Reviewed,
UniProtKB/Swiss-Prot Q2V057 (PROD2_RAT)
Last modified
January 19, 2010.
Version 27.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Probable proline dehydrogenase 2 EC=1.5.99.8 Alternative name(s): Probable proline oxidase 2 Proline oxidase-like protein | ||
| Gene names |
| ||
| Organism | Rattus norvegicus (Rat) | ||
| Taxonomic identifier | 10116 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus |
Protein attributes
| Sequence length | 456 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Function | Converts proline to delta-1-pyrroline-5-carboxylate Probable. |
| Catalytic activity | L-proline + acceptor = (S)-1-pyrroline-5-carboxylate + reduced acceptor. |
| Cofactor | FAD By similarity. |
| Pathway | |
| Sequence similarities | Belongs to the proline oxidase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Proline metabolism |
| Ligand | FAD Flavoprotein |
| Molecular function | Oxidoreductase |
| Gene Ontology (GO) | |
| Biological process | glutamate biosynthetic process Inferred from electronic annotation. Source: InterPro oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW proline catabolic processInferred from electronic annotation. Source: InterPro |
| Molecular function | proline dehydrogenase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 456 | 456 | Probable proline dehydrogenase 2 | PRO_0000308625 | |||
Sequences
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References
| [1] | Yang Q., Tian Y., Wallner E.I., Kanwar Y.S. Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AF222852 mRNA. Translation: AAQ13908.1. |
| IPI | IPI00205107. |
| UniGene | Rn.4247 |
3D structure databases | |
| SMR | Q2V057. Positions 79-429. |
| ModBase | Search... |
Genome annotation databases | |
| Ensembl | ENSRNOT00000028392; ENSRNOP00000028392; ENSRNOG00000020900; Rattus norvegicus. [Genome view] |
Organism-specific databases | |
| RGD | 1306761. Prodh2. |
Phylogenomic databases | |
| eggNOG | maNOG08806. |
| HOVERGEN | Q2V057. |
| InParanoid | Q2V057. |
Enzyme and pathway databases | |
| BRENDA | 1.5.99.8. 248. |
Gene expression databases | |
| ArrayExpress | Q2V057. |
| Genevestigator | Q2V057. |
Family and domain databases | |
| InterPro | IPR002872. Proline_DH. IPR015659. Proline_oxidase. [Graphical view] |
| PANTHER | PTHR13914. Proline_oxidase. 1 hit. |
| Pfam | PF01619. Pro_dh. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | PROD2_RAT | ||||||||
| Accession | Primary (citable) accession number: Q2V057 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HPI (Human Proteome Initiative) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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