ID   BIOD_BURTA              Reviewed;         240 AA.
AC   Q2T1Q3;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   16-JUN-2009, entry version 20.
DE   RecName: Full=Dethiobiotin synthetase;
DE            EC=6.3.3.3;
DE   AltName: Full=Dethiobiotin synthase;
DE   AltName: Full=DTB synthetase;
DE            Short=DTBS;
GN   Name=bioD; OrderedLocusNames=BTH_I0338;
OS   Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 /
OS   CIP 106301).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=271848;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A.,
RA   Lathigra R., White O., Ketchum K.A., Palmer N., Dodson R.,
RA   Hickey E.K., Gwinn M.L., Dougherty B., Fleischmann R.D.,
RA   Richardson D.L., Peterson J.D., Kerlavage A.R., Quackenbush J.,
RA   Salzberg S.L., Hanson M., van-Vugt R., Adams M.D., Gocayne J.D.,
RA   Weidman J., Utterback T.R., Watthey L., McDonald L.A., Artiach P.,
RA   Bowman C., Garland S., Fujii C., Cotton M.D., Horst K., Tomb J.-F.,
RA   Roberts K., Hatch B., Smith H.O., Venter J.C.;
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: ATP + 7,8-diaminononanoate + CO(2) = ADP +
CC       phosphate + dethiobiotin.
CC   -!- COFACTOR: Magnesium (By similarity).
CC   -!- PATHWAY: Cofactor biosynthesis; biotin biosynthesis; biotin from
CC       6-carboxyhexanoyl-CoA: step 3/4.
CC   -!- SIMILARITY: Belongs to the dethiobiotin synthetase family.
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DR   EMBL; CP000086; ABC39482.1; -; Genomic_DNA.
DR   RefSeq; YP_440896.1; -.
DR   GeneID; 3848467; -.
DR   GenomeReviews; CP000086_GR; BTH_I0338.
DR   KEGG; bte:BTH_I0338; -.
DR   TIGR; BTH_I0338; -.
DR   HOGENOM; Q2T1Q3; -.
DR   OMA; Q2T1Q3; HRRACER.
DR   BioCyc; BTHA271848:BTH_I0338-MON; -.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0004141; F:dethiobiotin synthase activity; IEA:HAMAP.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:HAMAP.
DR   GO; GO:0009102; P:biotin biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00336; -; 1.
DR   InterPro; IPR004472; BioD_synth.
DR   PIRSF; PIRSF006755; DTB_synth; 1.
DR   TIGRFAMs; TIGR00347; bioD; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Biotin biosynthesis; Complete proteome; Ligase;
KW   Magnesium; Nucleotide-binding.
FT   CHAIN         1    240       Dethiobiotin synthetase.
FT                                /FTId=PRO_0000302494.
FT   NP_BIND      11     19       ATP (By similarity).
SQ   SEQUENCE   240 AA;  24955 MW;  71BA9D43748EA278 CRC64;
     MSAPLSLFVT GTDTEIGKTF VSTALLHGFA RAGLRAAAMK PIAAGAYQRD GVWRNEDADQ
     LDAAANVALP ATIRTPFLLK AAAAPHIAAA REGVALDIDT IVGAHRRACE RADVVVVEGV
     GGFRVPLAGT RDTADLAVAL GLPVVLVVGV RLGCISHALL TADAIAARGL AIAGWVANRV
     DAAMRFADDN VDTLRAWLER EHGAPLLGDI AHMSPPSPEA ASRSLDVNRL LGALRETAPR
//