Q2TAP0 (GOG7B_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Golgin subfamily A member 7B

Gene names

Name:	GOLGA7B
Synonyms:	C10orf132, C10orf133

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	167 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	May be involved in protein transport from Golgi to cell surface By similarity.
Subcellular location	Golgi apparatus membrane; Lipid-anchor By similarity.
Tissue specificity	Expressed in brain, but not in lung, nor chondrocytes. Ref.3
Miscellaneous	Shares an exon with the neighboring tail-to-tail oriented gene CRTAC1.
Sequence similarities	Belongs to the ERF4 family.

Ontologies

Keywords
Cellular component	Golgi apparatus Membrane
PTM	Lipoprotein Palmitate
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	Golgi membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 167	167	Golgin subfamily A member 7B		PRO_0000244090
Regions
	Compositional bias	142 – 158	17	Ser-rich
	Compositional bias	159 – 165	7	Poly-Gly
Amino acid modifications
	Lipidation	78	1	S-palmitoyl cysteine By similarity
	Lipidation	81	1	S-palmitoyl cysteine By similarity
Experimental info
	Sequence conflict	83	1	T → M in AAI10811. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q2TAP0 [UniParc]. Last modified June 27, 2006. Version 2. Checksum: 1DB5D42080A4A66C	FASTA	167	18,335
	10 20 30 40 50 60 MATEVHNLQE LRRSASLATK VFIQRDYSDG TICQFQTKFP PELDSRIERQ LFEETVKTLN 70 80 90 100 110 120 GFYAEAEKIG GSSYLEGCLA CATAYFIFLC METHYEKVLK KISRYIQEQN EKIFAPRGLL 130 140 150 160 LTDPVERGMR VIEISIYEDR CSSGSSSSGS SSGSGSSSGG GGGAGAR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence and comparative analysis of human chromosome 10." Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J. , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J. Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain.
[3]	"Chondrocyte secreted CRTAC1: a glycosylated extracellular matrix molecule of human articular cartilage." Steck E., Braeun J., Pelttari K., Kadel S., Kalbacher H., Richter W. Matrix Biol. 26:30-41(2007) [PubMed] [Europe PMC] [Abstract] Cited for: TISSUE SPECIFICITY, EXON SHARING WITH CRTAC1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL358938 Genomic DNA. Translation: CAI14276.1. BC110810 mRNA. Translation: AAI10811.1.
IPI	IPI00402107.
RefSeq	NP_001010917.1. NM_001010917.2.
UniGene	Hs.567524.
3D structure databases
ProteinModelPortal	Q2TAP0.
ModBase	Search...
PTM databases
PhosphoSite	Q2TAP0.
Polymorphism databases
DMDM	109821405.
Proteomic databases
PaxDb	Q2TAP0.
PRIDE	Q2TAP0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000370602; ENSP00000359634; ENSG00000155265.
GeneID	401647.
KEGG	hsa:401647.
UCSC	uc001kos.3. human.
Organism-specific databases
CTD	401647.
GeneCards	GC10P099599.
HGNC	HGNC:31668. GOLGA7B.
HPA	HPA046878.
MIM	614189. gene.
neXtProt	NX_Q2TAP0.
PharmGKB	PA164720284.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG249578.
HOGENOM	HOG000010289.
HOVERGEN	HBG054534.
InParanoid	Q2TAP0.
OMA	YNPKGLQ.
OrthoDB	EOG4VX26K.
Gene expression databases
Bgee	Q2TAP0.
CleanEx	HS_GOLGA7B.
Genevestigator	Q2TAP0.
GermOnline	ENSG00000155265. Homo sapiens.
Family and domain databases
InterPro	IPR019383. Golgin_A_7/ERF4. [Graphical view]
Pfam	PF10256. Erf4. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	401647.
NextBio	107047.
SOURCE	Search...

Entry information

Entry name

GOG7B_HUMAN

Accession

Primary (citable) accession number: Q2TAP0
Secondary accession number(s): Q5T4F5

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	June 27, 2006
Last modified:	April 3, 2013
This is version 58 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.