ID   DAPF_BURTA              Reviewed;         289 AA.
AC   Q2T269;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   16-JUN-2009, entry version 24.
DE   RecName: Full=Diaminopimelate epimerase;
DE            Short=DAP epimerase;
DE            EC=5.1.1.7;
GN   Name=dapF; OrderedLocusNames=BTH_I0172;
OS   Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 /
OS   CIP 106301).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=271848;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A.,
RA   Lathigra R., White O., Ketchum K.A., Palmer N., Dodson R.,
RA   Hickey E.K., Gwinn M.L., Dougherty B., Fleischmann R.D.,
RA   Richardson D.L., Peterson J.D., Kerlavage A.R., Quackenbush J.,
RA   Salzberg S.L., Hanson M., van-Vugt R., Adams M.D., Gocayne J.D.,
RA   Weidman J., Utterback T.R., Watthey L., McDonald L.A., Artiach P.,
RA   Bowman C., Garland S., Fujii C., Cotton M.D., Horst K., Tomb J.-F.,
RA   Roberts K., Hatch B., Smith H.O., Venter J.C.;
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: LL-2,6-diaminoheptanedioate = meso-
CC       diaminoheptanedioate.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-lysine biosynthesis via DAP
CC       pathway; DL-diaminopimelate from LL-diaminopimelate: step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the diaminopimelate epimerase family.
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DR   EMBL; CP000086; ABC37078.1; -; Genomic_DNA.
DR   RefSeq; YP_440730.1; -.
DR   GeneID; 3846850; -.
DR   GenomeReviews; CP000086_GR; BTH_I0172.
DR   KEGG; bte:BTH_I0172; -.
DR   TIGR; BTH_I0172; -.
DR   HOGENOM; Q2T269; -.
DR   OMA; Q2T269; PHAVLRV.
DR   BioCyc; BTHA271848:BTH_I0172-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008837; F:diaminopimelate epimerase activity; IEA:HAMAP.
DR   GO; GO:0009089; P:lysine biosynthetic process via diaminopime...; IEA:HAMAP.
DR   HAMAP; MF_00197; -; 1.
DR   InterPro; IPR001653; DAP_epimerase.
DR   InterPro; IPR018510; DAP_epimerase_CS.
DR   Pfam; PF01678; DAP_epimerase; 2.
DR   TIGRFAMs; TIGR00652; DapF; 1.
DR   PROSITE; PS01326; DAP_EPIMERASE; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis; Complete proteome; Cytoplasm; Isomerase;
KW   Lysine biosynthesis.
FT   CHAIN         1    289       Diaminopimelate epimerase.
FT                                /FTId=PRO_1000011861.
FT   ACT_SITE     76     76       By similarity.
FT   ACT_SITE    227    227       By similarity.
SQ   SEQUENCE   289 AA;  30969 MW;  6640BE1ADB35EACC CRC64;
     MKLSFTKMHG AGNDFVVLDG YSRALPPLTD ALVRALADRH FGIGADQLLL VEKPTVDGAD
     FKYRIFNCDG GEVEHCGNGA RCFVKFVRDH GLTDKASVRV EVKHGVITLT MQDNGEVVVD
     MGAPVFEPAR VPFDTSGLDG RREGADTLWP LPVNGATRWI SVVSMGNPHA VQIVDDAEAF
     PVLADGPAIE RDPRFPQRVN AGFMQIVSRH EVKLRVYERG AGETLACGTG ACAAVAAGIR
     RGQLDSPVTV HTHGGTLTIS WDGARDERAP LMMAGPATTV FEGVIDLPA
//