Reviewed,
UniProtKB/Swiss-Prot Q2T6D0 (BETA_BURTA)
Last modified
February 9, 2010.
Version 35.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Choline dehydrogenase Short name=CHD Short name=CDH EC=1.1.99.1 | ||||
| Gene names |
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| Organism | Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 271848 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group |
Protein attributes
| Sequence length | 565 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine By similarity. HAMAP MF_00750 |
| Catalytic activity | Choline + acceptor = betaine aldehyde + reduced acceptor. HAMAP MF_00750 |
| Cofactor | FAD By similarity. HAMAP MF_00750 |
| Pathway | Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1. HAMAP MF_00750 |
| Sequence similarities | Belongs to the GMC oxidoreductase family. |
Ontologies
| Keywords | |
|---|---|
| Ligand | FAD Flavoprotein |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | glycine betaine biosynthetic process from choline Inferred from electronic annotation. Source: HAMAP oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | FAD binding Inferred from electronic annotation. Source: InterPro choline dehydrogenase activityInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 565 | 565 | Choline dehydrogenase HAMAP MF_00750 | PRO_0000258922 | |||||
Regions | |||||||||
| Nucleotide binding | 7 – 36 | 30 | FAD Probable | ||||||
Sites | |||||||||
| Active site | 474 | 1 | By similarity | ||||||
Sequences
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References
| [1] | Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A., Lathigra R., White O., Ketchum K.A., Palmer N., Dodson R., Hickey E.K., Gwinn M.L., Dougherty B., Fleischmann R.D., Richardson D.L., Peterson J.D., Kerlavage A.R., Quackenbush J. Venter J.C.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000085 Genomic DNA. Translation: ABC35233.1. |
| RefSeq | YP_439269.1. |
3D structure databases | |
| SMR | Q2T6D0. Positions 1-532. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q2T6D0. |
Genome annotation databases | |
| GeneID | 3846715. |
| GenomeReviews | Gene locus BTH_II1072 in contig CP000085_GR. |
| KEGG | bte:BTH_II1072. |
| TIGR | BTH_II1072. |
Phylogenomic databases | |
| eggNOG | COG2303. |
| HOGENOM | HBG734713. |
| OMA | RTVTPHG. |
Enzyme and pathway databases | |
| BioCyc | BTHA271848:BTH_II1072-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00750. Choline_dehydrogen. [Tree] |
| InterPro | IPR011533. Choline_dehydrogenase. IPR012132. GMC_OxRdtase. IPR000172. GMC_OxRdtase_N. IPR007867. GMC_OxRtase_C. [Graphical view] |
| Pfam | PF05199. GMC_oxred_C. 1 hit. PF00732. GMC_oxred_N. 1 hit. [Graphical view] |
| PIRSF | PIRSF000137. Alcohol_oxidase. 1 hit. |
| TIGRFAMs | TIGR01810. betA. 1 hit. |
| PROSITE | PS00623. GMC_OXRED_1. 1 hit. PS00624. GMC_OXRED_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | BETA_BURTA | ||||||||
| Accession | Primary (citable) accession number: Q2T6D0 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


