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Protein

UPF0583 protein C15orf59

Gene

C15orf59

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0583 protein C15orf59
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 15

Organism-specific databases

HGNCiHGNC:33753. C15orf59.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162378260.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 293293UPF0583 protein C15orf59PRO_0000337045Add
BLAST

Proteomic databases

PaxDbiQ2T9L4.
PRIDEiQ2T9L4.

PTM databases

PhosphoSiteiQ2T9L4.

Expressioni

Gene expression databases

BgeeiQ2T9L4.
CleanExiHS_C15orf59.
ExpressionAtlasiQ2T9L4. baseline and differential.
GenevestigatoriQ2T9L4.

Organism-specific databases

HPAiHPA041563.

Interactioni

Protein-protein interaction databases

BioGridi132568. 1 interaction.
IntActiQ2T9L4. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliQ2T9L4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili30 – 6334Sequence AnalysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi207 – 2148Poly-Glu

Sequence similaritiesi

Belongs to the UPF0583 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG41340.
GeneTreeiENSGT00730000111309.
HOGENOMiHOG000072696.
HOVERGENiHBG107739.
InParanoidiQ2T9L4.
OMAiMNIRGTP.
OrthoDBiEOG7Q8CPJ.
PhylomeDBiQ2T9L4.
TreeFamiTF332382.

Family and domain databases

InterProiIPR027997. DUF4589.
[Graphical view]
PfamiPF15252. DUF4589. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2T9L4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIRGAPDLG QPSDDPSSGG ERERIRQRMK MVIGQLEGIL RELKEVAKEL
60 70 80 90 100
REVVSQIDKL TSDFDFELEP DDWTTATVSS TSSSDKAGMG GPFDLGHLDF
110 120 130 140 150
MTADILSDSW EFCSFLDVST PSDSVDGPES TRPGAGPDYR LMNGGTPIPN
160 170 180 190 200
GPRVETPDSS SEEAFGAGPT VKSQLPQRTP GTRERVRFSD KVLYHALCCD
210 220 230 240 250
DEEGDGEQEV EEEEVGLPPE PAHTEAHAGP HKPSPAPYKS RRSPLTSRHS
260 270 280 290
GSTLAPEQTR RVTRNSSTQT VSDKSTQTVL PYTATRQKAR GKN
Length:293
Mass (Da):31,928
Last modified:January 24, 2006 - v1
Checksum:iDC3E535979396B67
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC111368 mRNA. Translation: AAI11369.1.
CCDSiCCDS32289.1.
RefSeqiNP_001034703.1. NM_001039614.2.
XP_005254426.1. XM_005254369.2.
UniGeneiHs.213493.
Hs.40794.

Genome annotation databases

EnsembliENST00000379822; ENSP00000369150; ENSG00000205363.
ENST00000569673; ENSP00000457205; ENSG00000205363.
GeneIDi388135.
KEGGihsa:388135.
UCSCiuc002avy.3. human.

Polymorphism databases

DMDMi121941727.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC111368 mRNA. Translation: AAI11369.1.
CCDSiCCDS32289.1.
RefSeqiNP_001034703.1. NM_001039614.2.
XP_005254426.1. XM_005254369.2.
UniGeneiHs.213493.
Hs.40794.

3D structure databases

ProteinModelPortaliQ2T9L4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi132568. 1 interaction.
IntActiQ2T9L4. 1 interaction.

PTM databases

PhosphoSiteiQ2T9L4.

Polymorphism databases

DMDMi121941727.

Proteomic databases

PaxDbiQ2T9L4.
PRIDEiQ2T9L4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000379822; ENSP00000369150; ENSG00000205363.
ENST00000569673; ENSP00000457205; ENSG00000205363.
GeneIDi388135.
KEGGihsa:388135.
UCSCiuc002avy.3. human.

Organism-specific databases

CTDi388135.
GeneCardsiGC15M074032.
HGNCiHGNC:33753. C15orf59.
HPAiHPA041563.
neXtProtiNX_Q2T9L4.
PharmGKBiPA162378260.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG41340.
GeneTreeiENSGT00730000111309.
HOGENOMiHOG000072696.
HOVERGENiHBG107739.
InParanoidiQ2T9L4.
OMAiMNIRGTP.
OrthoDBiEOG7Q8CPJ.
PhylomeDBiQ2T9L4.
TreeFamiTF332382.

Miscellaneous databases

GenomeRNAii388135.
NextBioi101847.

Gene expression databases

BgeeiQ2T9L4.
CleanExiHS_C15orf59.
ExpressionAtlasiQ2T9L4. baseline and differential.
GenevestigatoriQ2T9L4.

Family and domain databases

InterProiIPR027997. DUF4589.
[Graphical view]
PfamiPF15252. DUF4589. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Embryonic stem cell.

Entry informationi

Entry nameiCO059_HUMAN
AccessioniPrimary (citable) accession number: Q2T9L4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: January 24, 2006
Last modified: March 4, 2015
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.