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Protein

Golgin subfamily A member 7B

Gene

GOLGA7B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in protein transport from Golgi to cell surface.By similarity

Miscellaneous

Shares an exon with the neighboring tail-to-tail oriented gene CRTAC1.

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Golgin subfamily A member 7B
Gene namesi
Name:GOLGA7B
Synonyms:C10orf132, C10orf133
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000155265.10
HGNCiHGNC:31668 GOLGA7B
MIMi614189 gene
neXtProtiNX_Q2TAP0

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Golgi apparatus, Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000155265
PharmGKBiPA164720284

Polymorphism and mutation databases

BioMutaiGOLGA7B
DMDMi109821405

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002440901 – 167Golgin subfamily A member 7BAdd BLAST167

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi78S-palmitoyl cysteineBy similarity1
Lipidationi81S-palmitoyl cysteineBy similarity1

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

EPDiQ2TAP0
MaxQBiQ2TAP0
PaxDbiQ2TAP0
PeptideAtlasiQ2TAP0
PRIDEiQ2TAP0
ProteomicsDBi61472

PTM databases

iPTMnetiQ2TAP0
PhosphoSitePlusiQ2TAP0
SwissPalmiQ2TAP0

Expressioni

Tissue specificityi

Expressed in brain, but not in lung, nor chondrocytes.1 Publication

Gene expression databases

BgeeiENSG00000155265
CleanExiHS_GOLGA7B
ExpressionAtlasiQ2TAP0 baseline and differential
GenevisibleiQ2TAP0 HS

Organism-specific databases

HPAiHPA046878

Interactioni

Protein-protein interaction databases

BioGridi135189, 3 interactors
IntActiQ2TAP0, 2 interactors
STRINGi9606.ENSP00000359634

Structurei

3D structure databases

ProteinModelPortaliQ2TAP0
SMRiQ2TAP0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi142 – 158Ser-richAdd BLAST17
Compositional biasi159 – 165Poly-Gly7

Sequence similaritiesi

Belongs to the ERF4 family.Curated

Phylogenomic databases

eggNOGiKOG4069 Eukaryota
ENOG4111NS1 LUCA
GeneTreeiENSGT00390000000134
HOGENOMiHOG000010289
HOVERGENiHBG054534
InParanoidiQ2TAP0
OMAiTTCQFQT
OrthoDBiEOG091G0R12
PhylomeDBiQ2TAP0
TreeFamiTF313115

Family and domain databases

InterProiView protein in InterPro
IPR019383 Golgin_A_7/ERF4
PfamiView protein in Pfam
PF10256 Erf4, 1 hit

Sequencei

Sequence statusi: Complete.

Q2TAP0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATEVHNLQE LRRSASLATK VFIQRDYSDG TICQFQTKFP PELDSRIERQ
60 70 80 90 100
LFEETVKTLN GFYAEAEKIG GSSYLEGCLA CATAYFIFLC METHYEKVLK
110 120 130 140 150
KISRYIQEQN EKIFAPRGLL LTDPVERGMR VIEISIYEDR CSSGSSSSGS
160
SSGSGSSSGG GGGAGAR
Length:167
Mass (Da):18,335
Last modified:June 27, 2006 - v2
Checksum:i1DB5D42080A4A66C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti83T → M in AAI10811 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL358938 Genomic DNA No translation available.
BC110810 mRNA Translation: AAI10811.1
CCDSiCCDS31265.1
RefSeqiNP_001010917.1, NM_001010917.2
UniGeneiHs.567524

Genome annotation databases

EnsembliENST00000370602; ENSP00000359634; ENSG00000155265
GeneIDi401647
KEGGihsa:401647
UCSCiuc001kos.4 human

Similar proteinsi

Entry informationi

Entry nameiGOG7B_HUMAN
AccessioniPrimary (citable) accession number: Q2TAP0
Secondary accession number(s): Q5T4F5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: June 27, 2006
Last modified: June 20, 2018
This is version 91 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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