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Protein

Probable D-xylulose kinase A

Gene

xkiA

Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Highly specific D-xylulose kinase which participates in the catabolism of xylose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway (By similarity).By similarity

Catalytic activityi

ATP + D-xylulose = ADP + D-xylulose 5-phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei95SubstrateBy similarity1
Binding sitei166SubstrateBy similarity1
Binding sitei282SubstrateBy similarity1
Binding sitei283SubstrateBy similarity1
Binding sitei365ATPBy similarity1
Binding sitei474ATPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi470 – 471ATPBy similarity2

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processCarbohydrate metabolism, Xylose metabolism
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable D-xylulose kinase A (EC:2.7.1.17)
Short name:
Xylulokinase A
Gene namesi
Name:xkiA
ORF Names:AO090020000603
OrganismiAspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Taxonomic identifieri510516 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006564 Componenti: Chromosome 6

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003935221 – 572Probable D-xylulose kinase AAdd BLAST572

Proteomic databases

PRIDEiQ2U3V4

Expressioni

Inductioni

By D-xylose, L-arabinose or L-arabitol.

Interactioni

Protein-protein interaction databases

STRINGi5062.CADAORAP00006918

Structurei

3D structure databases

ProteinModelPortaliQ2U3V4
SMRiQ2U3V4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FGGY kinase family.Curated

Phylogenomic databases

HOGENOMiHOG000174850
KOiK00854
OMAiMWVQALD
OrthoDBiEOG092C1IUM

Family and domain databases

InterProiView protein in InterPro
IPR018485 Carb_kinase_FGGY_C
IPR018484 Carb_kinase_FGGY_N
PfamiView protein in Pfam
PF02782 FGGY_C, 1 hit
PF00370 FGGY_N, 1 hit

Sequencei

Sequence statusi: Complete.

Q2U3V4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQGPLYIGFD LSTQQLKALV VNSDLKVVYV SKFDFDADSR GFPIKKGVIT
60 70 80 90 100
NEAEHEVYAP VALWLQALDG VLEGLKKQGL DFARVKGISG AGQQHGSVYW
110 120 130 140 150
GQDAERLLKE LDSGKSLEDQ LSGAFSHPYS PNWQDSSTQK ECDEFDAFLG
160 170 180 190 200
GADKLANATG SKAHHRFTGP QILRFQRKYP EVYKKTSRIS LVSSFLASLF
210 220 230 240 250
LGHIAPLDTS DVCGMNLWNI KQGAYDEKLL QLCAGPSGVE DLKRKLGAVP
260 270 280 290 300
EDGGINLGQI DRYYIERYGF SSDCTIIPAT GDNPATILAL PLRPSDAMVS
310 320 330 340 350
LGTSTTFLMS TPNYMPDPAT HFFNHPTTAG LYMFMLCYKN GGLAREHIRD
360 370 380 390 400
AINDKLGMAG DKDPWANFDK ITLETAPMGQ KKDSDPMKMG LFFPRPEIVP
410 420 430 440 450
NLRAGQWRFD YNPADGSLHE TNGGWNKPAD EARAIVESQF LSLRLRSRGL
460 470 480 490 500
TASPGQGMPA QPRRVYLVGG GSKNKAIAKV AGEILGGSDG VYKLEIGDNA
510 520 530 540 550
CALGAAYKAV WALERKDGQT FEDLIGQRWR EEDFIEKIAD GYQKGVFEKY
560 570
GAALEGFEKM ELQVLKQEGE TR
Length:572
Mass (Da):62,926
Last modified:January 24, 2006 - v1
Checksum:i3A2C8A5EEA3E92D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP007167 Genomic DNA Translation: BAE63761.1
RefSeqiXP_001824894.1, XM_001824842.2

Genome annotation databases

EnsemblFungiiBAE63761; BAE63761; AO090020000603
GeneIDi5997088
KEGGiaor:AO090020000603

Similar proteinsi

Entry informationi

Entry nameiXKS1_ASPOR
AccessioniPrimary (citable) accession number: Q2U3V4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 20, 2010
Last sequence update: January 24, 2006
Last modified: May 23, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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