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Protein

Battenin

Gene

CLN3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
BatteninUniRule annotation
Gene namesi
Name:CLN3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000261832.5.
HGNCiHGNC:2074. CLN3.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei21 – 44HelicalUniRule annotationAdd BLAST24
Transmembranei50 – 67HelicalUniRule annotationAdd BLAST18
Transmembranei74 – 97HelicalUniRule annotationAdd BLAST24
Transmembranei103 – 122HelicalUniRule annotationAdd BLAST20
Transmembranei134 – 152HelicalUniRule annotationAdd BLAST19
Transmembranei203 – 220HelicalUniRule annotationAdd BLAST18
Transmembranei266 – 287HelicalUniRule annotationAdd BLAST22
Transmembranei293 – 312HelicalUniRule annotationAdd BLAST20

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000188603.
ENSG00000261832.

PTM / Processingi

Proteomic databases

MaxQBiQ2TA70.

Expressioni

Gene expression databases

BgeeiENSG00000261832.
ExpressionAtlasiQ2TA70. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000454253.

Family & Domainsi

Sequence similaritiesi

Belongs to the battenin family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG3880. Eukaryota.
ENOG410XT4Z. LUCA.
GeneTreeiENSGT00390000003249.
HOVERGENiHBG017297.
OrthoDBiEOG091G07YG.
TreeFamiTF314055.

Family and domain databases

InterProiView protein in InterPro
IPR003492. Battenin_disease_Cln3.
IPR018460. Battenin_disease_Cln3_subgr.
IPR020846. MFS_dom.
PANTHERiPTHR10981. PTHR10981. 1 hit.
PfamiView protein in Pfam
PF02487. CLN3. 1 hit.
PIRSFiPIRSF015974. CLN3_BTN1. 1 hit.
PRINTSiPR01315. BATTENIN.
SUPFAMiSSF103473. SSF103473. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2TA70-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSAAHDILS HKRTSGNQSH AVLLADILPT LVIKLLAPLG LHLLPYSPRV
60 70 80 90 100
LVSGICAAGS FVLVAFSHSV GTSLCGVVFA SISSGLGEVT FLSLTAFYPR
110 120 130 140 150
AVISWWSSGT GGAGLLGALS YLGLTQAGLS PQQTLLSMLG IPALLLASYF
160 170 180 190 200
LLLTSPEAQD PGGEEEAESA ARQPLIRTEA PESKPGSSSS LSLRERWTVF
210 220 230 240 250
KGLLWYIVPL VVVYFAEYFI NQGLFELLFF WNTSLSHAQQ YRWYQMLYQA
260 270 280 290 300
GVFASRSSLR CCRIRFTWAL ALLQCLNLVF LLADVWFGFL PSIYLVFLII
310 320 330 340 350
LYEGLLGGAA YVNTFHNIAL ETSDEHREFA MAATCISDTL GISLSGLLAL
360
PLHDFLCQLS
Length:360
Mass (Da):39,168
Last modified:January 24, 2006 - v1
Checksum:i5DB527A0503D338D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC138894 Genomic DNA. No translation available.
BC111068 mRNA. Translation: AAI11069.1.
RefSeqiNP_001273038.1. NM_001286109.1.
UniGeneiHs.534667.

Genome annotation databases

EnsembliENST00000568224; ENSP00000454253; ENSG00000261832.
ENST00000637551; ENSP00000490155; ENSG00000188603.
GeneIDi1201.
UCSCiuc002dpl.4. human.

Similar proteinsi

Entry informationi

Entry nameiQ2TA70_HUMAN
AccessioniPrimary (citable) accession number: Q2TA70
Entry historyiIntegrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: September 27, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported