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Protein

Uncharacterized zinc finger protein At4g06634

Gene

At4g06634

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri79 – 103C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri108 – 132C2H2-type 2PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri138 – 162C2H2-type 3PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri168 – 193C2H2-type 4PROSITE-ProRule annotationAdd BLAST26
Zinc fingeri230 – 255C2H2-type 5PROSITE-ProRule annotationAdd BLAST26

GO - Molecular functioni

  • metal ion binding Source: UniProtKB-KW
  • sequence-specific DNA binding Source: TAIR

GO - Biological processi

  • negative regulation of transcription, DNA-templated Source: TAIR
  • positive regulation of transcription, DNA-templated Source: TAIR
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized zinc finger protein At4g06634
Gene namesi
Ordered Locus Names:At4g06634
ORF Names:F8H12
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G06634.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003059421 – 387Uncharacterized zinc finger protein At4g06634Add BLAST387

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei284PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ2V3L3.

PTM databases

iPTMnetiQ2V3L3.

Expressioni

Gene expression databases

ExpressionAtlasiQ2V3L3. differential.

Interactioni

Protein-protein interaction databases

BioGridi11401. 2 interactors.
STRINGi3702.AT4G06634.1.

Structurei

3D structure databases

ProteinModelPortaliQ2V3L3.
SMRiQ2V3L3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi341 – 386Glu-richAdd BLAST46

Sequence similaritiesi

Contains 5 C2H2-type zinc fingers.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri79 – 103C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri108 – 132C2H2-type 2PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri138 – 162C2H2-type 3PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri168 – 193C2H2-type 4PROSITE-ProRule annotationAdd BLAST26
Zinc fingeri230 – 255C2H2-type 5PROSITE-ProRule annotationAdd BLAST26

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOGENOMiHOG000241156.
InParanoidiQ2V3L3.
OMAiWIKEWVP.
OrthoDBiEOG09360F4W.
PhylomeDBiQ2V3L3.

Family and domain databases

Gene3Di3.30.160.60. 5 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 5 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 5 hits.
PS50157. ZINC_FINGER_C2H2_2. 4 hits.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q2V3L3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MDHQNYQYQN PFERRPILKS KAPAVKWIKE WVPQDIVATG GKCHLHKWVT
60 70 80 90 100
EDTFSRLKEK EKEPDVPEPE PEPTTEILFL CSYDGCGKTF FDVSALRKHS
110 120 130 140 150
HIHGERQYVC DQEGCGKKFL DSSKLKRHYL IHTGERNYIC TYEGCGKAFS
160 170 180 190 200
LDFNLRSHMK THSQENYHIC PYSGCVKRYA HEYKLKNHVA AYHEKNGGGE
210 220 230 240 250
TPKYTPPAEK VLRTVKTPAT VCGPSSDRPY ACPYEGCEKA YIHEYKLKLH
260 270 280 290 300
LKREHPGHLQ EENADTPTLN KHNGNDRNEI DDGSDQDVYR KHASNGKGQT
310 320 330 340 350
HKQQSRAKPN MRTPPAKVGK KGSTSSPAKA RIAKKPWQAK ETFEEVEREE
360 370 380
EEDSEETEED RDNVEDGWRF GENNEDDDDD EETEYED
Note: Derived from EST data. No experimental confirmation available.
Length:387
Mass (Da):44,703
Last modified:January 10, 2006 - v1
Checksum:i070C11CC3A1A97E3
GO
Isoform 2 (identifier: Q2V3L3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-38: Missing.
     39-50: TGGKCHLHKWVT → MLNCIIVLLLLP

Note: Derived from EST data. No experimental confirmation available.
Show »
Length:349
Mass (Da):40,084
Checksum:i8E2BAD9E3896FE94
GO

Sequence cautioni

The sequence BAB83613 differs from that shown. Reason: Erroneous gene model prediction.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0283871 – 38Missing in isoform 2. CuratedAdd BLAST38
Alternative sequenceiVSP_02838839 – 50TGGKC…HKWVT → MLNCIIVLLLLP in isoform 2. CuratedAdd BLAST12

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB073162 Genomic DNA. Translation: BAB83613.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE82553.1.
CP002687 Genomic DNA. Translation: AEE82554.1.
RefSeqiNP_001031589.1. NM_001036512.2. [Q2V3L3-2]
NP_849323.1. NM_178992.4. [Q2V3L3-1]
UniGeneiAt.47264.

Genome annotation databases

EnsemblPlantsiAT4G06634.1; AT4G06634.1; AT4G06634. [Q2V3L3-1]
GeneIDi826093.
GrameneiAT4G06634.1; AT4G06634.1; AT4G06634.
KEGGiath:AT4G06634.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB073162 Genomic DNA. Translation: BAB83613.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE82553.1.
CP002687 Genomic DNA. Translation: AEE82554.1.
RefSeqiNP_001031589.1. NM_001036512.2. [Q2V3L3-2]
NP_849323.1. NM_178992.4. [Q2V3L3-1]
UniGeneiAt.47264.

3D structure databases

ProteinModelPortaliQ2V3L3.
SMRiQ2V3L3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi11401. 2 interactors.
STRINGi3702.AT4G06634.1.

PTM databases

iPTMnetiQ2V3L3.

Proteomic databases

PaxDbiQ2V3L3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G06634.1; AT4G06634.1; AT4G06634. [Q2V3L3-1]
GeneIDi826093.
GrameneiAT4G06634.1; AT4G06634.1; AT4G06634.
KEGGiath:AT4G06634.

Organism-specific databases

TAIRiAT4G06634.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
HOGENOMiHOG000241156.
InParanoidiQ2V3L3.
OMAiWIKEWVP.
OrthoDBiEOG09360F4W.
PhylomeDBiQ2V3L3.

Miscellaneous databases

PROiQ2V3L3.

Gene expression databases

ExpressionAtlasiQ2V3L3. differential.

Family and domain databases

Gene3Di3.30.160.60. 5 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 5 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 5 hits.
PS50157. ZINC_FINGER_C2H2_2. 4 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiY4634_ARATH
AccessioniPrimary (citable) accession number: Q2V3L3
Secondary accession number(s): Q27GJ7, Q8W3M5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: January 10, 2006
Last modified: November 30, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.