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Protein

Sex-determining region Y protein

Gene

Sry

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi5 – 73HMG boxPROSITE-ProRule annotationAdd BLAST69

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywordsi

Molecular functionActivatorSAAS annotation, Calmodulin-bindingSAAS annotation, DNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processDifferentiation, Sexual differentiationSAAS annotation, Transcription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Sex-determining region Y proteinSAAS annotation
Gene namesi
Name:SryImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:98660. Sry.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiQ2T9H0.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000088717.

Structurei

3D structure databases

ProteinModelPortaliQ2T9H0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 73HMG box DNA-bindingInterPro annotationAdd BLAST69

Sequence similaritiesi

Belongs to the SRY family.SAAS annotation
Contains 1 HMG box DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0527. Eukaryota.
ENOG410XT0K. LUCA.
HOVERGENiHBG008712.

Family and domain databases

Gene3Di1.10.30.10. 1 hit.
InterProiIPR009071. HMG_box_dom.
IPR017253. SRY.
[Graphical view]
PANTHERiPTHR10270:SF199. PTHR10270:SF199. 1 hit.
PfamiPF00505. HMG_box. 1 hit.
[Graphical view]
SMARTiSM00398. HMG. 1 hit.
[Graphical view]
SUPFAMiSSF47095. SSF47095. 1 hit.
PROSITEiPS50118. HMG_BOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2T9H0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGHVKRPMN AFMVWSRGER HKLAQQNPSM QNTEISKQLG CRWKSLTEAE
60 70 80 90 100
KRPFFQEAQR LKILHREKYP NYKYQPHRRA KVSQRSGILQ PAVASTKLYN
110 120 130 140 150
LLQWDRNPHA ITYRQDWSRA AHLYSKNQQS FYWQPVDIPT GHLQQQQQQQ
160 170 180 190 200
QQQQFHNHHQ QQQQFYDHHQ QQQQQQQQQQ QFHDHHQQKQ QFHDHHQQQQ
210 220 230 240 250
QFHDHHHHHQ EQQFHDHHQQ QQQFHDHQQQ QQQQQQQQFH DHHQQKQQFH
260 270 280 290 300
DHHHHQQQQQ FHDHQQQQQQ FHDHQQQQHQ FHDHPQQKQQ FHDHPQQQQQ
310 320 330 340 350
FHDHHHQQQQ KQQFHDHHQQ KQQFHDHHQQ KQQQQQQQQQ FHDQQLTYLL
360 370
TADITGEHTP YQEHLSTALW LAVS
Length:374
Mass (Da):46,737
Last modified:January 24, 2006 - v1
Checksum:iCCE24B5529A29A95
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC111528 mRNA. Translation: AAI11529.1.
UniGeneiMm.377114.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC111528 mRNA. Translation: AAI11529.1.
UniGeneiMm.377114.

3D structure databases

ProteinModelPortaliQ2T9H0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000088717.

Proteomic databases

PaxDbiQ2T9H0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:98660. Sry.

Phylogenomic databases

eggNOGiKOG0527. Eukaryota.
ENOG410XT0K. LUCA.
HOVERGENiHBG008712.

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

Gene3Di1.10.30.10. 1 hit.
InterProiIPR009071. HMG_box_dom.
IPR017253. SRY.
[Graphical view]
PANTHERiPTHR10270:SF199. PTHR10270:SF199. 1 hit.
PfamiPF00505. HMG_box. 1 hit.
[Graphical view]
SMARTiSM00398. HMG. 1 hit.
[Graphical view]
SUPFAMiSSF47095. SSF47095. 1 hit.
PROSITEiPS50118. HMG_BOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ2T9H0_MOUSE
AccessioniPrimary (citable) accession number: Q2T9H0
Entry historyiIntegrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: January 18, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.