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Protein

Exo-1,4-beta-xylosidase xlnD

Gene

xlnD

Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Xylan 1,4-beta-xylosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.1 Publication

Catalytic activityi

Hydrolysis of (1->4)-beta-D-xylans, to remove successive D-xylose residues from the non-reducing termini.

pH dependencei

Optimum pH is 4.0. Stable in the wide pH range of 3.0 to 7.0.1 Publication

Temperature dependencei

Stable at temperatures of up to 45 degrees Celsius and is inactivated gradually above 45 degrees Celsius.1 Publication

Pathwayi: xylan degradation

This protein is involved in the pathway xylan degradation, which is part of Glycan degradation.
View all proteins of this organism that are known to be involved in the pathway xylan degradation and in Glycan degradation.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei310 – 3101By similarity

GO - Molecular functioni

  • ferric iron binding Source: InterPro
  • xylan 1,4-beta-xylosidase activity Source: ASPGD

GO - Biological processi

  • cellular iron ion homeostasis Source: InterPro
  • iron ion transport Source: InterPro
  • xylan catabolic process Source: ASPGD
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Polysaccharide degradation, Xylan degradation

Enzyme and pathway databases

UniPathwayiUPA00114.

Protein family/group databases

CAZyiGH3. Glycoside Hydrolase Family 3.

Names & Taxonomyi

Protein namesi
Recommended name:
Exo-1,4-beta-xylosidase xlnD (EC:3.2.1.37)
Alternative name(s):
1,4-beta-D-xylan xylohydrolase xlnD
Beta-xylosidase A
Beta-xylosidase xlnD
Xylobiase xlnD
Gene namesi
Name:xlnD
Synonyms:xyl-1, xylA
ORF Names:AO090005000986
OrganismiAspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Taxonomic identifieri510516 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006564 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiFungiDB:AO090005000986.

Subcellular locationi

GO - Cellular componenti

  • cell Source: GOC
  • extracellular region Source: ASPGD
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence analysisAdd
BLAST
Chaini21 – 798778Exo-1,4-beta-xylosidase xlnDPRO_0000393291Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi23 – 231N-linked (GlcNAc...)Sequence analysis
Glycosylationi87 – 871N-linked (GlcNAc...)Sequence analysis
Glycosylationi142 – 1421N-linked (GlcNAc...)Sequence analysis
Glycosylationi237 – 2371N-linked (GlcNAc...)Sequence analysis
Glycosylationi326 – 3261N-linked (GlcNAc...)Sequence analysis
Glycosylationi391 – 3911N-linked (GlcNAc...)Sequence analysis
Glycosylationi404 – 4041N-linked (GlcNAc...)Sequence analysis
Glycosylationi443 – 4431N-linked (GlcNAc...)Sequence analysis
Glycosylationi480 – 4801N-linked (GlcNAc...)Sequence analysis
Glycosylationi522 – 5221N-linked (GlcNAc...)Sequence analysis
Glycosylationi618 – 6181N-linked (GlcNAc...)Sequence analysis
Glycosylationi645 – 6451N-linked (GlcNAc...)Sequence analysis
Glycosylationi658 – 6581N-linked (GlcNAc...)Sequence analysis
Glycosylationi685 – 6851N-linked (GlcNAc...)Sequence analysis
Glycosylationi707 – 7071N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliQ2UR38.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 3 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000031216.
KOiK15920.
OMAiHGLFYTN.
OrthoDBiEOG092C1FFP.

