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Protein

Probable alpha-fucosidase A

Gene

afcA

Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Alpha-fucosidase involved in degradation of fucosylated xyloglucans. Hydrolyzes alpha-1,2-linked fucose (By similarity).By similarity

Catalytic activityi

An alpha-L-fucoside + H2O = L-fucose + an alcohol.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Polysaccharide degradation

Protein family/group databases

CAZyiGH95. Glycoside Hydrolase Family 95.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable alpha-fucosidase A (EC:3.2.1.51)
Alternative name(s):
Alpha-L-fucoside fucohydrolase A
Gene namesi
Name:afcA
ORF Names:AO090005000382
OrganismiAspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Taxonomic identifieri510516 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006564 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 15Sequence analysisAdd BLAST15
ChainiPRO_000039470316 – 723Probable alpha-fucosidase AAdd BLAST708

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi77N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi98N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi117N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi171N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi194N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi243N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi334N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi558N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi566N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi595N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliQ2USL3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 95 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000235039.
OrthoDBiEOG092C0OYW.

Family and domain databases

InterProiView protein in InterPro
IPR008928. 6-hairpin_glycosidase-like.
IPR016518. Alpha-L-fucosidase.
IPR027414. GH95_N_dom.
PfamiView protein in Pfam
PF14498. Glyco_hyd_65N_2. 1 hit.
PIRSFiPIRSF007663. UCP007663. 1 hit.
SUPFAMiSSF48208. SSF48208. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2USL3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSLVLLGMS SLATANSLWS SKAASWDTTN EAYTLGNGKL GVMPFGEPGA
60 70 80 90 100
EKLNLNHDEL WEGGPFEVNG YRGGNPNSSM TEILSEVRDE IWKKGTGNDS
110 120 130 140 150
RLHGDTDGYG SFHSLANLTI AIDGIDKVSD YTRSLDLGTG IHTTTYSTGK
160 170 180 190 200
GKYTTDVYCS YPAQVCIYKL NSTATLSKVT IYFDQLVEES SLWNATCDSD
210 220 230 240 250
FARLRGVTQE GPPRGMTYDT IARSSIPGRC DSSTGKLAIN ARNSSSLTIV
260 270 280 290 300
IGAGTDFDGT KGTAATDYTF KGEDPAEYVE KITSSALSQS ESKLRTEHIE
310 320 330 340 350
DYSGLMSAFT LDLPDTQDST GTELSTLITN YNANKTDGDP YLEKLLFDYG
360 370 380 390 400
RHLFISSSRA NSLPPNLQGV WSPTKNAAWS GDYHANINLQ MNLWGAEATG
410 420 430 440 450
LGELTVAVFN YMEQNWMPRG AETAELLYGG AGWVTHDEMN IFGHTGSLVV
460 470 480 490 500
NPCTSPEQGP TTFGCTHWQQ LIHQVYENAI QGAEIAGETD STLLKDIKDQ
510 520 530 540 550
LPRLDKGLHI GTWGQIKEWK LPDSYDYEKE GNEHRHLSHL VGWYPGWSLS
560 570 580 590 600
SYFNGYNNAT IQSAVNTSLI SRGVGLYTNA GWEKVWRSAC WARLNNTEKA
610 620 630 640 650
HYELRLTIDQ NIGQSGLSLY SGGDTPSGAF QIDANFGYLG AVLSMLVVDM
660 670 680 690 700
PLDSTHSEDD VRTVVLGPAI PAAWAGGSVK GLRLRGGGSV DFSWDSEGLV
710 720
DKASATGVSS NVRIVNVEGT VLV
Length:723
Mass (Da):78,538
Last modified:June 15, 2010 - v2
Checksum:i8F22F67C3367E604
GO

Sequence cautioni

The sequence BAE55452 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP007151 Genomic DNA. Translation: BAE55452.1. Sequence problems.

Genome annotation databases

EnsemblFungiiBAE55452; BAE55452; AO090005000382.

Similar proteinsi

Entry informationi

Entry nameiAFCA_ASPOR
AccessioniPrimary (citable) accession number: Q2USL3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: June 15, 2010
Last modified: August 30, 2017
This is version 48 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families