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Protein

Antisense of depressing factor protein 1

Gene

ADF1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Transcriptional repressor which negatively regulates transcription of FYV5 by binding to the promoter on the sense strand.1 Publication

Miscellaneous

Encoded by the antisense strand of the FYV5 gene.

GO - Molecular functioni

  • RNA polymerase II regulatory region DNA binding Source: SGD

GO - Biological processi

  • negative regulation of transcription from RNA polymerase II promoter Source: SGD
  • pheromone-dependent signal transduction involved in conjugation with cellular fusion Source: SGD
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciYEAST:G3O-29424-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Antisense of depressing factor protein 1
Gene namesi
Name:ADF1
Ordered Locus Names:YCL058W-A
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:YCL058W-A.
SGDiS000028518. ADF1.

Subcellular locationi

  • Nucleus 1 Publication

GO - Cellular componenti

  • nucleus Source: SGD

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002484501 – 113Antisense of depressing factor protein 1Add BLAST113

Proteomic databases

MaxQBiQ2V2Q1.
PRIDEiQ2V2Q1.

Interactioni

Protein-protein interaction databases

BioGridi37095. 209 interactors.
STRINGi4932.YCL058W-A.

Structurei

3D structure databases

ProteinModelPortaliQ2V2Q1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ADF1 family.Curated

Phylogenomic databases

InParanoidiQ2V2Q1.
OrthoDBiEOG092C4NGO.

Sequencei

Sequence statusi: Complete.

Q2V2Q1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKCSMKKKG VGKNVGVGKK VQKKRSISTA ERKRTKLQVE KLNKSSETMI
60 70 80 90 100
PTLLREASTQ EPAKLKAETT LKAEELIKDQ EKDSKVREQI RTEKSKTNDS
110
MLKQIEMISG FSL
Length:113
Mass (Da):12,739
Last modified:June 16, 2009 - v4
Checksum:i0D5F95141CB29BFF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59720 Genomic DNA. No translation available.
BK006937 Genomic DNA. Translation: DAA07427.1.
RefSeqiNP_001018031.2. NM_001184528.1.

Genome annotation databases

EnsemblFungiiYCL058W-A; YCL058W-A; YCL058W-A.
GeneIDi3289591.
KEGGisce:YCL058W-A.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiADF1_YEAST
AccessioniPrimary (citable) accession number: Q2V2Q1
Secondary accession number(s): D6VQV8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: June 16, 2009
Last modified: July 5, 2017
This is version 72 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome III
    Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names