Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Translocon-associated protein subunit delta

Gene

SSR4

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Translocon-associated protein subunit delta
Short name:
TRAP-delta
Alternative name(s):
Signal sequence receptor subunit delta
Short name:
SSR-delta
Gene namesi
Name:SSR4
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi

Organism-specific databases

VGNCiVGNC:35322 SSR4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini25 – 143LumenalSequence analysisAdd BLAST119
Transmembranei144 – 164HelicalSequence analysisAdd BLAST21
Topological domaini165 – 172CytoplasmicSequence analysis8

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_000028495725 – 172Translocon-associated protein subunit deltaAdd BLAST148

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi25 ↔ 56By similarity
Cross-linki72Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)By similarity

Keywords - PTMi

Disulfide bond, Isopeptide bond, Ubl conjugation

Proteomic databases

PaxDbiQ2TBX5
PeptideAtlasiQ2TBX5
PRIDEiQ2TBX5

Expressioni

Gene expression databases

BgeeiENSBTAG00000021421

Interactioni

Subunit structurei

Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000028556

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAP-delta family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4088 Eukaryota
ENOG4111GCB LUCA
GeneTreeiENSGT00390000008992
HOGENOMiHOG000293353
HOVERGENiHBG002293
InParanoidiQ2TBX5
KOiK04571
OMAiGPWVNSE
OrthoDBiEOG091G0UKL
TreeFamiTF313158

Family and domain databases

InterProiView protein in InterPro
IPR008855 TRAP-delta
PANTHERiPTHR12731 PTHR12731, 1 hit
PfamiView protein in Pfam
PF05404 TRAP-delta, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2TBX5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAALASLGAL ALLLLSGLSC CSEACVEPQI TPSYYTTSDA VISTETVFIV
60 70 80 90 100
EISLTCKNRV QNMALYADVS GKQFPVTRGQ DVGRYQVSWS LDHKSAHAGT
110 120 130 140 150
YEVRFFDEES YSLLRKAQRN NEDVSVIPPL FTVSVDHRGT WNGPWVSTEV
160 170
LAAAIGLVIY YLAFSAKSHI QA
Length:172
Mass (Da):18,814
Last modified:January 24, 2006 - v1
Checksum:i11D9240C1AC4CA78
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC109500 mRNA Translation: AAI09501.1
RefSeqiNP_001033592.1, NM_001038503.2
UniGeneiBt.7288

Genome annotation databases

EnsembliENSBTAT00000028556; ENSBTAP00000028556; ENSBTAG00000021421
GeneIDi504438
KEGGibta:504438

Entry informationi

Entry nameiSSRD_BOVIN
AccessioniPrimary (citable) accession number: Q2TBX5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: January 24, 2006
Last modified: March 28, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health