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Protein

Glutamate decarboxylase

Gene

AO090103000342

Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  • glutamate decarboxylase activity Source: ASPGD
  • pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  • gamma-aminobutyric acid metabolic process Source: ASPGD
  • glutamate catabolic process Source: ASPGD
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
ORF Names:AO090103000342Imported
OrganismiAspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)Imported
Taxonomic identifieri510516 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006564 Componenti: Chromosome 8

Structurei

3D structure databases

ProteinModelPortaliQ2TY91.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

KOiK01580.
OMAiRWQHARR.
OrthoDBiEOG7P2Z22.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2TY91-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVHLAQVHRN ADLDSTIKRV DSIQLENTDE DGFYSSVYGT RFATEQLPQT
60 70 80 90 100
EMPEREMPRE VAYRMIKDEL SLDGNPMLNL ASFVTTYMED EAEKLMTESF
110 120 130 140 150
SKNFIDYEEY PQSAEIQNRC VNMIARLFNA PVHSEDEHPM GTSTIGSSEA
160 170 180 190 200
IMLGTLAMKR RWQNKRKAEG KDYSRPNIVM NSAVQVCWEK AARYFDVEER
210 220 230 240 250
YVYCTEDRYV IDPQQAVDLV DENTIGICAI LGTTYTGEYE DVKAINDLLI
260 270 280 290 300
ERNIDVPIHV DAASGGFVAP FINPKLEWDF RLPKVVSINV SGHKYGLVYP
310 320 330 340 350
GVGWVVWRSP EYLPKDLIFN INYLGAEQAS FTLNFSKGAS QVIGQYYQMI
360 370 380 390 400
RLGKRGYRSI MTNITVTADF LAQELEKMGF IIMSQRRGHG LPLVAFRLPA
410 420 430 440 450
EREGQFDEFA LAHQLRERGW IVPAYTMAPN SNNLKLMRVV VREDFTKSRC
460 470 480 490 500
DALLSDIKLG LKTLGDMDKA MLDKYTQHVR THATHSHKSK HNHPHYKGET
510
HSLQGKHGKT HGVC
Length:514
Mass (Da):58,660
Last modified:April 5, 2011 - v1
Checksum:i1B10E19A93F28AA5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP007174 Genomic DNA. Translation: BAE65782.1.
RefSeqiXP_001826915.1. XM_001826863.2.

Genome annotation databases

EnsemblFungiiCADAORAT00010235; CADAORAP00010027; CADAORAG00010235.
GeneIDi5999037.
KEGGiaor:AOR_1_562034.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP007174 Genomic DNA. Translation: BAE65782.1.
RefSeqiXP_001826915.1. XM_001826863.2.

3D structure databases

ProteinModelPortaliQ2TY91.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADAORAT00010235; CADAORAP00010027; CADAORAG00010235.
GeneIDi5999037.
KEGGiaor:AOR_1_562034.

Phylogenomic databases

KOiK01580.
OMAiRWQHARR.
OrthoDBiEOG7P2Z22.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequencing and analysis of Aspergillus oryzae."
    Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K., Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H., Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.
    , Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D., Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A., Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y., Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H., Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T., Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O., Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y., Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N., Kikuchi H.
    Nature 438:1157-1161(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 42149 / RIB 40Imported.

Entry informationi

Entry nameiQ2TY91_ASPOR
AccessioniPrimary (citable) accession number: Q2TY91
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: July 22, 2015
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.