Q2U492 (BTGC_ASPOR) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 1, 2013.
Version 43.
History...
Clusters with 
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Probable glucan endo-1,3-beta-glucosidase btgC EC=3.2.1.39 Alternative name(s): Endo-1,3-beta-glucanase btgC Laminarinase btgC | ||||
| Gene names |
| ||||
| Organism | Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) [Complete proteome] | ||||
| Taxonomic identifier | 510516 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus ›  |
Protein attributes
| Sequence length | 685 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Acive on laminarin and lichenan By similarity. |
| Catalytic activity | Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans. |
| Subcellular location | Cell membrane; Single-pass type II membrane protein By similarity. |
| Sequence similarities | Belongs to the glycosyl hydrolase 17 family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Carbohydrate metabolism Cell wall biogenesis/degradation Polysaccharide degradation |
| Cellular component | Cell membrane Membrane |
| Domain | Signal-anchor Transmembrane Transmembrane helix |
| Molecular function | Hydrolase |
| PTM | Glycoprotein |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological_process | polysaccharide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular_component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membraneInferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular_function | glucan endo-1,3-beta-D-glucosidase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 685 | 685 | Probable glucan endo-1,3-beta-glucosidase btgC | PRO_0000395126 | |||||
Regions | |||||||||
| Topological domain | 1 – 312 | 312 | Cytoplasmic Potential | ||||||
| Transmembrane | 313 – 333 | 21 | Helical; Signal-anchor for type II membrane protein; Potential | ||||||
| Topological domain | 334 – 685 | 352 | Extracellular Potential | ||||||
| Compositional bias | 263 – 338 | 76 | Gly-rich | ||||||
Sites | |||||||||
| Active site | 587 | 1 | Nucleophile By similarity | ||||||
| Active site | 655 | 1 | Proton donor By similarity | ||||||
Amino acid modifications | |||||||||
| Glycosylation | 405 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 428 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 456 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 632 | 1 | N-linked (GlcNAc...) Potential | ||||||
Sequences
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References
| [1] | "Genome sequencing and analysis of Aspergillus oryzae." Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K., Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H., Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.  Kikuchi H.Nature 438:1157-1161(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 42149 / RIB 40. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AP007167 Genomic DNA. Translation: BAE63623.1. |
| RefSeq | XP_001824756.1. XM_001824704.2. |
3D structure databases | |
| ProteinModelPortal | Q2U492. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblFungi | CADAORAT00006912; CADAORAP00006780; CADAORAG00006912. |
| GeneID | 5997083. |
| KEGG | aor:AOR_1_772084. |
Phylogenomic databases | |
| eggNOG | COG5309. |
| HOGENOM | HOG000173877. |
| OrthoDB | EOG4KD9WH. |
Family and domain databases | |
| Gene3D | 3.20.20.80. 1 hit. |
| InterPro | IPR013781. Glyco_hydro_catalytic_dom. IPR017853. Glycoside_hydrolase_SF. [Graphical view] |
| SUPFAM | SSF51445. Glyco_hydro_cat. 1 hit. |
| PROSITE | PS00587. GLYCOSYL_HYDROL_F17. False negative. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | BTGC_ASPOR | ||||||||
| Accession | Primary (citable) accession number: Q2U492 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Fungal Protein Annotation Program | ||||||||
Relevant documents
| Glycosyl hydrolases Classification of glycosyl hydrolase families and list of entries |
| SIMILARITY comments Index of protein domains and families |