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Q2UMM4

- RIFK_ASPOR

UniProt

Q2UMM4 - RIFK_ASPOR

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Protein

Riboflavin kinase

Gene

fmn1

Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.By similarity

Catalytic activityi

ATP + riboflavin = ADP + FMN.

Cofactori

Zinc or magnesium.By similarity

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi44 – 441Magnesium or zincBy similarity
Active sitei101 – 1011NucleophileBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. riboflavin kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. FMN biosynthetic process Source: UniProtKB-UniPathway
  2. riboflavin biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Flavoprotein, FMN, Magnesium, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

UniPathwayiUPA00276; UER00406.

Names & Taxonomyi

Protein namesi
Recommended name:
Riboflavin kinase (EC:2.7.1.26)
Alternative name(s):
Flavin mononucleotide kinase 1
Gene namesi
Name:fmn1
ORF Names:AO090001000701
OrganismiAspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Taxonomic identifieri510516 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006564: Chromosome 2

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 198198Riboflavin kinasePRO_0000301836Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi5062.CADAORAP00000625.

Structurei

3D structure databases

ProteinModelPortaliQ2UMM4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the flavokinase family.Curated

Phylogenomic databases

eggNOGiCOG0196.
HOGENOMiHOG000260803.
KOiK00861.
OMAiINFDCEV.
OrthoDBiEOG7K3V05.

Family and domain databases

Gene3Di2.40.30.30. 1 hit.
InterProiIPR023468. Riboflavin_kinase.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
[Graphical view]
PANTHERiPTHR22749. PTHR22749. 1 hit.
PfamiPF01687. Flavokinase. 1 hit.
[Graphical view]
SMARTiSM00904. Flavokinase. 1 hit.
[Graphical view]
SUPFAMiSSF82114. SSF82114. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2UMM4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRPDGPRDPV TGPDSGPEPP FPIKLSGPVI KGFGRGSKEL GIPTANIPPD
60 70 80 90 100
GLSDYPDLQV GVYYGVVALD PSRFTSETTI LPAVLSIGYN PFYKNTTRSV
110 120 130 140 150
EIHIMPPLSS PSPTANGEAG QVKFNKLPDF YGTKLNLLIL GYIRPEYDYV
160 170 180 190
SLEALVEDIR IDCEVARQSL QRKAYVSYLS GQDCSEAVQE QRKWLTSF
Length:198
Mass (Da):21,754
Last modified:January 24, 2006 - v1
Checksum:i680B4CC0FA4C56B2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP007154 Genomic DNA. Translation: BAE57191.1.
RefSeqiXP_001819193.1. XM_001819141.1.

Genome annotation databases

EnsemblFungiiCADAORAT00000637; CADAORAP00000625; CADAORAG00000637.
GeneIDi5991164.
KEGGiaor:AOR_1_1256164.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP007154 Genomic DNA. Translation: BAE57191.1 .
RefSeqi XP_001819193.1. XM_001819141.1.

3D structure databases

ProteinModelPortali Q2UMM4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5062.CADAORAP00000625.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CADAORAT00000637 ; CADAORAP00000625 ; CADAORAG00000637 .
GeneIDi 5991164.
KEGGi aor:AOR_1_1256164.

Phylogenomic databases

eggNOGi COG0196.
HOGENOMi HOG000260803.
KOi K00861.
OMAi INFDCEV.
OrthoDBi EOG7K3V05.

Enzyme and pathway databases

UniPathwayi UPA00276 ; UER00406 .

Family and domain databases

Gene3Di 2.40.30.30. 1 hit.
InterProi IPR023468. Riboflavin_kinase.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
[Graphical view ]
PANTHERi PTHR22749. PTHR22749. 1 hit.
Pfami PF01687. Flavokinase. 1 hit.
[Graphical view ]
SMARTi SM00904. Flavokinase. 1 hit.
[Graphical view ]
SUPFAMi SSF82114. SSF82114. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequencing and analysis of Aspergillus oryzae."
    Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K., Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H., Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.
    , Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D., Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A., Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y., Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H., Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T., Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O., Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y., Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N., Kikuchi H.
    Nature 438:1157-1161(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 42149 / RIB 40.

Entry informationi

Entry nameiRIFK_ASPOR
AccessioniPrimary (citable) accession number: Q2UMM4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: January 24, 2006
Last modified: October 1, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3