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Q2UUZ1 (EGLC_ASPOR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable glucan endo-1,3-beta-glucosidase eglC

EC=3.2.1.39
Alternative name(s):
Endo-1,3-beta-glucanase eglC
Laminarinase eglC
Gene names
Name:eglC
ORF Names:AO090009000117
OrganismAspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) [Complete proteome]
Taxonomic identifier510516 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length463 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation and also function biosynthetically as a transglycosylase By similarity.

Catalytic activity

Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans.

Subcellular location

Cell membrane; Lipid-anchorGPI-anchor By similarity. Secretedcell wall By similarity. Note: Covalently-linked GPI-modified cell wall protein By similarity.

Post-translational modification

The GPI-anchor is attached to the protein in the endoplasmic reticulum and serves to target the protein to the cell surface. There, the glucosamine-inositol phospholipid moiety is cleaved off and the GPI-modified mannoprotein is covalently attached via its lipidless GPI glycan remnant to the 1,6-beta-glucan of the outer cell wall layer By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 17 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1818 Potential
Chain19 – 440422Probable glucan endo-1,3-beta-glucosidase eglC
PRO_0000395145
Propeptide441 – 46323Removed in mature form Potential
PRO_0000395146

Regions

Compositional bias309 – 448140Ser-rich

Sites

Active site1281Nucleophile By similarity
Active site2391Proton donor By similarity

Amino acid modifications

Lipidation4401GPI-anchor amidated glycine Potential
Glycosylation841N-linked (GlcNAc...) Potential
Glycosylation1831N-linked (GlcNAc...) Potential
Glycosylation3121N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q2UUZ1 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: 0D6C9932A360FDA8

FASTA46346,656
        10         20         30         40         50         60 
MQLTHLLAFA LSLATSEAAY KGFNYGATKS DGSVKSQSDF ESEFSTAKNL VGTSGFTSAR 

        70         80         90        100        110        120 
LYTMIQGGTT NSPISAIPAA IAENTSLLLG LWASGGGMDN ELAALKSAIS QYGDSFAKLV 

       130        140        150        160        170        180 
VGISVGSEDL YRASSEGEKV NAGIGIGPDD LVSFIKEVRS IISGTALSSV PIGHVDTWTA 

       190        200        210        220        230        240 
WTNGSNSAVI DAVDWLGFDG YPYFQSSMSN SISDAKSLFD DSVAKTKAVA KGKEVWITET 

       250        260        270        280        290        300 
GWPVSGSTQN LGVASLANAK TYWDEVGCPL FDETNTWWYI LQDANPTTPN PSFGVVGSTL 

       310        320        330        340        350        360 
STTPLFDLSC SNSTRPSASA SSSAAGSATP VGSAVPSGSA AVNPSSSGIV SSAVPSTTPG 

       370        380        390        400        410        420 
FTVGKGFRPS NSSAAAYYSS ASASGSAYPK FTKTASGSSA TSTTAGSSSD SSSTNSGKSS 

       430        440        450        460 
SESSSTNSGA SASSSILATG GASSVSGSVF GALVAVFAFV ATL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP007150 Genomic DNA. Translation: BAE54624.1.
RefSeqXP_001816626.1. XM_001816574.2.

3D structure databases

ProteinModelPortalQ2UUZ1.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADAORAT00003607; CADAORAP00003547; CADAORAG00003607.
GeneID5988556.
KEGGaor:AOR_1_198184.

Phylogenomic databases

eggNOGCOG5309.
HOGENOMHOG000179527.
OMATNTWWYI.
OrthoDBEOG7TBCCK.

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
SUPFAMSSF51445. SSF51445. 1 hit.
ProtoNetSearch...

Entry information

Entry nameEGLC_ASPOR
AccessionPrimary (citable) accession number: Q2UUZ1
Entry history
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: January 24, 2006
Last modified: February 19, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries