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Protein

Probable pectin lyase C

Gene

pelC

Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins (By similarity).By similarity

Catalytic activityi

Eliminative cleavage of (1->4)-alpha-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei250 – 2501Sequence analysis

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbohydrate metabolism, Cell wall biogenesis/degradation, Polysaccharide degradation

Protein family/group databases

CAZyiPL1. Polysaccharide Lyase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable pectin lyase C (EC:4.2.2.10)
Short name:
PLC
Gene namesi
Name:pelC
ORF Names:AO090012000451
OrganismiAspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Taxonomic identifieri510516 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006564 Componenti: Chromosome 4

Organism-specific databases

EuPathDBiFungiDB:AO090012000451.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence analysisAdd
BLAST
Chaini21 – 375355Probable pectin lyase CPRO_0000394350Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi83 ↔ 100By similarity
Disulfide bondi92 ↔ 220By similarity
Disulfide bondi317 ↔ 325By similarity

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliQ2UCT7.
SMRiQ2UCT7. Positions 21-375.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the polysaccharide lyase 1 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000175137.
OMAiANKECAG.
OrthoDBiEOG092C2XJ9.

Family and domain databases

Gene3Di2.160.20.10. 1 hit.
InterProiIPR002022. Amb_allergen_dom.
IPR012334. Pectin_lyas_fold.
IPR011050. Pectin_lyase_fold/virulence.
[Graphical view]
PfamiPF00544. Pec_lyase_C. 1 hit.
[Graphical view]
SMARTiSM00656. Amb_all. 1 hit.
[Graphical view]
SUPFAMiSSF51126. SSF51126. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2UCT7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKITSTIPAV LLGLAPLSAA VSVSGSAEGF ASGVTGGGDA EAQIPSDIDE
60 70 80 90 100
LKEWLTDDTP RVIVLDKEYD FTESEGTTSG TVCASWGTGS GCQKIIQDDC
110 120 130 140 150
GDSPSSQATW YTAGTTGIDV ASDKTILGDG DKGVIKGKGL RFRDGVSNII
160 170 180 190 200
VQNIEISDLN PEYVWGGDAL YFDGSDLIWI DHVTTARTGR QHYTFGYETN
210 220 230 240 250
TRITLSNNFI NGETTYSTGC DGYTYWTFEM VGEADQITLQ NNYIYMTAGR
260 270 280 290 300
SPALSGGTLL HAVNNVWEKN NGHALEGGDA GARGIFEGNA WIGVSTIVGD
310 320 330 340 350
YAGRLFNAPD SSSAGDCESA LGRACEVNAV SDSGDLTAYT DTSFFSDFSG
360 370
LTIAPATSAT DAQSSVPNNA GMGKL
Length:375
Mass (Da):39,345
Last modified:January 24, 2006 - v1
Checksum:i2F6D64A33E2EF048
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP007161 Genomic DNA. Translation: BAE60628.1.
RefSeqiXP_001727467.1. XM_001727415.1.

Genome annotation databases

EnsemblFungiiCADAORAT00006032; CADAORAP00005918; CADAORAG00006032.
GeneIDi5987941.
KEGGiaor:AOR_1_784194.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP007161 Genomic DNA. Translation: BAE60628.1.
RefSeqiXP_001727467.1. XM_001727415.1.

3D structure databases

ProteinModelPortaliQ2UCT7.
SMRiQ2UCT7. Positions 21-375.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiPL1. Polysaccharide Lyase Family 1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADAORAT00006032; CADAORAP00005918; CADAORAG00006032.
GeneIDi5987941.
KEGGiaor:AOR_1_784194.

Organism-specific databases

EuPathDBiFungiDB:AO090012000451.

Phylogenomic databases

HOGENOMiHOG000175137.
OMAiANKECAG.
OrthoDBiEOG092C2XJ9.

Family and domain databases

Gene3Di2.160.20.10. 1 hit.
InterProiIPR002022. Amb_allergen_dom.
IPR012334. Pectin_lyas_fold.
IPR011050. Pectin_lyase_fold/virulence.
[Graphical view]
PfamiPF00544. Pec_lyase_C. 1 hit.
[Graphical view]
SMARTiSM00656. Amb_all. 1 hit.
[Graphical view]
SUPFAMiSSF51126. SSF51126. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPELC_ASPOR
AccessioniPrimary (citable) accession number: Q2UCT7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 18, 2010
Last sequence update: January 24, 2006
Last modified: September 7, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.