Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q2U3V4

- XKS1_ASPOR

UniProt

Q2U3V4 - XKS1_ASPOR

Protein

Probable D-xylulose kinase A

Gene

xkiA

Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 47 (01 Oct 2014)
      Sequence version 1 (24 Jan 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Highly specific D-xylulose kinase which participates in the catabolism of xylose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway By similarity.By similarity

    Catalytic activityi

    ATP + D-xylulose = ADP + D-xylulose 5-phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei95 – 951SubstrateBy similarity
    Binding sitei166 – 1661SubstrateBy similarity
    Binding sitei282 – 2821SubstrateBy similarity
    Binding sitei283 – 2831SubstrateBy similarity
    Binding sitei365 – 3651ATPBy similarity
    Binding sitei474 – 4741ATPBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi470 – 4712ATPBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. xylulokinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. D-xylose metabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Carbohydrate metabolism, Xylose metabolism

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable D-xylulose kinase A (EC:2.7.1.17)
    Short name:
    Xylulokinase A
    Gene namesi
    Name:xkiA
    ORF Names:AO090020000603
    OrganismiAspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
    Taxonomic identifieri510516 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
    ProteomesiUP000006564: Chromosome 6

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 572572Probable D-xylulose kinase APRO_0000393522Add
    BLAST

    Expressioni

    Inductioni

    By D-xylose, L-arabinose or L-arabitol.

    Interactioni

    Protein-protein interaction databases

    STRINGi5062.CADAORAP00006918.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2U3V4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the FGGY kinase family.Curated

    Phylogenomic databases

    eggNOGiCOG1070.
    HOGENOMiHOG000174850.
    KOiK00854.
    OMAiMARAHVE.
    OrthoDBiEOG7CRTZN.

    Family and domain databases

    InterProiIPR018485. Carb_kinase_FGGY_C.
    IPR018484. Carb_kinase_FGGY_N.
    [Graphical view]
    PfamiPF02782. FGGY_C. 1 hit.
    PF00370. FGGY_N. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2U3V4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQGPLYIGFD LSTQQLKALV VNSDLKVVYV SKFDFDADSR GFPIKKGVIT    50
    NEAEHEVYAP VALWLQALDG VLEGLKKQGL DFARVKGISG AGQQHGSVYW 100
    GQDAERLLKE LDSGKSLEDQ LSGAFSHPYS PNWQDSSTQK ECDEFDAFLG 150
    GADKLANATG SKAHHRFTGP QILRFQRKYP EVYKKTSRIS LVSSFLASLF 200
    LGHIAPLDTS DVCGMNLWNI KQGAYDEKLL QLCAGPSGVE DLKRKLGAVP 250
    EDGGINLGQI DRYYIERYGF SSDCTIIPAT GDNPATILAL PLRPSDAMVS 300
    LGTSTTFLMS TPNYMPDPAT HFFNHPTTAG LYMFMLCYKN GGLAREHIRD 350
    AINDKLGMAG DKDPWANFDK ITLETAPMGQ KKDSDPMKMG LFFPRPEIVP 400
    NLRAGQWRFD YNPADGSLHE TNGGWNKPAD EARAIVESQF LSLRLRSRGL 450
    TASPGQGMPA QPRRVYLVGG GSKNKAIAKV AGEILGGSDG VYKLEIGDNA 500
    CALGAAYKAV WALERKDGQT FEDLIGQRWR EEDFIEKIAD GYQKGVFEKY 550
    GAALEGFEKM ELQVLKQEGE TR 572
    Length:572
    Mass (Da):62,926
    Last modified:January 24, 2006 - v1
    Checksum:i3A2C8A5EEA3E92D9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP007167 Genomic DNA. Translation: BAE63761.1.
    RefSeqiXP_001824894.1. XM_001824842.2.

    Genome annotation databases

    EnsemblFungiiCADAORAT00007055; CADAORAP00006918; CADAORAG00007055.
    GeneIDi5997088.
    KEGGiaor:AOR_1_1046084.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP007167 Genomic DNA. Translation: BAE63761.1 .
    RefSeqi XP_001824894.1. XM_001824842.2.

    3D structure databases

    ProteinModelPortali Q2U3V4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5062.CADAORAP00006918.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CADAORAT00007055 ; CADAORAP00006918 ; CADAORAG00007055 .
    GeneIDi 5997088.
    KEGGi aor:AOR_1_1046084.

    Phylogenomic databases

    eggNOGi COG1070.
    HOGENOMi HOG000174850.
    KOi K00854.
    OMAi MARAHVE.
    OrthoDBi EOG7CRTZN.

    Family and domain databases

    InterProi IPR018485. Carb_kinase_FGGY_C.
    IPR018484. Carb_kinase_FGGY_N.
    [Graphical view ]
    Pfami PF02782. FGGY_C. 1 hit.
    PF00370. FGGY_N. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequencing and analysis of Aspergillus oryzae."
      Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K., Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H., Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.
      , Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D., Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A., Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y., Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H., Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T., Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O., Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y., Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N., Kikuchi H.
      Nature 438:1157-1161(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 42149 / RIB 40.

    Entry informationi

    Entry nameiXKS1_ASPOR
    AccessioniPrimary (citable) accession number: Q2U3V4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 20, 2010
    Last sequence update: January 24, 2006
    Last modified: October 1, 2014
    This is version 47 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3