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Protein

RNA-binding protein 26

Gene

rbm26

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri327 – 35529C3H1-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Metal-binding, RNA-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
RNA-binding protein 26
Alternative name(s):
RNA-binding motif protein 26
Gene namesi
Name:rbm26
OrganismiXenopus laevis (African clawed frog)
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-960059. rbm26.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10591059RNA-binding protein 26PRO_0000273378Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ2T9I5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini581 – 65575RRM 1PROSITE-ProRule annotationAdd
BLAST
Domaini942 – 101170RRM 2PROSITE-ProRule annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili771 – 873103Sequence analysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi184 – 25067Arg-richAdd
BLAST
Compositional biasi365 – 477113Pro-richAdd
BLAST

Sequence similaritiesi

Contains 1 C3H1-type zinc finger.PROSITE-ProRule annotation
Contains 2 RRM (RNA recognition motif) domains.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri327 – 35529C3H1-typePROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Coiled coil, Repeat, Zinc-finger

Phylogenomic databases

HOVERGENiHBG057372.
KOiK13192.

Family and domain databases

Gene3Di1.20.1390.10. 1 hit.
3.30.70.330. 2 hits.
4.10.1000.10. 1 hit.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR002483. PWI_dom.
IPR000504. RRM_dom.
IPR000571. Znf_CCCH.
[Graphical view]
PfamiPF01480. PWI. 1 hit.
PF00076. RRM_1. 1 hit.
[Graphical view]
SMARTiSM00360. RRM. 2 hits.
SM00356. ZnF_C3H1. 1 hit.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 2 hits.
SSF90229. SSF90229. 1 hit.
PROSITEiPS50102. RRM. 2 hits.
PS50103. ZF_C3H1. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q2T9I5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MIIEDFEALK HWLSKTLEPI CDADPSALAK YVLALVKKDK SDRELNALCI
60 70 80 90 100
DQLDVFLQKE TQGFVDKLFD AINTKSYLPQ PDSTSTAVVK LDSFEHQEKE
110 120 130 140 150
IKKDEVNKEE EKEKKAPRRL NQSPQPSSTR HKDTRENRKR SNSDRESNSI
160 170 180 190 200
QNSFRSGLPE QKQDVDAAPP RLNSNKVQNA KNTRSRDDRK RDDRFRKREY
210 220 230 240 250
DRNVPRRDSY RDRYNRRRGR SRSYSRSRSR SWSKERQRDR DRSRSRTRSR
260 270 280 290 300
DKDSGKPKFD LDRPDPVDNS YASGSSVPHI GSAHFPVPTL SSTITVITPS
310 320 330 340 350
HHGNSSAENW PEFHEDQVDH SSYGRLQMQK KRCRDYDEKG FCMRGDMCPF
360 370 380 390 400
DHGSDPVVVE DVNLPGILPF PAPPPVLEGP PPPGLPPPPS LLTPPPVNLQ
410 420 430 440 450
PPPVPPPGPL PPSLPPVTGP PPPLPPLQPA GMDAPPNSAT SSVPTVVTTG
460 470 480 490 500
ILHPPPVPPS SLFPSAAAAA GPIPLFPETY EADGYNPEAP SMTTTSRPLY
510 520 530 540 550
RHRVHAQRPN LIGLTSGDMD LPTPREKNNM RIVVDSESRK RNLGSGDCVL
560 570 580 590 600
PSKKPWFDKS NFNNRMNPGF QKKPLFPNEN TKLELRRIPP ELNNISKLNE
610 620 630 640 650
HFSKFGTIVN LQVAYKGDPE GALIQFATHG EAKKAISSTE AVLNNRFIRM
660 670 680 690 700
YWHREGSSQQ LQTPGLPKVV HLTVPQQPNL SVMKQSIKER LGPVPANNSE
710 720 730 740 750
PSVAQNINTE TTQNIAKVPV KERLGYMSKT VSAATEKVFS TSTGLTKTVY
760 770 780 790 800
NPAALKAMQK SVLYPICNDN GDAQKKKQEA LKLQQDVRKK KQEILEKRIE
810 820 830 840 850
TQKILISKLE KNKNMKSEDK AEILKTLETL TNSITKLRDE LKAVSSTGNV
860 870 880 890 900
VKNNKSKAQM QKELLDTELD LYNKIQAGDD VTELRKKYTE LQLDAAKRGI
910 920 930 940 950
LSSGRGRGVH LRGRGVIRGR GRVLHGRGRG ASVHAVVDHR PRALKISGFT
960 970 980 990 1000
EGDREYLLPH FAHFGEIEDC QIDDSSLHAI ITFKTRAEAE AAAVHGAQFK
1010 1020 1030 1040 1050
GQDLKLAWNK PVPNASSTEV EDADQEEEEF HEDSIVDDSL LQDDDEEEED

DNESRSWRR
Length:1,059
Mass (Da):118,877
Last modified:January 23, 2007 - v2
Checksum:i37F4E6E09C5B3C1B
GO
Isoform 2 (identifier: Q2T9I5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     466-467: Missing.

Note: No experimental confirmation available.
Show »
Length:1,057
Mass (Da):118,735
Checksum:iAA931FC2AEA8CC0F
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti712 – 7121T → I in AAH43744 (Ref. 1) Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei466 – 4672Missing in isoform 2. 1 PublicationVSP_022536

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC043744 mRNA. Translation: AAH43744.1.
BC111508 mRNA. Translation: AAI11509.1.
RefSeqiNP_001079468.1. NM_001085999.1.
UniGeneiXl.24907.

Genome annotation databases

GeneIDi379155.
KEGGixla:379155.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC043744 mRNA. Translation: AAH43744.1.
BC111508 mRNA. Translation: AAI11509.1.
RefSeqiNP_001079468.1. NM_001085999.1.
UniGeneiXl.24907.

3D structure databases

ProteinModelPortaliQ2T9I5.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi379155.
KEGGixla:379155.

Organism-specific databases

CTDi64062.
XenbaseiXB-GENE-960059. rbm26.

Phylogenomic databases

HOVERGENiHBG057372.
KOiK13192.

Family and domain databases

Gene3Di1.20.1390.10. 1 hit.
3.30.70.330. 2 hits.
4.10.1000.10. 1 hit.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR002483. PWI_dom.
IPR000504. RRM_dom.
IPR000571. Znf_CCCH.
[Graphical view]
PfamiPF01480. PWI. 1 hit.
PF00076. RRM_1. 1 hit.
[Graphical view]
SMARTiSM00360. RRM. 2 hits.
SM00356. ZnF_C3H1. 1 hit.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 2 hits.
SSF90229. SSF90229. 1 hit.
PROSITEiPS50102. RRM. 2 hits.
PS50103. ZF_C3H1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Xenopus Gene Collection (XGC) project
    Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
    Tissue: Embryo and Oocyte.

Entry informationi

Entry nameiRBM26_XENLA
AccessioniPrimary (citable) accession number: Q2T9I5
Secondary accession number(s): Q7ZYK7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: January 23, 2007
Last modified: May 11, 2016
This is version 56 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.