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Q2U3V4 (XKS1_ASPOR) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable D-xylulose kinase A

Short name=Xylulokinase A
EC=2.7.1.17
Gene names
Name:xkiA
ORF Names:AO090020000603
OrganismAspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) [Complete proteome]
Taxonomic identifier510516 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length572 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Highly specific D-xylulose kinase which participates in the catabolism of xylose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway By similarity.

Catalytic activity

ATP + D-xylulose = ADP + D-xylulose 5-phosphate.

Subcellular location

Cytoplasm By similarity.

Induction

By D-xylose, L-arabinose or L-arabitol.

Sequence similarities

Belongs to the FGGY kinase family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Xylose metabolism
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processD-xylose metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

xylulokinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 572572Probable D-xylulose kinase A
PRO_0000393522

Regions

Nucleotide binding470 – 4712ATP By similarity

Sites

Binding site951Substrate By similarity
Binding site1661Substrate By similarity
Binding site2821Substrate By similarity
Binding site2831Substrate By similarity
Binding site3651ATP By similarity
Binding site4741ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2U3V4 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: 3A2C8A5EEA3E92D9

FASTA57262,926
        10         20         30         40         50         60 
MQGPLYIGFD LSTQQLKALV VNSDLKVVYV SKFDFDADSR GFPIKKGVIT NEAEHEVYAP 

        70         80         90        100        110        120 
VALWLQALDG VLEGLKKQGL DFARVKGISG AGQQHGSVYW GQDAERLLKE LDSGKSLEDQ 

       130        140        150        160        170        180 
LSGAFSHPYS PNWQDSSTQK ECDEFDAFLG GADKLANATG SKAHHRFTGP QILRFQRKYP 

       190        200        210        220        230        240 
EVYKKTSRIS LVSSFLASLF LGHIAPLDTS DVCGMNLWNI KQGAYDEKLL QLCAGPSGVE 

       250        260        270        280        290        300 
DLKRKLGAVP EDGGINLGQI DRYYIERYGF SSDCTIIPAT GDNPATILAL PLRPSDAMVS 

       310        320        330        340        350        360 
LGTSTTFLMS TPNYMPDPAT HFFNHPTTAG LYMFMLCYKN GGLAREHIRD AINDKLGMAG 

       370        380        390        400        410        420 
DKDPWANFDK ITLETAPMGQ KKDSDPMKMG LFFPRPEIVP NLRAGQWRFD YNPADGSLHE 

       430        440        450        460        470        480 
TNGGWNKPAD EARAIVESQF LSLRLRSRGL TASPGQGMPA QPRRVYLVGG GSKNKAIAKV 

       490        500        510        520        530        540 
AGEILGGSDG VYKLEIGDNA CALGAAYKAV WALERKDGQT FEDLIGQRWR EEDFIEKIAD 

       550        560        570 
GYQKGVFEKY GAALEGFEKM ELQVLKQEGE TR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP007167 Genomic DNA. Translation: BAE63761.1.
RefSeqXP_001824894.1. XM_001824842.2.

3D structure databases

ProteinModelPortalQ2U3V4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5062.CADAORAP00006918.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADAORAT00007055; CADAORAP00006918; CADAORAG00007055.
GeneID5997088.
KEGGaor:AOR_1_1046084.

Phylogenomic databases

eggNOGCOG1070.
HOGENOMHOG000174850.
KOK00854.
OMAAACGLNR.
OrthoDBEOG7CRTZN.

Family and domain databases

InterProIPR018485. Carb_kinase_FGGY_C.
IPR018484. Carb_kinase_FGGY_N.
[Graphical view]
PfamPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXKS1_ASPOR
AccessionPrimary (citable) accession number: Q2U3V4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 20, 2010
Last sequence update: January 24, 2006
Last modified: April 16, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families