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Q2T6R3 (GLGB_BURTA) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
1,4-alpha-glucan branching enzyme GlgB

EC=2.4.1.18
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase
Alpha-(1->4)-glucan branching enzyme
Glycogen branching enzyme
Short name=BE
Gene names
Name:glgB
Ordered Locus Names:BTH_II0939
OrganismBurkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301) [Complete proteome] [HAMAP]
Taxonomic identifier271848 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group

Protein attributes

Sequence length834 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity. HAMAP-Rule MF_00685

Catalytic activity

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain. HAMAP-Rule MF_00685

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00685

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00685

Sequence similarities

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 8348341,4-alpha-glucan branching enzyme GlgB HAMAP-Rule MF_00685
PRO_0000260640

Sites

Active site5111Nucleophile By similarity
Active site5651Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2T6R3 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: 59BCF5695BFA9C18

FASTA83492,904
        10         20         30         40         50         60 
MTGIGARTAW RNAVGRRPRN ARRVSRIAYR VSRVACRVSR IAYRVSRIAY RVSRVAWRNV 

        70         80         90        100        110        120 
APAARRAHRP FPAVIHIASG IPLPTEPLPA PPVVVDRPAS PDDAALIAPD DLARLLRGEH 

       130        140        150        160        170        180 
DDPFAVLGIH AESSARDVVV RCLLPGAARV ELIDAASART LATLSPVGSG ELHAIRLPAP 

       190        200        210        220        230        240 
GPLRYRLRAH YADTVRDLDD PYACTPWLGS LDCHLLARGE HRDAYRRLGA HPCVHDGLEG 

       250        260        270        280        290        300 
TAFALWAPNA SCVSVVGSFN GWDARVHAMR KRIECGVWEL FVPGVGCGAL YKFALRTRDG 

       310        320        330        340        350        360 
DRLLKADPYA RRTEAPPRTA SRICAPSAFG WRDDAWMRER AAAQSAHAPI AIYEVHLDSW 

       370        380        390        400        410        420 
RRHPDGRAYS YDELADALIP YVAALGFTHV ELLPIAEYPF AGSWGYQPVS LFAPSARWGE 

       430        440        450        460        470        480 
PDALRRFVER CHLAGLGVLL DWVPAHFPQD AHGLARFDGT HLYEHEDRRV GLHRGWNTLV 

       490        500        510        520        530        540 
YNLGRHEVAN FLIANALYWL REFHFDGLRV DAVASMLYLD YDRDDGQWLP NVHGGRENLE 

       550        560        570        580        590        600 
AVAFLRRLNE TVHADAPQGA ITIAEESTAW PMVSAPVAAG GLGFDFKWNM GWMNDTLSFM 

       610        620        630        640        650        660 
RVDPIHRRFH LDRLTFGLLY AWSEQFVLAL SHDEVVHAKG SLLAKMPGDA WQRHANLRLY 

       670        680        690        700        710        720 
LAFQYAHPGK KLLFMGSEFG QEREWNHDRE LDWARLADPA SAGVRRLVGD LNRLYRRRGC 

       730        740        750        760        770        780 
LHRRDADSRG FRWIDCADSH QTVIAWRRIG DAPDDFVVVV CNFTPQPRTG YRIGVPAAGF 

       790        800        810        820        830 
YRELLNSDAA DYGGSGLGNL GGVSSEPVPM HGEPHSLSLL LPPLAALVFA APGH 

« Hide

References

[1]"Bacterial genome adaptation to niches: divergence of the potential virulence genes in three Burkholderia species of different survival strategies."
Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C., DeShazer D.
BMC Genomics 6:174-174(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: E264 / ATCC 700388 / DSM 13276 / CIP 106301.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000085 Genomic DNA. Translation: ABC35639.1.
RefSeqYP_439136.1. NC_007650.1.

3D structure databases

ProteinModelPortalQ2T6R3.
SMRQ2T6R3. Positions 221-832.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING271848.BTH_II0939.

Protein family/group databases

CAZyCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABC35639; ABC35639; BTH_II0939.
GeneID3845029.
KEGGbte:BTH_II0939.
PATRIC19299451. VBIBurTha36512_1055.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0296.
HOGENOMHOG000283037.
KOK00700.
OMAAKLLFMG.
OrthoDBEOG6JX7GT.

Enzyme and pathway databases

BioCycBTHA271848:GJMY-4282-MONOMER.
UniPathwayUPA00164.

Family and domain databases

Gene3D2.60.40.10. 2 hits.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPMF_00685. GlgB.
InterProIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERPTHR10357. PTHR10357. 1 hit.
PfamPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFPIRSF000463. GlgB. 1 hit.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 1 hit.
TIGRFAMsTIGR01515. branching_enzym. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGB_BURTA
AccessionPrimary (citable) accession number: Q2T6R3
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: January 24, 2006
Last modified: June 11, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries