Q2T9H3 (Q2T9H3_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
SLC5A7 protein EMBL AAI11525.1

Gene names

Name:

SLC5A7 EMBL AAI11525.1

Organism

Homo sapiens (Human) EMBL AAI11525.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	333 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Membrane; Multi-pass membrane protein By similarity RuleBase RU003736.
Sequence similarities	Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. [View classification] RuleBase RU003736

Ontologies

Keywords
Biological process	Transport RuleBase RU003736
Cellular component	Membrane
Domain	Transmembrane RuleBase RU003736
Gene Ontology (GO)
Biological_process	acetylcholine biosynthetic process Inferred from electronic annotation. Source: Compara neuromuscular synaptic transmission Inferred from electronic annotation. Source: Compara synaptic transmission, cholinergic Inferred from electronic annotation. Source: Compara
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW neuronal cell body Inferred from electronic annotation. Source: Compara plasma membrane Inferred from electronic annotation. Source: Compara
Molecular_function	choline binding Inferred from electronic annotation. Source: Compara choline transmembrane transporter activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2T9H3 [UniParc]. Last modified January 24, 2006. Version 1. Checksum: CFD53B586CABA372	FASTA	333	36,585
	10 20 30 40 50 60 MLGGIPWQAY FQRVLSSSSA TYAQVLSFLA AFGCLVMAIP AILIGAIGAS TDWNQTAYGL 70 80 90 100 110 120 PDPKTTEEAD MILPIVLQYL CPVYISFFGL GAVSAAVMSS ADSSILSASS MFARNIYQLS 130 140 150 160 170 180 FRQNASDKEI VWVMRITVFV FGASATAMAL LTKTVYGLWY LSSDLVYIVI FPQLLCVLFV 190 200 210 220 230 240 KGTNTYGAVA GYVSGLFLRI TGGEPYLYLQ PLIFYPGYYP DDNGIYNQKF PFKTLAMVTS 250 260 270 280 290 300 FLTNICISYL AKYLFESGTL PPKLDVFDAV VARHSEENMD KTILVKNENI KLDELALVKP 310 320 330 RQSMTLSSTF TNKEAFLDVD SSPEGSGTED NLQ

References

[1]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: PCR rescued clones EMBL AAI11525.1.

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC111524 mRNA. Translation: AAI11525.1.
IPI	IPI01009671.
UniGene	Hs.287758.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q2T9H3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG054160.
Gene expression databases
ArrayExpress	Q2T9H3.
Bgee	Q2T9H3.
Family and domain databases
InterPro	IPR001734. Na/solute_symporter. [Graphical view]
PANTHER	PTHR11819. PTHR11819. 1 hit.
Pfam	PF00474. SSF. 1 hit. [Graphical view]
PROSITE	PS50283. NA_SOLUT_SYMP_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q2T9H3_HUMAN

Accession

Primary (citable) accession number: Q2T9H3

Entry history

Integrated into UniProtKB/TrEMBL:	January 24, 2006
Last sequence update:	January 24, 2006
Last modified:	October 3, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.