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Protein

Hexokinase

Gene

AO090120000109

Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. hexokinase activity Source: InterPro

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
ORF Names:AO090120000109Imported
OrganismiAspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)Imported
Taxonomic identifieri510516 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006564: Chromosome 5

Interactioni

Protein-protein interaction databases

STRINGi5062.CADAORAP00011050.

Structurei

3D structure databases

ProteinModelPortaliQ2U6T0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation
Contains 1 hexokinase type-1 domain.UniRule annotation
Contains 1 hexokinase type-2 domain.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000162670.
KOiK00844.
OMAiMIPRELM.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2U6T0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSALLDEAA RIARQFDFPA EGVQRGVKEY IREIDEGLSK EGTTLSQIPT
60 70 80 90 100
FVTSVPNGTE KGLYLAVDLG GTNFRVCSVD LHGDNTFSLT QSKIMIPREL
110 120 130 140 150
MASGTSKDLF TFLARQIEAF LRIHHNEHFE AHLKRRREGN SEEDLFDLGF
160 170 180 190 200
TFSFPVRQVG INKGTLIRWT KGFNIPDAVG HDVCALLQNA LDALELPVRV
210 220 230 240 250
AALVNDTVGT LMARSYTSPG ETGTFLGAIF GTGTNGAYVE KLDKITKMAT
260 270 280 290 300
IEHSDYDKTT GEMIINAEWG SFDNHLSVLP NTVYDQQLDE ESNNPGIQMF
310 320 330 340 350
EKRVSGMFLG EILRRVLVDL HRNESLGLFK PSASSDVIVP ENSTLFRQWG
360 370 380 390 400
LDTSLLSLVE ADNSESMEPT KTALKDHLKI ERASTTDCKA VKTIVHAIGK
410 420 430 440 450
RAARLSAVPI AAILIATKKL ETDDLVDVGV DGSLVEFYPN FEGYMRDALR
460 470 480 490
EVPEVGVAGD KKVRIGISKD GSGVGAALIA LVASKEEARM KAQ
Length:493
Mass (Da):54,014
Last modified:January 24, 2006 - v1
Checksum:i25CF99D80C56658D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP007166 Genomic DNA. Translation: BAE62735.1.
RefSeqiXP_001823868.1. XM_001823816.2.

Genome annotation databases

EnsemblFungiiCADAORAT00011277; CADAORAP00011050; CADAORAG00011277.
GeneIDi5996127.
KEGGiaor:AOR_1_186094.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP007166 Genomic DNA. Translation: BAE62735.1.
RefSeqiXP_001823868.1. XM_001823816.2.

3D structure databases

ProteinModelPortaliQ2U6T0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5062.CADAORAP00011050.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADAORAT00011277; CADAORAP00011050; CADAORAG00011277.
GeneIDi5996127.
KEGGiaor:AOR_1_186094.

Phylogenomic databases

HOGENOMiHOG000162670.
KOiK00844.
OMAiMIPRELM.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequencing and analysis of Aspergillus oryzae."
    Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K., Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H., Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.
    , Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D., Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A., Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y., Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H., Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T., Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O., Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y., Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N., Kikuchi H.
    Nature 438:1157-1161(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 42149 / RIB 40Imported.

Entry informationi

Entry nameiQ2U6T0_ASPOR
AccessioniPrimary (citable) accession number: Q2U6T0
Entry historyi
Integrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: March 4, 2015
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.