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Q2T9Y5

- Q2T9Y5_BOVIN

UniProt

Q2T9Y5 - Q2T9Y5_BOVIN

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Protein
DNA ligase
Gene
LIG3
Organism
Bos taurus (Bovine)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: RefGenome
  4. zinc ion binding Source: InterPro

GO - Biological processi

  1. DNA ligation Source: RefGenome
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. lagging strand elongation Source: RefGenome
  5. nucleotide-excision repair Source: RefGenome
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Name:LIG3Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

Subcellular locationi

GO - Cellular componenti

  1. chromosome Source: RefGenome
  2. nucleus Source: RefGenome
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ2T9Y5.

Structurei

3D structure databases

ProteinModelPortaliQ2T9Y5.
SMRiQ2T9Y5. Positions 87-202.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000007653.
HOVERGENiHBG005515.
KOiK10776.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.30.1740.10. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
IPR001510. Znf_PARP.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
PF00645. zf-PARP. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
PS00347. PARP_ZN_FINGER_1. 1 hit.
PS50064. PARP_ZN_FINGER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2T9Y5-1 [UniParc]FASTAAdd to Basket

« Hide

MTLAFKILFP PTLRVLRKKE LCLFREHRRP DIRHFGRWSE TVFCGYHLLQ    50
RRKPVPSFQE SNLKLRATCL VYLPGSHVGL CSGPCEMAEQ RFCVDYAKRG 100
TAGCKKCKEK IVKGVCRIGK VVPNPFSESG GDMKEWYHIK CMFEKQERAP 150
ATTKKIEDLT ELEGWEELEE NEKEQISQHI ADLSSKATST PKKKAVVQAK 200
LTATGQVASP VKGASFVTNS NPRKFSGFSA KPNNSGEAHS SPTPKTPKTS 250
MSSSKCDPKH KDCLLREFRK LCAMVAENPS YNTKTQIIQD FLQKGSAGDG 300
FHGDVYLTVK LLLPGVIKSV YNLNDKQIVK LFSRIFNCNS DDMTRDLEQG 350
DVSETIRVFF EQSKSFPPAA KSLLTIQEVD EFLLRLSKLT KEDEQQQALQ 400
DIASRCTAND LKCIIRLIKH DLKMNSGAKH VLDALDPNAY EAFKASRNLQ 450
DVVERVLRNE QEVEKEPGQR RALSVQASLM TPVQPMLAEA CKSIEYAMKK 500
CPNGMFSEIK YDGERVQVHK KGDHFSYFSR SLKPVLPHKV AHFKDFIPRA 550
FPGGHSMILD SEVLLVDNRT GKPLPFGTLG VHKKAAFQDA NVCQFVFDCI 600
YFNDVSLMDR PLCERRKLLH DNMVEIPNRI MFSEMKQVTK ASDLVDMINR 650
VIQEGLEGLV LKDVKGTYEP GKRHWLKVKK DYLNEGAMAD TADLVVLGAF 700
YGQGSKGGMM SIFLMGCYDP SSQKWCTVTK CAGGHDDATL ARLQTELDMV 750
KISKDPSKIP NWLKINKIYY PDFIVPDPKK AAVWEITGAE FSKSEAHTAD 800
GISIRFPRCT RIRDDKDWKS ATTLPQLKEL YQLSKERAAF AITAGDEGSS 850
ATGGSSGENE GTSGPAVPHK APRASPKQPP TSAKKAGGKP GGCTSRGGNL 900
PAAEPSPVRA GVKRKAPDVT PCQAKRRPAS KRRGRRAVPT GRR 943
Length:943
Mass (Da):105,101
Last modified:January 24, 2006 - v1
Checksum:i05873FA748DA489F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC111207 mRNA. Translation: AAI11208.1.
RefSeqiNP_001033196.1. NM_001038107.2.
UniGeneiBt.25483.

Genome annotation databases

GeneIDi514719.
KEGGibta:514719.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC111207 mRNA. Translation: AAI11208.1 .
RefSeqi NP_001033196.1. NM_001038107.2.
UniGenei Bt.25483.

3D structure databases

ProteinModelPortali Q2T9Y5.
SMRi Q2T9Y5. Positions 87-202.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q2T9Y5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 514719.
KEGGi bta:514719.

Organism-specific databases

CTDi 3980.

Phylogenomic databases

HOGENOMi HOG000007653.
HOVERGENi HBG005515.
KOi K10776.

Miscellaneous databases

NextBioi 20871477.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.30.1740.10. 1 hit.
InterProi IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
IPR001510. Znf_PARP.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
PF00645. zf-PARP. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
PS00347. PARP_ZN_FINGER_1. 1 hit.
PS50064. PARP_ZN_FINGER_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Crossbred x AngusImported.
    Tissue: LiverImported.

Entry informationi

Entry nameiQ2T9Y5_BOVIN
AccessioniPrimary (citable) accession number: Q2T9Y5
Entry historyi
Integrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: April 16, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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