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Q2TCH5

- Q2TCH5_9CNID

UniProt

Q2TCH5 - Q2TCH5_9CNID

Protein
Submitted name:

KillerRed

Gene
N/A
Organism
Anthomedusae sp. DC-2005
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 1 (24 Jan 2006)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei26 – 261Chloride 1; via amide nitrogen
    Metal bindingi93 – 931SodiumImported
    Binding sitei93 – 931Sulfate 1
    Metal bindingi107 – 1071Sodium; via tele nitrogenImported
    Binding sitei205 – 2051Chloride 2; via amide nitrogen
    Binding sitei224 – 2241Chloride 3; via amide nitrogen

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. bioluminescence Source: InterPro
    2. generation of precursor metabolites and energy Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    KillerRedImported
    OrganismiAnthomedusae sp. DC-2005Imported
    Taxonomic identifieri328397 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaCnidariaHydrozoaHydroidaAnthomedusaeunclassified Anthomedusae

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei116 – 1161Cysteine sulfenic acid (-SOH)
    Modified residuei215 – 2151Cysteine sulfenic acid (-SOH)

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2WIQX-ray2.00A/B2-237[»]
    2WISX-ray2.35A/B2-237[»]
    3A8SX-ray2.90A/B2-237[»]
    3GB3X-ray1.75A/B1-237[»]
    3GL4X-ray2.15A/B1-237[»]
    3WCKX-ray2.30A/B/C/D/E/F/G/H2-237[»]
    4B30X-ray2.10A/B1-64[»]
    A/B68-237[»]
    ProteinModelPortaliQ2TCH5.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ2TCH5.

    Family & Domainsi

    Family and domain databases

    Gene3Di2.40.155.10. 1 hit.
    InterProiIPR009017. GFP.
    IPR011584. GFP-related.
    IPR023413. GFP_like.
    IPR000786. Green_fluorescent_prot.
    [Graphical view]
    PfamiPF01353. GFP. 1 hit.
    [Graphical view]
    PRINTSiPR01229. GFLUORESCENT.
    SUPFAMiSSF54511. SSF54511. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q2TCH5-1 [UniParc]FASTAAdd to Basket

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    MEGGPALFQS DMTFKIFIDG EVNGQKFTIV ADGSSKFPHG DFNVHAVCET    50
    GKLPMSWKPI CHLIQYGEPF FARYPDGISH FAQECFPEGL SIDRTVRFEN 100
    DGTMTSHHTY ELDDTCVVSR ITVNCDGFQP DGPIMRDQLV DILPNETHMF 150
    PHGPNAVRQL AFIGFTTADG GLMMGHFDSK MTFNGSRAIE IPGPHFVTII 200
    TKQMRDTSDK RDHVCQREVA YAHSVPRITS AIGSDED 237
    Length:237
    Mass (Da):26,405
    Last modified:January 24, 2006 - v1
    Checksum:i971613C336C2C552
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY969116 mRNA. Translation: AAY40168.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY969116 mRNA. Translation: AAY40168.1 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2WIQ X-ray 2.00 A/B 2-237 [» ]
    2WIS X-ray 2.35 A/B 2-237 [» ]
    3A8S X-ray 2.90 A/B 2-237 [» ]
    3GB3 X-ray 1.75 A/B 1-237 [» ]
    3GL4 X-ray 2.15 A/B 1-237 [» ]
    3WCK X-ray 2.30 A/B/C/D/E/F/G/H 2-237 [» ]
    4B30 X-ray 2.10 A/B 1-64 [» ]
    A/B 68-237 [» ]
    ProteinModelPortali Q2TCH5.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    EvolutionaryTracei Q2TCH5.

    Family and domain databases

    Gene3Di 2.40.155.10. 1 hit.
    InterProi IPR009017. GFP.
    IPR011584. GFP-related.
    IPR023413. GFP_like.
    IPR000786. Green_fluorescent_prot.
    [Graphical view ]
    Pfami PF01353. GFP. 1 hit.
    [Graphical view ]
    PRINTSi PR01229. GFLUORESCENT.
    SUPFAMi SSF54511. SSF54511. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
    2. "Structural basis for the phototoxicity of the fluorescent protein KillerRed."
      Carpentier P., Violot S., Blanchoin L., Bourgeois D.
      FEBS Lett. 583:2839-2842(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 2-237.
    3. Cited for: X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS).
    4. "Crystal structure analysis of the fluorescent protein KillerRed."
      Sakai N., Takemoto K., Matsuda T., Kitago Y., Ayabe T., Nagai T.
      Submitted (OCT-2009) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (2.90 ANGSTROMS) OF 2-237.
    5. "GFP-like phototransformation mechanisms in the cytotoxic fluorescent protein KillerRed unraveled by structural and spectroscopic investigations."
      de Rosny E., Carpentier P.
      J. Am. Chem. Soc. 134:18015-18021(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) OF 1-64 AND 68-237.
    6. "SuperNova, a monomeric photosensitizing fluorescent protein for chromophore-assisted light inactivation."
      Takemoto K., Matsuda T., Sakai N., Fu D., Noda M., Uchiyama S., Kotera I., Arai Y., Horiuchi M., Fukui K., Ayabe T., Inagaki F., Suzuki H., Nagai T.
      Sci. Rep. 3:2629-2629(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) OF 2-237.

    Entry informationi

    Entry nameiQ2TCH5_9CNID
    AccessioniPrimary (citable) accession number: Q2TCH5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 24, 2006
    Last sequence update: January 24, 2006
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3