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Q2T1N6 (SYR_BURTA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:BTH_I0355
OrganismBurkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301) [Complete proteome] [HAMAP]
Taxonomic identifier271848 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group

Protein attributes

Sequence length594 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 594594Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000242000

Regions

Motif139 – 14911"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q2T1N6 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: F68CAC6E57BFBF19

FASTA59464,580
        10         20         30         40         50         60 
MLPAQKHTLE TLLENSVKQV VQASKGDADA AFVLPAIALE RPKVAAHGDV ACNVALQLAK 

        70         80         90        100        110        120 
PLGANPRQLA ERIVAALTAQ PAAAGLVDAA EIAGPGFINL RLTPASKQAV IGAVFAQGRA 

       130        140        150        160        170        180 
FGASEREHGK RVLLEFVSAN PTGPLHVGHG RQAALGDALA NVLASQGYAV HREFYYNDAG 

       190        200        210        220        230        240 
VQIGNLAIST QARARGLKPG DAGWPEAAYN GEYIADIARD YLNGETVAAS DGEPVTGKRD 

       250        260        270        280        290        300 
ADDLEAIRKF AVAYLRREQD MDLKAFGVKF DQYYLESSLY TEGRVEKTVD ALIAAGMTYE 

       310        320        330        340        350        360 
QEGALWLRTT DEGDDKDRVM RKTDGTYTYF VPDVAYHVTK WERGFTKVIN IQGSDHHGTI 

       370        380        390        400        410        420 
ARVRAGLQGL HIGIPKGYPD YVLHKMVTVM RDGQEVKISK RAGSYVTVRD LIEWSGGATP 

       430        440        450        460        470        480 
GSEVSPELLD EATITRGRDA VRFFLISRKA DTEFVFDIDL ALKQNDENPV YYVQYAHARI 

       490        500        510        520        530        540 
CSVLNEWKSR YGATDALLPG ADLSPLDSKQ AMALMQKLAE YPDVLAHAAN ELAPHAVAFY 

       550        560        570        580        590 
LRELASEFHS FYNAERVLVD EEAPRTARIA LLAATRQVLE NGLAMLGVSA PSKM 

« Hide

References

[1]"Bacterial genome adaptation to niches: divergence of the potential virulence genes in three Burkholderia species of different survival strategies."
Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C., DeShazer D.
BMC Genomics 6:174-174(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: E264 / ATCC 700388 / DSM 13276 / CIP 106301.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000086 Genomic DNA. Translation: ABC39196.1.
RefSeqYP_440913.1. NC_007651.1.

3D structure databases

ProteinModelPortalQ2T1N6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING271848.BTH_I0355.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABC39196; ABC39196; BTH_I0355.
GeneID3849444.
KEGGbte:BTH_I0355.
PATRIC19303406. VBIBurTha36512_3022.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMANPNGPLH.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycBTHA271848:GJMY-355-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_BURTA
AccessionPrimary (citable) accession number: Q2T1N6
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: January 24, 2006
Last modified: April 16, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries