Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q2UPU5 (SSU72_ASPOR) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
RNA polymerase II subunit A C-terminal domain phosphatase ssu72

Short name=CTD phosphatase ssu72
EC=3.1.3.16
Alternative name(s):
Suppressor of SUA7 protein 2 homolog
Gene names
Name:ssu72
ORF Names:AO090005001504
OrganismAspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) [Complete proteome]
Taxonomic identifier510516 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length262 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (rpb1) By similarity.

Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. Ssu72 is required for 3'-end formation of snoRNAs By similarity.

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Subunit structure

Component of the cleavage and polyadenylation factor (CPF) complex By similarity.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the SSU72 phosphatase family.

Ontologies

Keywords
   Biological processmRNA processing
   Cellular componentNucleus
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processmRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionphosphoprotein phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 262262RNA polymerase II subunit A C-terminal domain phosphatase ssu72
PRO_0000255604

Sequences

Sequence LengthMass (Da)Tools
Q2UPU5 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: ED1369D24ADB98DC

FASTA26229,311
        10         20         30         40         50         60 
MAAPTETESS DGTAAAPTQE QQSDSYKLRF CTVCASNQNR SMEAHLRLST APSPFPVISF 

        70         80         90        100        110        120 
GTGSLVRLPG PSITQPNVYN FNTTSYSQMY EELYSKDERL YRNNGLLNML ERNRNLKWGP 

       130        140        150        160        170        180 
ERFQDWVPGM PRVDHVAKGD KGALGTEGGV VDVIITCEER CWDAVVDDLM NKGSLLNRPV 

       190        200        210        220        230        240 
HVFNVDIKDN HEEALVGGKA ILELANRLNE AAVQERKANN SEGWENGTGE ARRSFDEKVP 

       250        260 
EILAAWQEKW PNLPALWTLA WL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP007151 Genomic DNA. Translation: BAE56420.1.

3D structure databases

ProteinModelPortalQ2UPU5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5062.CADAORAP00003318.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADAORAT00003375; CADAORAP00003318; CADAORAG00003375.

Phylogenomic databases

eggNOGCOG5211.
HOGENOMHOG000183445.
OrthoDBEOG7GTTG0.

Family and domain databases

InterProIPR006811. RNA_pol_II_suA.
[Graphical view]
PANTHERPTHR20383. PTHR20383. 1 hit.
PfamPF04722. Ssu72. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSSU72_ASPOR
AccessionPrimary (citable) accession number: Q2UPU5
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: January 24, 2006
Last modified: April 16, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families