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Q2T2B2 (Q2T2B2_BURTA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide deformylase 1 HAMAP MF_00163
Short name=PDF 1 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163
Alternative name(s):
Polypeptide deformylase 1 HAMAP MF_00163
Gene names
Name:def-1 EMBL ABC36838.1
Synonyms:def1 HAMAP MF_00163
Ordered Locus Names:BTH_I0128
OrganismBurkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301) [Complete proteome] [HAMAP]
Taxonomic identifier271848 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length179 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163

Catalytic activity

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181

Cofactor

Binds 1 Fe2+ ion By similarity. HAMAP MF_00163

Sequence similarities

Belongs to the polypeptide deformylase family. HAMAP MF_00163 RuleBase RU003335

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1471 By similarity HAMAP MF_00163
Metal binding1041Iron By similarity HAMAP MF_00163
Metal binding1461Iron By similarity HAMAP MF_00163
Metal binding1501Iron By similarity HAMAP MF_00163

Sequences

Sequence LengthMass (Da)Tools
Q2T2B2 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: 9A9016B7636E462F

FASTA17920,472
        10         20         30         40         50         60 
MRAGRSSLNT EIMALLNILH YPDKRLHKVA KPVDKVDDRI RRLVADMAET MYAAPGIGLA 

        70         80         90        100        110        120 
ATQVDVHERV IVIDVSEDKN ELRVFINPEI VWTSDGKQVY EEGCLSVPGV YDEVERPDRV 

       130        140        150        160        170 
RVRALDEQGE PFELDCEGLL AVCIQHEMDH LMGRVFVQYL SPLKQTRIKT KMKKLERAM

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References

[1]"Bacterial genome adaptation to niches: divergence of the potential virulence genes in three Burkholderia species of different survival strategies."
Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C., DeShazer D.
BMC Genomics 6:174-174(2005) [PubMed: 16336651] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: E264 / ATCC 700388 / DSM 13276 / CIP 106301.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000086 Genomic DNA. Translation: ABC36838.1.
RefSeqYP_440687.3. NC_007651.1.

3D structure databases

ProteinModelPortalQ2T2B2.
SMRQ2T2B2. Positions 13-177.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2T2B2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3848354.
GenomeReviewsGene locus BTH_I0128 in contig CP000086_GR.
KEGGbte:BTH_I0128.
PATRIC19302904. VBIBurTha36512_2772.
TIGRBTH_I0128.

Phylogenomic databases

eggNOGCOG0242.
HOGENOMHBG665227.
OMAQKIVDDM.
ProtClustDBPRK00150.

Family and domain databases

HAMAPMF_00163. Pep_deformylase.
[Tree]
InterProIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
Gene3DG3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KOK01462.
PANTHERPTHR10458. Fmet_deformylase. 1 hit.
PfamPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFPIRSF004749. Pep_def. 1 hit.
PRINTSPR01576. PDEFORMYLASE.
SUPFAMSSF56420. Fmet_deformylase. 1 hit.
TIGRFAMsTIGR00079. Pept_deformyl. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ2T2B2_BURTA
AccessionPrimary (citable) accession number: Q2T2B2
Entry history
Integrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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