Family and domain databases

Gene3Di3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProiIPR002024. Bacterioferritin.
IPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR30620. PTHR30620. 1 hit.
PfamiPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
SMARTiSM01217. Fn3_like. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2UR38-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGAASIVAV LAALLPTALG QANQSYVDYN IEANPDLFSE CLETGGTSFP
60 70 80 90 100
DCESGPLSKT LVCDTSAKPH DRAAALVSLL TFEELVNNTA NTGHGAPRIG
110 120 130 140 150
LPAYQVWNEA LHGVAHADFS DAGGFSWSTS FPQPISTMAA LNRTLIHQIA
160 170 180 190 200
TIISTQGRAF MNAGRYGLDV YSPNINTFRH PVWGRGQETP GEDAYCLAST
210 220 230 240 250
YAYEYITGIQ GGVDANPLKL IATAKHYAGY DIENWDNHSR LGNDMQITQQ
260 270 280 290 300
DLAEYYTPQF LVASRDAKVH SVMCSYNAVN GVPSCSNSFF LQTLLRDTFD
310 320 330 340 350
FVEDGYVSGD CGAVYNVFNP HGYATNESSA AADSIRAGTD IDCGVSYPRH
360 370 380 390 400
FQESFHDQEV SRQDLERGVT RLYASLIRAG YFDGKTSPYR NITWSDVVST
410 420 430 440 450
NAQNLSYEAA AQSIVLLKND GILPLTSTSS STKTIALIGP WANATTQMLG
460 470 480 490 500
NYYGPAPYLI SPLQAFQDSE YKITYTIGTN TTTDPDSTSQ STALTTAKEA
510 520 530 540 550
DLIIFAGGID NTLETEAQDR SNITWPSNQL SLITKLADLG KPLIVLQMGG
560 570 580 590 600
GQVDSSALKN NKNVNALIWG GYPGQSGGQA LADIITGKRA PAARLVTTQY
610 620 630 640 650
PAEYAEVFPA IDMNLRPNGS NPGQTYMWYT GTPVYEFGHG LFYTNFTASA
660 670 680 690 700
SASSGTKNRT SFNIDEVLGR PHLGYKLVEQ MPLLNFTVDV KNTGDRVSDY
710 720 730 740 750
TAMAFVNTTA GPAPHPNKWL VGFDRLSAVE PGSAKTMVIP VTVDSLARTD
760 770 780 790
EEGNRVLYPG RYEVALNNER EVVLGFTLTG EKAVLFKWPK EEQLIAPQ
Length:798
Mass (Da):86,452
Last modified:January 24, 2006 - v1
Checksum:iA8BE212A0A93C5E0
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti31 – 311I → S in BAA24107 (Ref. 1) Curated
Sequence conflicti124 – 1241G → D in BAA24107 (Ref. 1) Curated
Sequence conflicti124 – 1241G → D in BAA28267 (PubMed:9872754).Curated
Sequence conflicti370 – 3701T → I in BAA24107 (Ref. 1) Curated
Sequence conflicti370 – 3701T → I in BAA28267 (PubMed:9872754).Curated
Sequence conflicti653 – 6531S → G in BAA24107 (Ref. 1) Curated
Sequence conflicti653 – 6531S → G in BAA28267 (PubMed:9872754).Curated
Sequence conflicti673 – 6731L → P in BAA24107 (Ref. 1) Curated
Sequence conflicti673 – 6731L → P in BAA28267 (PubMed:9872754).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB009972 Genomic DNA. Translation: BAA24107.1.
AB013851 Genomic DNA. Translation: BAA28267.1.
AP007151 Genomic DNA. Translation: BAE55977.1.
RefSeqiXP_001817979.1. XM_001817927.1.

Genome annotation databases

EnsemblFungiiCADAORAT00002922; CADAORAP00002875; CADAORAG00002922.
GeneIDi5990515.
KEGGiaor:AOR_1_1726174.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB009972 Genomic DNA. Translation: BAA24107.1.
AB013851 Genomic DNA. Translation: BAA28267.1.
AP007151 Genomic DNA. Translation: BAE55977.1.
RefSeqiXP_001817979.1. XM_001817927.1.

3D structure databases

ProteinModelPortaliQ2UR38.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH3. Glycoside Hydrolase Family 3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADAORAT00002922; CADAORAP00002875; CADAORAG00002922.
GeneIDi5990515.
KEGGiaor:AOR_1_1726174.

Organism-specific databases

EuPathDBiFungiDB:AO090005000986.

Phylogenomic databases

HOGENOMiHOG000031216.
KOiK15920.
OMAiHGLFYTN.
OrthoDBiEOG092C1FFP.

Enzyme and pathway databases

UniPathwayiUPA00114.

Family and domain databases

Gene3Di3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProiIPR002024. Bacterioferritin.
IPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR30620. PTHR30620. 1 hit.
PfamiPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
SMARTiSM01217. Fn3_like. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiXYND_ASPOR
AccessioniPrimary (citable) accession number: Q2UR38
Secondary accession number(s): O42698, O59862
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 23, 2010
Last sequence update: January 24, 2006
Last modified: September 7, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.