Q2TJA4 (Q2TJA4_CANFA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
2'-5' oligoadenylate synthetase 1 EMBL AAX56077.1

Gene names

Name:

OAS1 EMBL AAX56077.1

Organism

Canis familiaris (Dog) (Canis lupus familiaris) EMBL AAX56077.1

Taxonomic identifier

9615 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Laurasiatheria › Carnivora › Caniformia › Canidae › Canis › Canis lupus

Protein attributes

Sequence length	355 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	defense response to virus Inferred from sequence or structural similarity. Source: UniProtKB immune response Inferred from electronic annotation. Source: InterPro negative regulation of viral genome replication Inferred from sequence or structural similarity. Source: UniProtKB purine nucleotide biosynthetic process Inferred from sequence or structural similarity. Source: UniProtKB
Cellular_component	cytoplasm Inferred from sequence or structural similarity. Source: UniProtKB
Molecular_function	2'-5'-oligoadenylate synthetase activity Inferred from sequence or structural similarity. Source: UniProtKB ATP binding Inferred from electronic annotation. Source: InterPro double-stranded RNA binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2TJA4 [UniParc]. Last modified January 24, 2006. Version 1. Checksum: AC82B2E538D95181	FASTA	355	41,375
	10 20 30 40 50 60 MPELKDTPAK DLDRFIENYL LPDTQFRRQV KEAIHIISTF LKERCFQGAA HPVRVSKVVK 70 80 90 100 110 120 GGSSGKGTTL RGRSDADLVV FLNNLKSFQE QLEKRGQFIW EIKRQLEACQ REETFEVYFE 130 140 150 160 170 180 VQSLQWEKPR ALSFVLKSPQ LGEGVEFDVL PAFDVLGQWT NNHRPNPEVY IKLIQECENR 190 200 210 220 230 240 GTEGEFSTCF TELQRDFLRQ RPTKVKSLIR LVKHWYQKCK QKLGKPLPPQ YALELLTVYA 250 260 270 280 290 300 WERGNHQTEF ITAQGFQTVL KLVLNYQQLC IHWTKYYNFE TPIIKQYLMR QLAKPRPVIL 310 320 330 340 350 DPADPTGNVA GRDTYGWQRL AQEARVWLSY PCFKKWDGSP VGSWDVLVKP ASSLM

References

[1]

"The mammalian 2'-5' oligoadenylate synthetase gene family: evidence for concerted evolution of paralogous Oas1 genes in Rodentia and Artiodactyla." Perelygin A.A., Zharkikh A.A., Scherbik S.V., Brinton M.A. J. Mol. Evol. 63:562-576(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Kidney EMBL AAX56077.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY863104 mRNA. Translation: AAX56077.1.
RefSeq	NP_001041596.1. NM_001048131.1.
UniGene	Cfa.46317.
3D structure databases
ProteinModelPortal	Q2TJA4.
SMR	Q2TJA4. Positions 3-347.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	608778.
KEGG	cfa:608778.
Organism-specific databases
CTD	4938.
Phylogenomic databases
HOVERGEN	HBG000994.
KO	K14216.
Family and domain databases
Gene3D	1.10.1410.20. 1 hit.
InterPro	IPR006117. 2-5-oligoadenylate_synth_CS. IPR006116. 2-5-oligoadenylate_synth_N. IPR018952. 2-5-oligoAdlate_synth_1_dom2/C. IPR026774. 2-5A_synthase. IPR002934. Nucleotidyltransferase. [Graphical view]
PANTHER	PTHR11258. PTHR11258. 1 hit.
Pfam	PF01909. NTP_transf_2. 1 hit. PF10421. OAS1_C. 1 hit. [Graphical view]
PROSITE	PS00832. 25A_SYNTH_1. 1 hit. PS00833. 25A_SYNTH_2. 1 hit. PS50152. 25A_SYNTH_3. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	20894409.

Entry information

Entry name

Q2TJA4_CANFA

Accession

Primary (citable) accession number: Q2TJA4

Entry history

Integrated into UniProtKB/TrEMBL:	January 24, 2006
Last sequence update:	January 24, 2006
Last modified:	March 6, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)