Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable beta-glucosidase E

Gene

bglE

Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).By similarity

Catalytic activityi

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei438 – 4381By similarity

GO - Molecular functioni

  1. beta-glucosidase activity Source: UniProtKB-EC

GO - Biological processi

  1. cellulose catabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

Enzyme and pathway databases

UniPathwayiUPA00696.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable beta-glucosidase E (EC:3.2.1.21)
Alternative name(s):
Beta-D-glucoside glucohydrolase E
Cellobiase E
Gentiobiase E
Gene namesi
Name:bglE
ORF Names:AO090009000554
OrganismiAspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Taxonomic identifieri510516 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006564: Chromosome 1

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 150150CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei151 – 17121Helical; Signal-anchor for type II membrane proteinSequence AnalysisAdd
BLAST
Topological domaini172 – 1048877ExtracellularSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10481048Probable beta-glucosidase EPRO_0000394873Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi216 – 2161N-linked (GlcNAc...)Sequence Analysis
Glycosylationi224 – 2241N-linked (GlcNAc...)Sequence Analysis
Glycosylationi410 – 4101N-linked (GlcNAc...)Sequence Analysis
Glycosylationi481 – 4811N-linked (GlcNAc...)Sequence Analysis
Glycosylationi520 – 5201N-linked (GlcNAc...)Sequence Analysis
Glycosylationi578 – 5781N-linked (GlcNAc...)Sequence Analysis
Glycosylationi895 – 8951N-linked (GlcNAc...)Sequence Analysis
Glycosylationi991 – 9911N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Interactioni

Protein-protein interaction databases

STRINGi5062.CADAORAP00003913.

Structurei

3D structure databases

ProteinModelPortaliQ2UTX5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 3 family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1472.
HOGENOMiHOG000031215.
KOiK05349.
OrthoDBiEOG7HMS8F.

Family and domain databases

Gene3Di3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProiIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR30620. PTHR30620. 1 hit.
PfamiPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSiPR00133. GLHYDRLASE3.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.

Sequencei

Sequence statusi: Complete.

Q2UTX5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPPPFRDAP SSAKSSQRYT PLHESIPEEL NDKQYSSDAD SLPLSDPSDG
60 70 80 90 100
EDDSEIRLRR VDRNGTRSNQ ATAYVPVVRK SGDVEAYFDS IAEAELELLS
110 120 130 140 150
ASRQYDGVDD DDDDSDGYGV GVKRGQRQGL LKRTHDGRTG WRTVYYSKYW
160 170 180 190 200
WRALIGVVVV LVLLVLVFLG LARSKQVGDE LDYSMIPAES WFPSPRGGAL
210 220 230 240 250
KEWAADYQKA ALLVGNMTLI EKVNITTGTG WQMGLCVGNT GPAESVHFPS
260 270 280 290 300
LCLQDGPMGI RYADHISAFP PGLTTGATWN RDLIRERGIA MGLEARLKGV
310 320 330 340 350
NVLLGPSMGP LGMMPAGGRN WEAFGSDPVL QGVAAAETIK GIQSNGVMAT
360 370 380 390 400
AKHFVMNEQE HFRQPFEWGI PTALSSNVGD RALHEVFAWP FAESIRADVA
410 420 430 440 450
SVMCAYQMVN NSHACENSKL LNGILKDELG FQGFVQSDWL AQRSGINSAL
460 470 480 490 500
GGLDMSMPGD GLHWADGKSL WGSELTRAVL NTSIPMERLN DMVTRIVAAW
510 520 530 540 550
YHLGQDQWER PPPDGEGGPN FSSWTDDQTG WWQQASVEAG DQDGGWGIVN
560 570 580 590 600
KYVDAGAGHG DIARKVAAEG IVLVKNNNNT LPLSRSPPSP YRIGIYGDDA
610 620 630 640 650
GPALGPNACP DRGCSQGTLA SGWGSGTVEF PFLVSPLEAL QGAWETEVEI
660 670 680 690 700
TPYLQNMVMP VSVQDKDLCL VFANANSGEG YIHAGGIHGD RNDLFLQKGG
710 720 730 740 750
DTLIQAVANN CAGPTVVVVH AVGPVVVESW IDLPGVDAVL FAHLPGQESG
760 770 780 790 800
NALVDVLFGD VDASGRLPYT VGKSLEDYGP GAQVLYENNA PVPQVDFLDA
810 820 830 840 850
LYIDYRYFDK FNITPRYEFG FGLSYTSFEL SKLYIKSMQW KSRLPKSRPQ
860 870 880 890 900
DQVSPPEYDT RPPVNENVLF PEGFHALSKY VYSYLPSLDG TAAANYTEYP
910 920 930 940 950
DGYDLPRQPS EAGGDLGGNP SLYEEMAKVQ VQVANTGARA GQTVVQAYVS
960 970 980 990 1000
FPSDVVEEGD LVEVPVDEKG ETVTFVPSKE QVEFPDRVLR NFTKIALEPG
1010 1020 1030 1040
EKKTVEMTLS RKDLSYWSAR QQNWVMPDGD FQIWVGQSSR DLPLHGKY
Length:1,048
Mass (Da):114,456
Last modified:June 15, 2010 - v2
Checksum:iC11B8431841623DE
GO

Sequence cautioni

The sequence BAE54990.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP007150 Genomic DNA. Translation: BAE54990.1. Sequence problems.
RefSeqiXP_001816992.2. XM_001816940.2.

Genome annotation databases

GeneIDi5988922.
KEGGiaor:AOR_1_914184.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP007150 Genomic DNA. Translation: BAE54990.1. Sequence problems.
RefSeqiXP_001816992.2. XM_001816940.2.

3D structure databases

ProteinModelPortaliQ2UTX5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5062.CADAORAP00003913.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5988922.
KEGGiaor:AOR_1_914184.

Phylogenomic databases

eggNOGiCOG1472.
HOGENOMiHOG000031215.
KOiK05349.
OrthoDBiEOG7HMS8F.

Enzyme and pathway databases

UniPathwayiUPA00696.

Family and domain databases

Gene3Di3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProiIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR30620. PTHR30620. 1 hit.
PfamiPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSiPR00133. GLHYDRLASE3.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequencing and analysis of Aspergillus oryzae."
    Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K., Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H., Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.
    , Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D., Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A., Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y., Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H., Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T., Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O., Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y., Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N., Kikuchi H.
    Nature 438:1157-1161(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 42149 / RIB 40.

Entry informationi

Entry nameiBGLE_ASPOR
AccessioniPrimary (citable) accession number: Q2UTX5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: June 15, 2010
Last modified: January 7, 2015
This is version 48 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.