Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q2UMV7

- EXGD_ASPOR

UniProt

Q2UMV7 - EXGD_ASPOR

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable glucan 1,3-beta-glucosidase D

Gene

exgD

Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Glucosidase involved in the degradation of cellulosic biomass. Active on lichenan (By similarity).By similarity

Catalytic activityi

Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1->3)-beta-D-glucans, releasing alpha-glucose.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei597 – 5971Proton donorBy similarity
Active sitei702 – 7021NucleophileBy similarity

GO - Molecular functioni

  1. glucan exo-1,3-beta-glucosidase activity Source: UniProtKB-EC

GO - Biological processi

  1. cell wall organization Source: UniProtKB-KW
  2. polysaccharide catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cell wall biogenesis/degradation, Polysaccharide degradation

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glucan 1,3-beta-glucosidase D (EC:3.2.1.58)
Alternative name(s):
Exo-1,3-beta-glucanase D
Gene namesi
Name:exgD
ORF Names:AO090001000604
OrganismiAspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Taxonomic identifieri510516 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006564: Chromosome 2

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 831831Probable glucan 1,3-beta-glucosidase DPRO_0000395166Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi376 – 3761N-linked (GlcNAc...)Sequence Analysis
Glycosylationi381 – 3811N-linked (GlcNAc...)Sequence Analysis
Glycosylationi393 – 3931N-linked (GlcNAc...)Sequence Analysis
Glycosylationi410 – 4101N-linked (GlcNAc...)Sequence Analysis
Glycosylationi442 – 4421N-linked (GlcNAc...)Sequence Analysis
Glycosylationi546 – 5461N-linked (GlcNAc...)Sequence Analysis
Glycosylationi558 – 5581N-linked (GlcNAc...)Sequence Analysis
Glycosylationi610 – 6101N-linked (GlcNAc...)Sequence Analysis
Glycosylationi636 – 6361N-linked (GlcNAc...)Sequence Analysis
Glycosylationi669 – 6691N-linked (GlcNAc...)Sequence Analysis
Glycosylationi689 – 6891N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Interactioni

Protein-protein interaction databases

STRINGi5062.CADAORAP00000542.

Structurei

3D structure databases

ProteinModelPortaliQ2UMV7.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 297297CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini319 – 831513ExtracellularSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei298 – 31821Helical; Signal-anchor for type II membrane proteinSequence AnalysisAdd
BLAST

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi6 – 161156Arg-richAdd
BLAST

Sequence similaritiesi

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG2730.
HOGENOMiHOG000114462.
KOiK01210.
OrthoDBiEOG7ZPNTV.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001547. Glyco_hydro_5.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF00150. Cellulase. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2UMV7 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPSHSRSRDR YRSERDPSRR YREVYDDDDD DDFDYHPRER RRYRRDDYQH
60 70 80 90 100
DIRSHESPNY NDDLNEYDAA AEDPAVPLRS HDVEGRRRER SRAGESPIAS
110 120 130 140 150
PSRRDRNRGG EEYRRHGTYG DGGSPTRAMR DRRHRSRDGQ RARPRDMDRE
160 170 180 190 200
ARRQRRRERA RGAAAMKHKS SDSTNSGSHL LSADALAKLR SHYDEEDQRE
210 220 230 240 250
RSQEQEQPRM ESKRQRKRPI VGDEPQALAP FPDETPRGQS KGRIVSGAYL
260 270 280 290 300
EEGHPEMEVR HRGGGGPAME ARWRKEGNWD GTMEGSDAQP PFWKRKKWWI
310 320 330 340 350
VIGVLVVVLA IVIPVAVVMS KKHGHDDDKS GSSSSVDNSD SPYISSLDGL
360 370 380 390 400
SHDSIPESAQ GSILDPWTWY DTRDFNLTFT NETVGGLPIM GLNSTWDDST
410 420 430 440 450
RPNDNVPPLN ESFPYGSQPI RGVNLGGWLS IEPFIVPSLF ENYSSKDRII
460 470 480 490 500
DEYTLCKKLG SSAASTIEKH YADFISEQDF IDMRDAGLDH VRIQFSYWAV
510 520 530 540 550
TTYDDDPYVA KISWRYLLRA IEYCRKYGLR VNLDPHGIPG SQNGWNHSGR
560 570 580 590 600
EGVIGWLNGT DGQLNRQRSL DFHNQISQFF AQPRYKNVVT IYGLVNEPLM
610 620 630 640 650
LSLPVEDVLN WTTDATKLVQ KNGISAYVTV HDGFLNLSKW KQMLKDRPDR
660 670 680 690 700
MFLDTHQYTI FNTGQIVLNH TDRVKLICND WYNMIKEINT TSAGWGPTIC
710 720 730 740 750
GEWSQADTDC AQYLNNVGRG TRWEGTFAIG DSTVYCPTAD TGPTCSCASA
760 770 780 790 800
NAPPADYSDG YKKFLQTYAE AQMSAFGTAQ GWFYWTWHTE SAAQWSYKTA
810 820 830
WKNGYMPKKA YAPDFKCGDD IPSFGDLPEY Y
Length:831
Mass (Da):95,127
Last modified:June 15, 2010 - v2
Checksum:i26359FD8943FF6DB
GO

Sequence cautioni

The sequence BAE57108.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP007154 Genomic DNA. Translation: BAE57108.1. Different initiation.
RefSeqiXP_001819110.2. XM_001819058.2.

Genome annotation databases

GeneIDi5991081.
KEGGiaor:AOR_1_1082164.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP007154 Genomic DNA. Translation: BAE57108.1 . Different initiation.
RefSeqi XP_001819110.2. XM_001819058.2.

3D structure databases

ProteinModelPortali Q2UMV7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5062.CADAORAP00000542.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 5991081.
KEGGi aor:AOR_1_1082164.

Phylogenomic databases

eggNOGi COG2730.
HOGENOMi HOG000114462.
KOi K01210.
OrthoDBi EOG7ZPNTV.

Family and domain databases

Gene3Di 3.20.20.80. 1 hit.
InterProi IPR001547. Glyco_hydro_5.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
Pfami PF00150. Cellulase. 1 hit.
[Graphical view ]
SUPFAMi SSF51445. SSF51445. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequencing and analysis of Aspergillus oryzae."
    Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K., Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H., Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.
    , Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D., Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A., Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y., Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H., Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T., Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O., Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y., Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N., Kikuchi H.
    Nature 438:1157-1161(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 42149 / RIB 40.

Entry informationi

Entry nameiEXGD_ASPOR
AccessioniPrimary (citable) accession number: Q2UMV7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: June 15, 2010
Last modified: October 29, 2014
This is version 53 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3