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Q2T9L4

- CO059_HUMAN

UniProt

Q2T9L4 - CO059_HUMAN

Protein

UPF0583 protein C15orf59

Gene

C15orf59

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (24 Jan 2006)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    UPF0583 protein C15orf59
    Gene namesi
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 15

    Organism-specific databases

    HGNCiHGNC:33753. C15orf59.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA162378260.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 293293UPF0583 protein C15orf59PRO_0000337045Add
    BLAST

    Proteomic databases

    PaxDbiQ2T9L4.
    PRIDEiQ2T9L4.

    PTM databases

    PhosphoSiteiQ2T9L4.

    Expressioni

    Gene expression databases

    ArrayExpressiQ2T9L4.
    BgeeiQ2T9L4.
    CleanExiHS_C15orf59.
    GenevestigatoriQ2T9L4.

    Organism-specific databases

    HPAiHPA041563.

    Interactioni

    Protein-protein interaction databases

    BioGridi132568. 1 interaction.
    IntActiQ2T9L4. 1 interaction.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2T9L4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili30 – 6334Sequence AnalysisAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi207 – 2148Poly-Glu

    Sequence similaritiesi

    Belongs to the UPF0583 family.Curated

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    eggNOGiNOG41340.
    HOGENOMiHOG000072696.
    HOVERGENiHBG107739.
    InParanoidiQ2T9L4.
    OMAiAPYKPRR.
    OrthoDBiEOG7Q8CPJ.
    PhylomeDBiQ2T9L4.
    TreeFamiTF332382.

    Family and domain databases

    InterProiIPR027997. DUF4589.
    [Graphical view]
    PfamiPF15252. DUF4589. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2T9L4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNIRGAPDLG QPSDDPSSGG ERERIRQRMK MVIGQLEGIL RELKEVAKEL    50
    REVVSQIDKL TSDFDFELEP DDWTTATVSS TSSSDKAGMG GPFDLGHLDF 100
    MTADILSDSW EFCSFLDVST PSDSVDGPES TRPGAGPDYR LMNGGTPIPN 150
    GPRVETPDSS SEEAFGAGPT VKSQLPQRTP GTRERVRFSD KVLYHALCCD 200
    DEEGDGEQEV EEEEVGLPPE PAHTEAHAGP HKPSPAPYKS RRSPLTSRHS 250
    GSTLAPEQTR RVTRNSSTQT VSDKSTQTVL PYTATRQKAR GKN 293
    Length:293
    Mass (Da):31,928
    Last modified:January 24, 2006 - v1
    Checksum:iDC3E535979396B67
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC111368 mRNA. Translation: AAI11369.1.
    CCDSiCCDS32289.1.
    RefSeqiNP_001034703.1. NM_001039614.1.
    XP_005254426.1. XM_005254369.2.
    UniGeneiHs.213493.
    Hs.40794.

    Genome annotation databases

    EnsembliENST00000379822; ENSP00000369150; ENSG00000205363.
    ENST00000569673; ENSP00000457205; ENSG00000205363.
    GeneIDi388135.
    KEGGihsa:388135.
    UCSCiuc002avy.3. human.

    Polymorphism databases

    DMDMi121941727.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC111368 mRNA. Translation: AAI11369.1 .
    CCDSi CCDS32289.1.
    RefSeqi NP_001034703.1. NM_001039614.1.
    XP_005254426.1. XM_005254369.2.
    UniGenei Hs.213493.
    Hs.40794.

    3D structure databases

    ProteinModelPortali Q2T9L4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 132568. 1 interaction.
    IntActi Q2T9L4. 1 interaction.

    PTM databases

    PhosphoSitei Q2T9L4.

    Polymorphism databases

    DMDMi 121941727.

    Proteomic databases

    PaxDbi Q2T9L4.
    PRIDEi Q2T9L4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000379822 ; ENSP00000369150 ; ENSG00000205363 .
    ENST00000569673 ; ENSP00000457205 ; ENSG00000205363 .
    GeneIDi 388135.
    KEGGi hsa:388135.
    UCSCi uc002avy.3. human.

    Organism-specific databases

    CTDi 388135.
    GeneCardsi GC15M074032.
    HGNCi HGNC:33753. C15orf59.
    HPAi HPA041563.
    neXtProti NX_Q2T9L4.
    PharmGKBi PA162378260.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG41340.
    HOGENOMi HOG000072696.
    HOVERGENi HBG107739.
    InParanoidi Q2T9L4.
    OMAi APYKPRR.
    OrthoDBi EOG7Q8CPJ.
    PhylomeDBi Q2T9L4.
    TreeFami TF332382.

    Miscellaneous databases

    GenomeRNAii 388135.
    NextBioi 101847.

    Gene expression databases

    ArrayExpressi Q2T9L4.
    Bgeei Q2T9L4.
    CleanExi HS_C15orf59.
    Genevestigatori Q2T9L4.

    Family and domain databases

    InterProi IPR027997. DUF4589.
    [Graphical view ]
    Pfami PF15252. DUF4589. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Embryonic stem cell.

    Entry informationi

    Entry nameiCO059_HUMAN
    AccessioniPrimary (citable) accession number: Q2T9L4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: January 24, 2006
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 15
      Human chromosome 15: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families
    3. Uncharacterized protein families (UPF)
      List of uncharacterized protein family (UPF) entries

    External Data

    Dasty 3