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Protein

Probable rhamnogalacturonate lyase A

Gene

rglA

Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Degrades the rhamnogalacturonan I (RG-I) backbone of pectin (By similarity).By similarity

Catalytic activityi

Endotype eliminative cleavage of L-alpha-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronic acid bonds of rhamnogalacturonan I domains in ramified hairy regions of pectin leaving L-rhamnopyranose at the reducing end and 4-deoxy-4,5-unsaturated D-galactopyranosyluronic acid at the non-reducing end.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
Biological processCarbohydrate metabolism, Cell wall biogenesis/degradation, Polysaccharide degradation

Protein family/group databases

CAZyiPL4 Polysaccharide Lyase Family 4

Names & Taxonomyi

Protein namesi
Recommended name:
Probable rhamnogalacturonate lyase A (EC:4.2.2.23)
Gene namesi
Name:rglA
ORF Names:AO090011000349
OrganismiAspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Taxonomic identifieri510516 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006564 Componenti: Chromosome 7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_000039436921 – 528Probable rhamnogalacturonate lyase AAdd BLAST508

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi50 ↔ 93By similarity
Disulfide bondi184 ↔ 193By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PRIDEiQ2U0Q1

Structurei

3D structure databases

ProteinModelPortaliQ2U0Q1
SMRiQ2U0Q1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the polysaccharide lyase 4 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000171008
KOiK18195
OMAiQPTGFRN
OrthoDBiEOG092C31LY

Family and domain databases

CDDicd10316 RGL4_M, 1 hit
Gene3Di2.60.120.260, 1 hit
2.70.98.10, 1 hit
InterProiView protein in InterPro
IPR013784 Carb-bd-like_fold
IPR011013 Gal_mutarotase_sf_dom
IPR008979 Galactose-bd-like_sf
IPR014718 GH-type_carb-bd
IPR029413 RG-lyase_II
IPR029411 RG-lyase_III
IPR016590 Rhamnogalacturonase_B
IPR015364 RhgB_N
PANTHERiPTHR36574 PTHR36574, 1 hit
PfamiView protein in Pfam
PF14683 CBM-like, 1 hit
PF14686 fn3_3, 1 hit
PF09284 RhgB_N, 1 hit
PIRSFiPIRSF011794 Rhamnogalacturonase_B, 1 hit
SUPFAMiSSF49452 SSF49452, 1 hit
SSF49785 SSF49785, 1 hit
SSF74650 SSF74650, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2U0Q1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSRTILFST SFLWVRVANA AFGITTSDDS YVIDAGSANP LKFTVSRSSC
60 70 80 90 100
DITSINYYGS ELQYSGTGSH IGSGLGSADV SAVEDGDYIK VTCDTDTLTQ
110 120 130 140 150
YFVVHNGDSV IHMATYTTEE PSVGELRFIA RLNSELLPNE EPFGDVSTTS
160 170 180 190 200
GGEAIEGSDV FLVDGETRSK FYSSQRFIDD QRHCVAGDAH RVCMILNQYE
210 220 230 240 250
TSSGGPFFRD INSNNGGSYN SLYWYMNSGH VQTEDRRQGL HGPYSMYFSR
260 270 280 290 300
SGTPSTDIDT SFFANLDIKG YVATDGRGTV SGTASGADSS FKWVVHWYNA
310 320 330 340 350
DAQYWTYTSS DGSFTSPAMK PGDYTMVYYQ GEYKVAETSV SVTVGSSTSK
360 370 380 390 400
DISGSVETGD TIFKIGDWDG TPTGFRNAEN QLRMHPSDSR MSSWGPLTYT
410 420 430 440 450
VGSSELTDFP MAAFKGVNDP VTIKFTATSA QTGAATLRIG TTLSFAGGRP
460 470 480 490 500
QATINDYEGS APSAPTNLNS RGVTRGAYRG LGEVYDVNIP SGTIVEGENT
510 520
ITISVISGSS GDEFLAPNFI FDCVELFQ
Length:528
Mass (Da):56,966
Last modified:January 24, 2006 - v1
Checksum:iE13D69616194B4BC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP007171 Genomic DNA Translation: BAE64864.1
RefSeqiXP_001825997.1, XM_001825945.1

Genome annotation databases

EnsemblFungiiBAE64864; BAE64864; AO090011000349
GeneIDi5998100
KEGGiaor:AO090011000349

Similar proteinsi

Entry informationi

Entry nameiRGLA_ASPOR
AccessioniPrimary (citable) accession number: Q2U0Q1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 18, 2010
Last sequence update: January 24, 2006
Last modified: May 23, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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