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Protein
Submitted name:

2'-5' oligoadenylate synthetase 1

Gene

OAS1

Organism
Canis familiaris (Dog) (Canis lupus familiaris)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
2'-5' oligoadenylate synthetase 1Imported
Gene namesi
Name:OAS1Imported
OrganismiCanis familiaris (Dog) (Canis lupus familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000013118.

Structurei

3D structure databases

ProteinModelPortaliQ2TJA4.
SMRiQ2TJA4. Positions 3-347.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG000994.
KOiK14216.

Family and domain databases

Gene3Di1.10.1410.20. 1 hit.
InterProiIPR006117. 2-5-oligoadenylate_synth_CS.
IPR006116. 2-5-oligoadenylate_synth_N.
IPR018952. 2-5-oligoAdlate_synth_1_dom2/C.
IPR026774. 2-5A_synthase.
IPR002934. Nucleotidyltransferase.
[Graphical view]
PANTHERiPTHR11258. PTHR11258. 1 hit.
PfamiPF01909. NTP_transf_2. 1 hit.
PF10421. OAS1_C. 1 hit.
[Graphical view]
PROSITEiPS00832. 25A_SYNTH_1. 1 hit.
PS00833. 25A_SYNTH_2. 1 hit.
PS50152. 25A_SYNTH_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2TJA4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPELKDTPAK DLDRFIENYL LPDTQFRRQV KEAIHIISTF LKERCFQGAA
60 70 80 90 100
HPVRVSKVVK GGSSGKGTTL RGRSDADLVV FLNNLKSFQE QLEKRGQFIW
110 120 130 140 150
EIKRQLEACQ REETFEVYFE VQSLQWEKPR ALSFVLKSPQ LGEGVEFDVL
160 170 180 190 200
PAFDVLGQWT NNHRPNPEVY IKLIQECENR GTEGEFSTCF TELQRDFLRQ
210 220 230 240 250
RPTKVKSLIR LVKHWYQKCK QKLGKPLPPQ YALELLTVYA WERGNHQTEF
260 270 280 290 300
ITAQGFQTVL KLVLNYQQLC IHWTKYYNFE TPIIKQYLMR QLAKPRPVIL
310 320 330 340 350
DPADPTGNVA GRDTYGWQRL AQEARVWLSY PCFKKWDGSP VGSWDVLVKP

ASSLM
Length:355
Mass (Da):41,375
Last modified:January 24, 2006 - v1
Checksum:iAC82B2E538D95181
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY863104 mRNA. Translation: AAX56077.1.
RefSeqiNP_001041596.1. NM_001048131.1.
UniGeneiCfa.21183.

Genome annotation databases

GeneIDi608778.
KEGGicfa:608778.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY863104 mRNA. Translation: AAX56077.1.
RefSeqiNP_001041596.1. NM_001048131.1.
UniGeneiCfa.21183.

3D structure databases

ProteinModelPortaliQ2TJA4.
SMRiQ2TJA4. Positions 3-347.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000013118.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi608778.
KEGGicfa:608778.

Organism-specific databases

CTDi4938.

Phylogenomic databases

HOVERGENiHBG000994.
KOiK14216.

Miscellaneous databases

NextBioi20894409.

Family and domain databases

Gene3Di1.10.1410.20. 1 hit.
InterProiIPR006117. 2-5-oligoadenylate_synth_CS.
IPR006116. 2-5-oligoadenylate_synth_N.
IPR018952. 2-5-oligoAdlate_synth_1_dom2/C.
IPR026774. 2-5A_synthase.
IPR002934. Nucleotidyltransferase.
[Graphical view]
PANTHERiPTHR11258. PTHR11258. 1 hit.
PfamiPF01909. NTP_transf_2. 1 hit.
PF10421. OAS1_C. 1 hit.
[Graphical view]
PROSITEiPS00832. 25A_SYNTH_1. 1 hit.
PS00833. 25A_SYNTH_2. 1 hit.
PS50152. 25A_SYNTH_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The mammalian 2'-5' oligoadenylate synthetase gene family: evidence for concerted evolution of paralogous Oas1 genes in Rodentia and Artiodactyla."
    Perelygin A.A., Zharkikh A.A., Scherbik S.V., Brinton M.A.
    J. Mol. Evol. 63:562-576(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: KidneyImported.

Entry informationi

Entry nameiQ2TJA4_CANFA
AccessioniPrimary (citable) accession number: Q2TJA4
Entry historyi
Integrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: June 24, 2015
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.