVFLGILF SFNLFVPYTV
610 620 630 640 650
PQYVISGLIM FVAAEVLEGV NLSLLSRVMS SRLSKGTYNG GLLSTEAGTL
660 670 680 690
ARVVADATIT LGGYLGRGHL LNATLLPSLV ICIGSIVATC CTYNSLY
Length:697
Mass (Da):78,051
Last modified:January 10, 2006 - v1
Checksum:i4E044E44C8C21EC4
GO

Sequence cautioni

The sequence AAG51602.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010795 Genomic DNA. Translation: AAG51602.1. Sequence problems.
AC011000 Genomic DNA. Translation: AAF75814.1.
CP002684 Genomic DNA. Translation: AEE34037.1.
AK230262 mRNA. Translation: BAF02064.1.
AY035094 mRNA. Translation: AAK59599.1.
PIRiC96655.
RefSeqiNP_001077762.1. NM_001084293.1.
NP_001077763.1. NM_001084294.1.
NP_564807.2. NM_104979.3.
NP_974073.2. NM_202344.2. [Q2V4F9-1]
UniGeneiAt.17751.

Genome annotation databases

EnsemblPlantsiAT1G63010.2; AT1G63010.2; AT1G63010. [Q2V4F9-1]
GeneIDi842604.
KEGGiath:AT1G63010.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010795 Genomic DNA. Translation: AAG51602.1. Sequence problems.
AC011000 Genomic DNA. Translation: AAF75814.1.
CP002684 Genomic DNA. Translation: AEE34037.1.
AK230262 mRNA. Translation: BAF02064.1.
AY035094 mRNA. Translation: AAK59599.1.
PIRiC96655.
RefSeqiNP_001077762.1. NM_001084293.1.
NP_001077763.1. NM_001084294.1.
NP_564807.2. NM_104979.3.
NP_974073.2. NM_202344.2. [Q2V4F9-1]
UniGeneiAt.17751.

3D structure databases

ProteinModelPortaliQ2V4F9.
SMRiQ2V4F9. Positions 254-416.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT1G63010.5.

Protein family/group databases

TCDBi2.A.1.2.61. the major facilitator superfamily (mfs).

Proteomic databases

PaxDbiQ2V4F9.
PRIDEiQ2V4F9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G63010.2; AT1G63010.2; AT1G63010. [Q2V4F9-1]
GeneIDi842604.
KEGGiath:AT1G63010.

Organism-specific databases

TAIRiAT1G63010.

Phylogenomic databases

eggNOGiKOG1161. Eukaryota.
KOG2325. Eukaryota.
ENOG41101S9. LUCA.
HOGENOMiHOG000239348.
InParanoidiQ2V4F9.
PhylomeDBiQ2V4F9.

Miscellaneous databases

PROiQ2V4F9.

Gene expression databases

ExpressionAtlasiQ2V4F9. baseline and differential.
GenevisibleiQ2V4F9. AT.

Family and domain databases

InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR004331. SPX_dom.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
PF03105. SPX. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 2 hits.
PROSITEiPS51382. SPX. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
    Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.
    , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
    Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 54-697.
    Strain: cv. Columbia.
  5. Cited for: SUBCELLULAR LOCATION.

Entry informationi

Entry nameiSPXM1_ARATH
AccessioniPrimary (citable) accession number: Q2V4F9
Secondary accession number(s): Q94C80, Q9CAP0, Q9LQ03
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: January 10, 2006
Last modified: January 20, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.