Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable alpha-fucosidase A

Gene

afcA

Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Alpha-fucosidase involved in degradation of fucosylated xyloglucans. Hydrolyzes alpha-1,2-linked fucose (By similarity).By similarity

Catalytic activityi

An alpha-L-fucoside + H2O = L-fucose + an alcohol.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Polysaccharide degradation

Protein family/group databases

CAZyiGH95 Glycoside Hydrolase Family 95

Names & Taxonomyi

Protein namesi
Recommended name:
Probable alpha-fucosidase A (EC:3.2.1.51)
Alternative name(s):
Alpha-L-fucoside fucohydrolase A
Gene namesi
Name:afcA
ORF Names:AO090005000382
OrganismiAspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Taxonomic identifieri510516 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006564 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 15Sequence analysisAdd BLAST15
ChainiPRO_000039470316 – 723Probable alpha-fucosidase AAdd BLAST708

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi77N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi98N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi117N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi171N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi194N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi243N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi334N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi558N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi566N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi595N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliQ2USL3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 95 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000235039
OrthoDBiEOG092C0OYW

Family and domain databases

Gene3Di1.50.10.10, 1 hit
2.60.40.1180, 1 hit
InterProiView protein in InterPro
IPR008928 6-hairpin_glycosidase_sf
IPR012341 6hp_glycosidase-like_sf
IPR016518 Alpha-L-fucosidase
IPR027414 GH95_N_dom
IPR013780 Glyco_hydro_b
PfamiView protein in Pfam
PF14498 Glyco_hyd_65N_2, 1 hit
PIRSFiPIRSF007663 UCP007663, 1 hit
SUPFAMiSSF48208 SSF48208, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2USL3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSLVLLGMS SLATANSLWS SKAASWDTTN EAYTLGNGKL GVMPFGEPGA
60 70 80 90 100
EKLNLNHDEL WEGGPFEVNG YRGGNPNSSM TEILSEVRDE IWKKGTGNDS
110 120 130 140 150
RLHGDTDGYG SFHSLANLTI AIDGIDKVSD YTRSLDLGTG IHTTTYSTGK
160 170 180 190 200
GKYTTDVYCS YPAQVCIYKL NSTATLSKVT IYFDQLVEES SLWNATCDSD
210 220 230 240 250
FARLRGVTQE GPPRGMTYDT IARSSIPGRC DSSTGKLAIN ARNSSSLTIV
260 270 280 290 300
IGAGTDFDGT KGTAATDYTF KGEDPAEYVE KITSSALSQS ESKLRTEHIE
310 320 330 340 350
DYSGLMSAFT LDLPDTQDST GTELSTLITN YNANKTDGDP YLEKLLFDYG
360 370 380 390 400
RHLFISSSRA NSLPPNLQGV WSPTKNAAWS GDYHANINLQ MNLWGAEATG
410 420 430 440 450
LGELTVAVFN YMEQNWMPRG AETAELLYGG AGWVTHDEMN IFGHTGSLVV
460 470 480 490 500
NPCTSPEQGP TTFGCTHWQQ LIHQVYENAI QGAEIAGETD STLLKDIKDQ
510 520 530 540 550
LPRLDKGLHI GTWGQIKEWK LPDSYDYEKE GNEHRHLSHL VGWYPGWSLS
560 570 580 590 600
SYFNGYNNAT IQSAVNTSLI SRGVGLYTNA GWEKVWRSAC WARLNNTEKA
610 620 630 640 650
HYELRLTIDQ NIGQSGLSLY SGGDTPSGAF QIDANFGYLG AVLSMLVVDM
660 670 680 690 700
PLDSTHSEDD VRTVVLGPAI PAAWAGGSVK GLRLRGGGSV DFSWDSEGLV
710 720
DKASATGVSS NVRIVNVEGT VLV
Length:723
Mass (Da):78,538
Last modified:June 15, 2010 - v2
Checksum:i8F22F67C3367E604
GO

Sequence cautioni

The sequence BAE55452 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP007151 Genomic DNA Translation: BAE55452.1 Sequence problems.

Genome annotation databases

EnsemblFungiiBAE55452; BAE55452; AO090005000382

Similar proteinsi

Entry informationi

Entry nameiAFCA_ASPOR
AccessioniPrimary (citable) accession number: Q2USL3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: June 15, 2010
Last modified: March 28, 2018
This is version 50 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health