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Protein

Golgin subfamily A member 7B

Gene

GOLGA7B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in protein transport from Golgi to cell surface.By similarity

Miscellaneous

Shares an exon with the neighboring tail-to-tail oriented gene CRTAC1.

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Golgin subfamily A member 7B
Gene namesi
Name:GOLGA7B
Synonyms:C10orf132, C10orf133
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000155265.10.
HGNCiHGNC:31668. GOLGA7B.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Golgi apparatus, Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000155265.
PharmGKBiPA164720284.

Polymorphism and mutation databases

BioMutaiGOLGA7B.
DMDMi109821405.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002440901 – 167Golgin subfamily A member 7BAdd BLAST167

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi78S-palmitoyl cysteineBy similarity1
Lipidationi81S-palmitoyl cysteineBy similarity1

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

MaxQBiQ2TAP0.
PaxDbiQ2TAP0.
PeptideAtlasiQ2TAP0.
PRIDEiQ2TAP0.

PTM databases

iPTMnetiQ2TAP0.
PhosphoSitePlusiQ2TAP0.
SwissPalmiQ2TAP0.

Expressioni

Tissue specificityi

Expressed in brain, but not in lung, nor chondrocytes.1 Publication

Gene expression databases

BgeeiENSG00000155265.
CleanExiHS_GOLGA7B.
ExpressionAtlasiQ2TAP0. baseline and differential.
GenevisibleiQ2TAP0. HS.

Organism-specific databases

HPAiHPA046878.

Interactioni

Protein-protein interaction databases

BioGridi135189. 3 interactors.
IntActiQ2TAP0. 2 interactors.
STRINGi9606.ENSP00000359634.

Structurei

3D structure databases

ProteinModelPortaliQ2TAP0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi142 – 158Ser-richAdd BLAST17
Compositional biasi159 – 165Poly-Gly7

Sequence similaritiesi

Belongs to the ERF4 family.Curated

Phylogenomic databases

eggNOGiKOG4069. Eukaryota.
ENOG4111NS1. LUCA.
GeneTreeiENSGT00390000000134.
HOGENOMiHOG000010289.
HOVERGENiHBG054534.
InParanoidiQ2TAP0.
OMAiNERIYNP.
OrthoDBiEOG091G0R12.
PhylomeDBiQ2TAP0.
TreeFamiTF313115.

Family and domain databases

InterProiView protein in InterPro
IPR019383. Golgin_A_7/ERF4.
PfamiView protein in Pfam
PF10256. Erf4. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2TAP0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATEVHNLQE LRRSASLATK VFIQRDYSDG TICQFQTKFP PELDSRIERQ
60 70 80 90 100
LFEETVKTLN GFYAEAEKIG GSSYLEGCLA CATAYFIFLC METHYEKVLK
110 120 130 140 150
KISRYIQEQN EKIFAPRGLL LTDPVERGMR VIEISIYEDR CSSGSSSSGS
160
SSGSGSSSGG GGGAGAR
Length:167
Mass (Da):18,335
Last modified:June 27, 2006 - v2
Checksum:i1DB5D42080A4A66C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti83T → M in AAI10811 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL358938 Genomic DNA. No translation available.
BC110810 mRNA. Translation: AAI10811.1.
CCDSiCCDS31265.1.
RefSeqiNP_001010917.1. NM_001010917.2.
UniGeneiHs.567524.

Genome annotation databases

EnsembliENST00000370602; ENSP00000359634; ENSG00000155265.
GeneIDi401647.
KEGGihsa:401647.
UCSCiuc001kos.4. human.

Similar proteinsi

Entry informationi

Entry nameiGOG7B_HUMAN
AccessioniPrimary (citable) accession number: Q2TAP0
Secondary accession number(s): Q5T4F5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: June 27, 2006
Last modified: September 27, 2017
This is version 87 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families