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Protein

Solute carrier family 25 member 38 homolog

Gene

AO090009000436

Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Mitochondrial carrier required for the biosynthesis of heme, possibly by facilitating 5-aminolevulinate (ALA) production. May act by importing glycine into mitochondria or by exchanging glycine for ALA across the mitochondrial inner membrane.UniRule annotation

GO - Molecular functioni

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 25 member 38 homologUniRule annotation
Gene namesi
ORF Names:AO090009000436
OrganismiAspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Taxonomic identifieri510516 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006564 Componenti: Chromosome 1

Subcellular locationi

  • Mitochondrion inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei27 – 52Helical; Name=1UniRule annotationAdd BLAST26
Transmembranei79 – 105Helical; Name=2UniRule annotationAdd BLAST27
Transmembranei139 – 164Helical; Name=3UniRule annotationAdd BLAST26
Transmembranei192 – 215Helical; Name=4UniRule annotationAdd BLAST24
Transmembranei238 – 264Helical; Name=5UniRule annotationAdd BLAST27
Transmembranei293 – 311Helical; Name=6UniRule annotationAdd BLAST19

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003789281 – 327Solute carrier family 25 member 38 homologAdd BLAST327

Structurei

3D structure databases

ProteinModelPortaliQ2UU67.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati21 – 104Solcar 1Add BLAST84
Repeati136 – 217Solcar 2Add BLAST82
Repeati234 – 318Solcar 3Add BLAST85

Sequence similaritiesi

Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. [View classification]UniRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000006978.
KOiK15118.
OMAiTVYEQMM.
OrthoDBiEOG092C3NVU.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
HAMAPiMF_03064. SLC25A38. 1 hit.
InterProiView protein in InterPro
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
IPR030847. SLC25A38.
PfamiView protein in Pfam
PF00153. Mito_carr. 3 hits.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiView protein in PROSITE
PS50920. SOLCAR. 3 hits.

Sequencei

Sequence statusi: Complete.

Q2UU67-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNSAVYAVP QVKKTSATTT SKTTFHFAAG LCSGLSSAIL LQPADLLKTR
60 70 80 90 100
VQQSQNAALL PTIKSIISSP NGIRGLWRGT LPSALRTGFG SALYFTSLNA
110 120 130 140 150
LRQGLAHTGV PVALSSASAN GKGVASSSAL PKLSNSANLA TGAAARVAAG
160 170 180 190 200
FVMMPVTVLK VRYESSYYAY GSLYSAGRDI LRTEGVRGLF AGFGATAARD
210 220 230 240 250
APYAGLYVLF YEQLKRRFAS LADSGTGDQS LKSSSSSINF VSGALAAGLA
260 270 280 290 300
TAITNPFDAV KTRLQLMPNK YGNMMRAVKL MVHEDGVRSL LGGLGLRITR
310 320
KALSSALAWT VYEELILRAE KHWATRD
Length:327
Mass (Da):34,455
Last modified:January 24, 2006 - v1
Checksum:i6A2497B0E013A362
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP007150 Genomic DNA. Translation: BAE54898.1.
RefSeqiXP_001816900.1. XM_001816848.2.

Genome annotation databases

EnsemblFungiiBAE54898; BAE54898; AO090009000436.
GeneIDi5988830.
KEGGiaor:AOR_1_718184.

Similar proteinsi

Entry informationi

Entry nameiS2538_ASPOR
AccessioniPrimary (citable) accession number: Q2UU67
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 7, 2009
Last sequence update: January 24, 2006
Last modified: June 7, 2017
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families