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Q2USL3 (AFCA_ASPOR) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable alpha-fucosidase A

EC=3.2.1.51
Alternative name(s):
Alpha-L-fucoside fucohydrolase A
Gene names
Name:afcA
ORF Names:AO090005000382
OrganismAspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) [Complete proteome]
Taxonomic identifier510516 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length723 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Alpha-fucosidase involved in degradation of fucosylated xyloglucans. Hydrolyzes alpha-1,2-linked fucose By similarity.

Catalytic activity

An alpha-L-fucoside + H2O = L-fucose + an alcohol.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 95 family.

Sequence caution

The sequence BAE55452.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Polysaccharide degradation
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpolysaccharide catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionalpha-L-fucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1515 Potential
Chain16 – 723708Probable alpha-fucosidase A
PRO_0000394703

Amino acid modifications

Glycosylation771N-linked (GlcNAc...) Potential
Glycosylation981N-linked (GlcNAc...) Potential
Glycosylation1171N-linked (GlcNAc...) Potential
Glycosylation1711N-linked (GlcNAc...) Potential
Glycosylation1941N-linked (GlcNAc...) Potential
Glycosylation2431N-linked (GlcNAc...) Potential
Glycosylation3341N-linked (GlcNAc...) Potential
Glycosylation5581N-linked (GlcNAc...) Potential
Glycosylation5661N-linked (GlcNAc...) Potential
Glycosylation5951N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q2USL3 [UniParc].

Last modified June 15, 2010. Version 2.
Checksum: 8F22F67C3367E604

FASTA72378,538
        10         20         30         40         50         60 
MRSLVLLGMS SLATANSLWS SKAASWDTTN EAYTLGNGKL GVMPFGEPGA EKLNLNHDEL 

        70         80         90        100        110        120 
WEGGPFEVNG YRGGNPNSSM TEILSEVRDE IWKKGTGNDS RLHGDTDGYG SFHSLANLTI 

       130        140        150        160        170        180 
AIDGIDKVSD YTRSLDLGTG IHTTTYSTGK GKYTTDVYCS YPAQVCIYKL NSTATLSKVT 

       190        200        210        220        230        240 
IYFDQLVEES SLWNATCDSD FARLRGVTQE GPPRGMTYDT IARSSIPGRC DSSTGKLAIN 

       250        260        270        280        290        300 
ARNSSSLTIV IGAGTDFDGT KGTAATDYTF KGEDPAEYVE KITSSALSQS ESKLRTEHIE 

       310        320        330        340        350        360 
DYSGLMSAFT LDLPDTQDST GTELSTLITN YNANKTDGDP YLEKLLFDYG RHLFISSSRA 

       370        380        390        400        410        420 
NSLPPNLQGV WSPTKNAAWS GDYHANINLQ MNLWGAEATG LGELTVAVFN YMEQNWMPRG 

       430        440        450        460        470        480 
AETAELLYGG AGWVTHDEMN IFGHTGSLVV NPCTSPEQGP TTFGCTHWQQ LIHQVYENAI 

       490        500        510        520        530        540 
QGAEIAGETD STLLKDIKDQ LPRLDKGLHI GTWGQIKEWK LPDSYDYEKE GNEHRHLSHL 

       550        560        570        580        590        600 
VGWYPGWSLS SYFNGYNNAT IQSAVNTSLI SRGVGLYTNA GWEKVWRSAC WARLNNTEKA 

       610        620        630        640        650        660 
HYELRLTIDQ NIGQSGLSLY SGGDTPSGAF QIDANFGYLG AVLSMLVVDM PLDSTHSEDD 

       670        680        690        700        710        720 
VRTVVLGPAI PAAWAGGSVK GLRLRGGGSV DFSWDSEGLV DKASATGVSS NVRIVNVEGT 


VLV 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP007151 Genomic DNA. Translation: BAE55452.1. Sequence problems.

3D structure databases

ProteinModelPortalQ2USL3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5062.CADAORAP00002350.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGNOG04067.
HOGENOMHOG000235039.
OrthoDBEOG77HDP8.

Family and domain databases

Gene3D2.70.98.50. 1 hit.
InterProIPR008928. 6-hairpin_glycosidase-like.
IPR016518. Alpha-L-fucosidase.
IPR027414. GH_fam_N_dom.
[Graphical view]
PfamPF14498. Glyco_hyd_65N_2. 1 hit.
[Graphical view]
PIRSFPIRSF007663. UCP007663. 1 hit.
SUPFAMSSF48208. SSF48208. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAFCA_ASPOR
AccessionPrimary (citable) accession number: Q2USL3
Entry history
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: June 15, 2010
Last modified: April 16, 2014
This is version 33 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries