Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q2UPW4

- DAPB_ASPOR

UniProt

Q2UPW4 - DAPB_ASPOR

Protein

Probable dipeptidyl-aminopeptidase B

Gene

dapB

Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 49 (01 Oct 2014)
      Sequence version 1 (24 Jan 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.By similarity

    Catalytic activityi

    Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei740 – 7401Charge relay systemBy similarity
    Active sitei817 – 8171Charge relay systemBy similarity
    Active sitei850 – 8501Charge relay systemBy similarity

    GO - Molecular functioni

    1. aminopeptidase activity Source: UniProtKB-KW
    2. serine-type peptidase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Aminopeptidase, Hydrolase, Protease, Serine protease

    Protein family/group databases

    MEROPSiS09.006.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable dipeptidyl-aminopeptidase B (EC:3.4.14.5)
    Short name:
    DPAP B
    Gene namesi
    Name:dapB
    ORF Names:AO090005001482
    OrganismiAspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
    Taxonomic identifieri510516 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
    ProteomesiUP000006564: Chromosome 1

    Subcellular locationi

    Vacuole membrane By similarity; Single-pass type II membrane protein By similarity
    Note: Lysosome-like vacuoles.By similarity

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. vacuolar membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane, Vacuole

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 902902Probable dipeptidyl-aminopeptidase BPRO_0000412138Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi335 – 3351N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi626 – 6261N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi794 – 7941N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi799 – 7991N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Interactioni

    Protein-protein interaction databases

    STRINGi5062.CADAORAP00003299.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2UPW4.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 7878CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini100 – 902803VacuolarSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei79 – 9921Helical; Signal-anchor for type II membrane proteinSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase S9B family.Curated

    Keywords - Domaini

    Signal-anchor, Transmembrane, Transmembrane helix

    Phylogenomic databases

    HOGENOMiHOG000189891.
    OrthoDBiEOG72VHFG.

    Family and domain databases

    Gene3Di2.140.10.30. 1 hit.
    3.40.50.1820. 1 hit.
    InterProiIPR029058. AB_hydrolase.
    IPR001375. Peptidase_S9.
    IPR002469. Peptidase_S9B.
    [Graphical view]
    PfamiPF00930. DPPIV_N. 1 hit.
    PF00326. Peptidase_S9. 1 hit.
    [Graphical view]
    SUPFAMiSSF53474. SSF53474. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q2UPW4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTRRRSTSGT SSRSSTDSGL SVDTAYLEDN KHNNFANGTS GLTDETKYRD    50
    VEDAEADVDE PFLPTSSKKL GSGSRTRQIF WALVILCLGG WVLALVLFLT 100
    HGRASSQTAS ETLQQQESDS GSTSAGRPVT LQQVLTGSWN PRAHAISWIA 150
    GPDGEDGLLV QRAEVDKEGY MRVDDIRSQE GDDVDSQSGR ILIDKAAVRV 200
    NGETLMPTFT WPSPDLNKVL LMSNHEKNWR YSFTGRYWIF DVATQTAQPL 250
    DPSVPDGRVQ LALWSPSSDA VVFVRDNNMY LRKLSSESVV SITKDGGEDL 300
    FYGIPDWVYE EEVITDKSVT WWSNDGKYVA FLRTNESAVP EFPVQYFVSR 350
    PSGKRPPPGL ENYPEVRQIK YPKAGSPNPV VNLLFYDVEK DEVFPVDVPD 400
    DFPDDDRIII EVLWASEGKV IVRATNRESD RVKVFLIDTK SRTGKLVRFE 450
    DIANLDGGWV EPSHYTKFIP ADPSNGRPDD GYIDTVIHDG YDHLAYFTPL 500
    DNPDPIMLTT GEWEVVEAPS AVDLRRGIVY FVATKESPTQ RHVYRVHLDG 550
    SNLQALTDTS KPGFYDVSFS DGAGYALLSY NGPSVPWQAI INTGGDEITF 600
    EKTIEKNPRL ASMVETYALP TEIYQNVTID GFTLQLVERR PPHFNPAKKY 650
    PVVFQLYNGP TSQRVDRKFT IDFQSYIASN LGYIVVTLDA RGTGYSGRKV 700
    RCAVRGNLGH YEAHDQITTA KMWAKKPYVD ETRMAIWGWS YGGFMTLKVL 750
    EQDAGETFQY GMAVAPVTDW RFYDSVYTER YMHTPEHNPS GYENSTITNV 800
    SALSKATRFL LIHGASDDNV HIQNTLTFVD KLDLLNVQNY DMHFYPDSDH 850
    NIYFHNAHFM IYERLSNWLI NAFNGEWHQI ANPVPEDSIW DSVKRSVPAF 900
    AH 902
    Length:902
    Mass (Da):101,664
    Last modified:January 24, 2006 - v1
    Checksum:i682AE97AABC5F565
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP007151 Genomic DNA. Translation: BAE56401.1.

    Genome annotation databases

    EnsemblFungiiCADAORAT00003356; CADAORAP00003299; CADAORAG00003356.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP007151 Genomic DNA. Translation: BAE56401.1 .

    3D structure databases

    ProteinModelPortali Q2UPW4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5062.CADAORAP00003299.

    Protein family/group databases

    MEROPSi S09.006.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CADAORAT00003356 ; CADAORAP00003299 ; CADAORAG00003356 .

    Phylogenomic databases

    HOGENOMi HOG000189891.
    OrthoDBi EOG72VHFG.

    Family and domain databases

    Gene3Di 2.140.10.30. 1 hit.
    3.40.50.1820. 1 hit.
    InterProi IPR029058. AB_hydrolase.
    IPR001375. Peptidase_S9.
    IPR002469. Peptidase_S9B.
    [Graphical view ]
    Pfami PF00930. DPPIV_N. 1 hit.
    PF00326. Peptidase_S9. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53474. SSF53474. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequencing and analysis of Aspergillus oryzae."
      Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K., Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H., Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.
      , Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D., Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A., Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y., Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H., Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T., Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O., Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y., Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N., Kikuchi H.
      Nature 438:1157-1161(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 42149 / RIB 40.

    Entry informationi

    Entry nameiDAPB_ASPOR
    AccessioniPrimary (citable) accession number: Q2UPW4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 27, 2011
    Last sequence update: January 24, 2006
    Last modified: October 1, 2014
    This is version 49 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Peptidase families
      Classification of peptidase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3