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Protein

F-box/WD repeat-containing protein 9

Gene

FBXW9

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.By similarity

Keywordsi

Biological processUbl conjugation pathway

Names & Taxonomyi

Protein namesi
Recommended name:
F-box/WD repeat-containing protein 9
Alternative name(s):
F-box and WD-40 domain-containing protein 9
Gene namesi
Name:FBXW9
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002494661 – 458F-box/WD repeat-containing protein 9Add BLAST458

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionineBy similarity1
Modified residuei18PhosphoserineBy similarity1
Modified residuei59PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiQ2T9T9.
PRIDEiQ2T9T9.

Interactioni

Subunit structurei

Interacts with SKP1 and CUL1.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000027872.

Structurei

3D structure databases

ProteinModelPortaliQ2T9T9.
SMRiQ2T9T9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini76 – 123F-boxPROSITE-ProRule annotationAdd BLAST48
Repeati171 – 210WD 1Add BLAST40
Repeati224 – 261WD 2Add BLAST38
Repeati264 – 301WD 3Add BLAST38
Repeati305 – 342WD 4Add BLAST38
Repeati344 – 381WD 5Add BLAST38
Repeati387 – 424WD 6Add BLAST38
Repeati427 – 458WD 7Add BLAST32

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

eggNOGiENOG410IQD3. Eukaryota.
ENOG4111G8F. LUCA.
HOGENOMiHOG000112556.
HOVERGENiHBG051598.
InParanoidiQ2T9T9.
KOiK10265.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiView protein in InterPro
IPR001810. F-box_dom.
IPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
PfamiView protein in Pfam
PF00400. WD40. 2 hits.
PRINTSiPR00320. GPROTEINBRPT.
SMARTiView protein in SMART
SM00256. FBOX. 1 hit.
SM00320. WD40. 6 hits.
SUPFAMiSSF50978. SSF50978. 1 hit.
SSF81383. SSF81383. 1 hit.
PROSITEiView protein in PROSITE
PS50181. FBOX. 1 hit.
PS00678. WD_REPEATS_1. 2 hits.
PS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2T9T9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELPPGPRDD PHAWDDDSDP ELEPDTDAQA EAYVARLLSP PKLGLAPPRA
60 70 80 90 100
PPLPAPTVSF GSLEPRAASK GPTVAVPGLL SLPPELLLEI CAYLDARLVL
110 120 130 140 150
HVLPRVCHAL RDLVRDRVTW RLRAQRRVRA PYPVVEEEDF DWPTACIELE
160 170 180 190 200
QHLSRWADDG RRAEYFCLAD GHFASIDSVL LLQGGTLCLS GSRDRNVNLW
210 220 230 240 250
DLQQLGVEPS RVLVKTLGTQ KNSTHKGWVW SLAALDHRVC SGSWDSTVKL
260 270 280 290 300
WDMAADGQQF GEIKGKAAVL CLSYRPDILV TGTYDKKVTV YDPRVGPALL
310 320 330 340 350
KSRRLHSSAV LALLADDRHI ISGSEDHTLV VFDRRANSVL QRLQLDSYLL
360 370 380 390 400
CMSYQEPQLW AGDNQGLLHV FANRSGCFQL VRSFDVGHRS QITGIKHSLG
410 420 430 440 450
ALYTTSTDKT IRVHVPTDPP RTICTRSHHN VLNGICAEGN LVVAASGGLS

LEVWRLQA
Length:458
Mass (Da):50,654
Last modified:January 24, 2006 - v1
Checksum:i8BAB059AE827994D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC111274 mRNA. Translation: AAI11275.1.
RefSeqiNP_001033240.1. NM_001038151.2.
UniGeneiBt.43176.

Genome annotation databases

GeneIDi532538.
KEGGibta:532538.

Similar proteinsi

Entry informationi

Entry nameiFBXW9_BOVIN
AccessioniPrimary (citable) accession number: Q2T9T9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2006
Last sequence update: January 24, 2006
Last modified: August 30, 2017
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome