Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Palmitoyltransferase

Gene

Zdhhc1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
Name:Zdhhc1Imported
Synonyms:LOC291967Imported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 19

Organism-specific databases

RGDi1589775. Zdhhc1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei50 – 72HelicalUniRule annotationAdd BLAST23
Transmembranei78 – 100HelicalUniRule annotationAdd BLAST23
Transmembranei175 – 199HelicalUniRule annotationAdd BLAST25
Transmembranei239 – 268HelicalUniRule annotationAdd BLAST30

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSRNOG00000017045.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000060094.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini129 – 281DHHCInterPro annotationAdd BLAST153

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1311. Eukaryota.
COG5273. LUCA.
GeneTreeiENSGT00550000074293.
HOGENOMiHOG000120122.
HOVERGENiHBG059666.
KOiK20027.
OMAiQEAKGAH.
OrthoDBiEOG091G0A1N.
TreeFamiTF317498.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF01529. DHHC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2TGK5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNICNKPSNK TAPEKNVWTA PSQDSGPSPE LQGQRSRRNG WSWPPHPLQI
60 70 80 90 100
VAWLLYLFFA VIGFGVLVPL LPHHWVPAGY ACMGAIFAGH LVVHLTAVSI
110 120 130 140 150
DPADANVRDK SYSGPLPIFN RSQHAHVIED LHCNLCDVDV SARSKHCSAC
160 170 180 190 200
NKCVCGFDHH CKWLNNCVGE RNYRLFLHSV ASALLGVLLL VLVATYVFVE
210 220 230 240 250
FFVNPMRLRT NQHFEVLKNH TDVWFVFLPA APVETQAPAI LALAALLILL
260 270 280 290 300
GLLSTALLGH LLCFHIYLMW HKLTTYEYIV QHRPAQEAKE THKELESCPR
310 320 330 340 350
KMRSIQEMEF YMRTFSHVRP EPSGQARPAA LNANPSQFLA TQGQVEPPLP
360 370 380 390 400
SSSDTLALPP RIQPQEKRKR RVYRLPRSGT MDRELRLPKL RDTGTPSRHA
410 420 430 440 450
SPSSDSTSAS PAHAGCSVDA YSSASAESME EIPVAQTRLG SAALGAPGAG
460 470 480
GRESRLALQA RLPAVFVSPS SGEPGTPEAV KMACLSGD
Length:488
Mass (Da):53,653
Last modified:January 24, 2006 - v1
Checksum:iD0349CF002D86E0C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC116220 Genomic DNA. No translation available.
AY886520 mRNA. Translation: AAX73382.1.
RefSeqiNP_001034188.1. NM_001039099.1.
XP_017456716.1. XM_017601227.1.
UniGeneiRn.41274.

Genome annotation databases

EnsembliENSRNOT00000066636; ENSRNOP00000060094; ENSRNOG00000017045.
ENSRNOT00000092844; ENSRNOP00000076042; ENSRNOG00000017045.
GeneIDi291967.
KEGGirno:291967.
UCSCiRGD:1589775. rat.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ2TGK5_RAT
AccessioniPrimary (citable) accession number: Q2TGK5
Entry historyiIntegrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: June 7, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported