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Q2T4J0 (Q2T4J0_BURTA) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine racemase 2 HAMAP MF_01201
EC=5.1.1.1 HAMAP MF_01201
Gene names
Name:alr-2 EMBL ABC36031.1
Synonyms:alr2 HAMAP MF_01201
Ordered Locus Names:BTH_II1715
OrganismBurkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301) [Complete proteome] [HAMAP] EMBL ABC36031.1
Taxonomic identifier271848 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length386 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the D-alanine required for cell wall biosynthesis By similarity. HAMAP MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP MF_01201 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP MF_01201 SAAS SAAS009006

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP MF_01201

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site471Proton acceptor; specific for D-alanine By similarity HAMAP MF_01201
Active site2641Proton acceptor; specific for L-alanine By similarity HAMAP MF_01201

Amino acid modifications

Modified residue471N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01201

Sequences

Sequence LengthMass (Da)Tools
Q2T4J0 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: 3623C85050828C58

FASTA38641,884
        10         20         30         40         50         60 
MRARRLDFAE RFMPRPIVAR IHPDAIAHNL AIVRQKAPNS RVWSVVKANA YGHGIERVYP 

        70         80         90        100        110        120 
ALADADGIAL LDLDEAVRVR ALGWTKPVLL LEGIFDAADI EIADRHRLTV AVHGDEQLKL 

       130        140        150        160        170        180 
LTSAKTTRPI DIQLKMNSGM NRLGYRPSAF RDAWERAAAA PSIGRIALMM HFANADDGEI 

       190        200        210        220        230        240 
DWQMSVFDAA TDGLPGERTL SNSAAVLWHP RAHRDWVRPG TILYGASPTG ATRHVADVPL 

       250        260        270        280        290        300 
RAAMTLTSRI IGVQTLSPGE TVGYGRRFAA EREMRIGVVA CGYADGYPRH APSGTPIAVD 

       310        320        330        340        350        360 
GVLTRVVGRV SMDMLTVDLT PCPHAGVGST VELWGKQVRV DDVAEAAGTI GYELMCALAR 

       370        380 
RVPVVVDPHP AAETHAQPAR TGSYGR

« Hide

References

[1]"Bacterial genome adaptation to niches: divergence of the potential virulence genes in three Burkholderia species of different survival strategies."
Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C., DeShazer D.
BMC Genomics 6:174-174(2005) [PubMed: 16336651] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: E264 / ATCC 700388 / DSM 13276 / CIP 106301.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000085 Genomic DNA. Translation: ABC36031.1.
RefSeqYP_439909.2. NC_007650.1.

3D structure databases

ProteinModelPortalQ2T4J0.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2T4J0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3845694.
GenomeReviewsGene locus BTH_II1715 in contig CP000085_GR.
KEGGbte:BTH_II1715.
PATRIC19301150. VBIBurTha36512_1903.
TIGRBTH_II1715.

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHBG712172.
OMASVELWGD.
ProtClustDBPRK13340.

Family and domain databases

HAMAPMF_01201. Ala_racemase.
[Tree]
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
Gene3DG3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 1 hit.
KOK01775.
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. Alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ2T4J0_BURTA
AccessionPrimary (citable) accession number: Q2T4J0
Entry history
Integrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info