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Q2TCH5

- Q2TCH5_9CNID

UniProt

Q2TCH5 - Q2TCH5_9CNID

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Protein
Submitted name:

KillerRed

Gene
N/A
Organism
Anthomedusae sp. DC-2005
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei26 – 261Chloride 1; via amide nitrogen
Metal bindingi93 – 931SodiumImported
Binding sitei93 – 931Sulfate 1
Metal bindingi107 – 1071Sodium; via tele nitrogenImported
Binding sitei205 – 2051Chloride 2; via amide nitrogen
Binding sitei224 – 2241Chloride 3; via amide nitrogen

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. bioluminescence Source: InterPro
  2. generation of precursor metabolites and energy Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Metal-bindingImported, SodiumImported

Names & Taxonomyi

Protein namesi
Submitted name:
KillerRedImported
OrganismiAnthomedusae sp. DC-2005Imported
Taxonomic identifieri328397 [NCBI]
Taxonomic lineageiEukaryotaMetazoaCnidariaHydrozoaHydroidaAnthomedusaeunclassified Anthomedusae

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei116 – 1161Cysteine sulfenic acid (-SOH)
Modified residuei215 – 2151Cysteine sulfenic acid (-SOH)

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2WIQX-ray2.00A/B2-237[»]
2WISX-ray2.35A/B2-237[»]
3A8SX-ray2.90A/B2-237[»]
3GB3X-ray1.75A/B1-237[»]
3GL4X-ray2.15A/B1-237[»]
3WCKX-ray2.30A/B/C/D/E/F/G/H2-237[»]
4B30X-ray2.10A/B1-64[»]
A/B68-237[»]
ProteinModelPortaliQ2TCH5.

Miscellaneous databases

EvolutionaryTraceiQ2TCH5.

Family & Domainsi

Family and domain databases

Gene3Di2.40.155.10. 1 hit.
InterProiIPR009017. GFP.
IPR011584. GFP-related.
IPR023413. GFP_like.
IPR000786. Green_fluorescent_prot.
[Graphical view]
PfamiPF01353. GFP. 1 hit.
[Graphical view]
PRINTSiPR01229. GFLUORESCENT.
SUPFAMiSSF54511. SSF54511. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2TCH5-1 [UniParc]FASTAAdd to Basket

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MEGGPALFQS DMTFKIFIDG EVNGQKFTIV ADGSSKFPHG DFNVHAVCET    50
GKLPMSWKPI CHLIQYGEPF FARYPDGISH FAQECFPEGL SIDRTVRFEN 100
DGTMTSHHTY ELDDTCVVSR ITVNCDGFQP DGPIMRDQLV DILPNETHMF 150
PHGPNAVRQL AFIGFTTADG GLMMGHFDSK MTFNGSRAIE IPGPHFVTII 200
TKQMRDTSDK RDHVCQREVA YAHSVPRITS AIGSDED 237
Length:237
Mass (Da):26,405
Last modified:January 24, 2006 - v1
Checksum:i971613C336C2C552
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY969116 mRNA. Translation: AAY40168.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY969116 mRNA. Translation: AAY40168.1 .

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2WIQ X-ray 2.00 A/B 2-237 [» ]
2WIS X-ray 2.35 A/B 2-237 [» ]
3A8S X-ray 2.90 A/B 2-237 [» ]
3GB3 X-ray 1.75 A/B 1-237 [» ]
3GL4 X-ray 2.15 A/B 1-237 [» ]
3WCK X-ray 2.30 A/B/C/D/E/F/G/H 2-237 [» ]
4B30 X-ray 2.10 A/B 1-64 [» ]
A/B 68-237 [» ]
ProteinModelPortali Q2TCH5.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei Q2TCH5.

Family and domain databases

Gene3Di 2.40.155.10. 1 hit.
InterProi IPR009017. GFP.
IPR011584. GFP-related.
IPR023413. GFP_like.
IPR000786. Green_fluorescent_prot.
[Graphical view ]
Pfami PF01353. GFP. 1 hit.
[Graphical view ]
PRINTSi PR01229. GFLUORESCENT.
SUPFAMi SSF54511. SSF54511. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
  2. "Structural basis for the phototoxicity of the fluorescent protein KillerRed."
    Carpentier P., Violot S., Blanchoin L., Bourgeois D.
    FEBS Lett. 583:2839-2842(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 2-237.
  3. Cited for: X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS).
  4. "Crystal structure analysis of the fluorescent protein KillerRed."
    Sakai N., Takemoto K., Matsuda T., Kitago Y., Ayabe T., Nagai T.
    Submitted (OCT-2009) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.90 ANGSTROMS) OF 2-237.
  5. "GFP-like phototransformation mechanisms in the cytotoxic fluorescent protein KillerRed unraveled by structural and spectroscopic investigations."
    de Rosny E., Carpentier P.
    J. Am. Chem. Soc. 134:18015-18021(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) OF 1-64 AND 68-237 IN COMPLEX WITH SODIUM.
  6. "SuperNova, a monomeric photosensitizing fluorescent protein for chromophore-assisted light inactivation."
    Takemoto K., Matsuda T., Sakai N., Fu D., Noda M., Uchiyama S., Kotera I., Arai Y., Horiuchi M., Fukui K., Ayabe T., Inagaki F., Suzuki H., Nagai T.
    Sci. Rep. 3:2629-2629(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) OF 2-237.

Entry informationi

Entry nameiQ2TCH5_9CNID
AccessioniPrimary (citable) accession number: Q2TCH5
Entry historyi
Integrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: September 3, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3

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