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Q2TCH5 (Q2TCH5_9CNID) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
OrganismAnthomedusae sp. DC-2005 EMBL AAY40168.1
Taxonomic identifier328397 [NCBI]
Taxonomic lineageEukaryotaMetazoaCnidariaHydrozoaHydroidaAnthomedusaeunclassified Anthomedusae

Protein attributes

Sequence length237 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region209 – 2135Sulfate 5 binding PDB 3GB3 PDB 2WIQ

Sites

Metal binding931Sodium
Metal binding1071Sodium; via tele nitrogen
Binding site261Chloride 1; via amide nitrogen
Binding site931Sulfate 1
Binding site971Sulfate 2 PDB 3GB3
Binding site971Sulfate 3 PDB 3GB3
Binding site1521Sulfate 4 PDB 3GB3 PDB 2WIQ
Binding site1761Sulfate 3 PDB 3GB3
Binding site1801Sulfate 4 PDB 3GB3 PDB 2WIQ
Binding site2051Chloride 2; via amide nitrogen
Binding site2171Sulfate 2 PDB 3GB3
Binding site2171Sulfate 6 PDB 2WIQ
Binding site2241Chloride 3; via amide nitrogen
Binding site2291Sulfate 3; via amide nitrogen PDB 3GB3
Binding site2291Sulfate 7 PDB 2WIQ

Amino acid modifications

Modified residue1161Cysteine sulfenic acid (-SOH)
Modified residue2151Cysteine sulfenic acid (-SOH)

Sequences

Sequence LengthMass (Da)Tools
Q2TCH5 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: 971613C336C2C552

FASTA23726,405
        10         20         30         40         50         60 
MEGGPALFQS DMTFKIFIDG EVNGQKFTIV ADGSSKFPHG DFNVHAVCET GKLPMSWKPI 

        70         80         90        100        110        120 
CHLIQYGEPF FARYPDGISH FAQECFPEGL SIDRTVRFEN DGTMTSHHTY ELDDTCVVSR 

       130        140        150        160        170        180 
ITVNCDGFQP DGPIMRDQLV DILPNETHMF PHGPNAVRQL AFIGFTTADG GLMMGHFDSK 

       190        200        210        220        230 
MTFNGSRAIE IPGPHFVTII TKQMRDTSDK RDHVCQREVA YAHSVPRITS AIGSDED 

« Hide

References

[1]"A genetically encoded photosensitizer."
Bulina M.E., Chudakov D.M., Britanova O.V., Yanushevich Y.G., Staroverov D.B., Chepurnykh T.V., Merzlyak E.M., Shkrob M.A., Lukyanov S., Lukyanov K.A.
Nat. Biotechnol. 24:95-99(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[2]"Structural basis for the phototoxicity of the fluorescent protein KillerRed."
Carpentier P., Violot S., Blanchoin L., Bourgeois D.
FEBS Lett. 583:2839-2842(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 2-237 IN COMPLEX WITH SULFATE.
[3]"Structural basis for phototoxicity of the genetically encoded photosensitizer KillerRed."
Pletnev S., Gurskaya N.G., Pletneva N.V., Lukyanov K.A., Chudakov D.M., Martynov V.I., Popov V.O., Kovalchuk M.V., Wlodawer A., Dauter Z., Pletnev V.
J. Biol. Chem. 284:32028-32039(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS) IN COMPLEX WITH SULFATE.
[4]"Crystal structure analysis of the fluorescent protein KillerRed."
Sakai N., Takemoto K., Matsuda T., Kitago Y., Ayabe T., Nagai T.
Submitted (OCT-2009) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.90 ANGSTROMS) OF 2-237.
[5]"GFP-like phototransformation mechanisms in the cytotoxic fluorescent protein KillerRed unraveled by structural and spectroscopic investigations."
de Rosny E., Carpentier P.
J. Am. Chem. Soc. 134:18015-18021(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) OF 1-64 AND 68-237 IN COMPLEX WITH CHLORIDE; SODIUM AND SULFATE.
[6]"SuperNova, a monomeric photosensitizing fluorescent protein for chromophore-assisted light inactivation."
Takemoto K., Matsuda T., Sakai N., Fu D., Noda M., Uchiyama S., Kotera I., Arai Y., Horiuchi M., Fukui K., Ayabe T., Inagaki F., Suzuki H., Nagai T.
Sci. Rep. 3:2629-2629(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) OF 2-237.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY969116 mRNA. Translation: AAY40168.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2WIQX-ray2.00A/B2-237[»]
2WISX-ray2.35A/B2-237[»]
3A8SX-ray2.90A/B2-237[»]
3GB3X-ray1.75A/B1-237[»]
3GL4X-ray2.15A/B1-237[»]
3WCKX-ray2.30A/B/C/D/E/F/G/H2-237[»]
4B30X-ray2.10A/B1-64[»]
A/B68-237[»]
ProteinModelPortalQ2TCH5.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D2.40.155.10. 1 hit.
InterProIPR009017. GFP.
IPR011584. GFP-related.
IPR023413. GFP_like.
IPR000786. Green_fluorescent_prot.
[Graphical view]
PfamPF01353. GFP. 1 hit.
[Graphical view]
PRINTSPR01229. GFLUORESCENT.
SUPFAMSSF54511. SSF54511. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceQ2TCH5.

Entry information

Entry nameQ2TCH5_9CNID
AccessionPrimary (citable) accession number: Q2TCH5
Entry history
Integrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: June 11, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)