ID   Q2T0X4_BURTA            Unreviewed;       583 AA.
AC   Q2T0X4;
DT   24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT   24-JAN-2006, sequence version 1.
DT   27-MAR-2024, entry version 109.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:ABC36613.1};
GN   OrderedLocusNames=BTH_I0618 {ECO:0000313|EMBL:ABC36613.1};
OS   Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CCUG 48851 /
OS   CIP 106301 / E264).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=271848 {ECO:0000313|EMBL:ABC36613.1, ECO:0000313|Proteomes:UP000001930};
RN   [1] {ECO:0000313|EMBL:ABC36613.1, ECO:0000313|Proteomes:UP000001930}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700388 / DSM 13276 / CIP 106301 / E264
RC   {ECO:0000313|Proteomes:UP000001930};
RX   PubMed=16336651; DOI=10.1186/1471-2164-6-174;
RA   Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C.,
RA   DeShazer D.;
RT   "Bacterial genome adaptation to niches: divergence of the potential
RT   virulence genes in three Burkholderia species of different survival
RT   strategies.";
RL   BMC Genomics 6:174-174(2005).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000086; ABC36613.1; -; Genomic_DNA.
DR   RefSeq; WP_009892841.1; NZ_CP008785.1.
DR   AlphaFoldDB; Q2T0X4; -.
DR   KEGG; bte:BTH_I0618; -.
DR   HOGENOM; CLU_000445_107_26_4; -.
DR   Proteomes; UP000001930; Chromosome I.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd11386; MCP_signal; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013655; PAS_fold_3.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR43531:SF7; AEROTAXIS RECEPTOR; 1.
DR   PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   SMART; SM00283; MA; 1.
DR   SMART; SM00086; PAC; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        171..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          25..60
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          214..266
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          271..500
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   REGION          520..583
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        520..541
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        560..583
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   583 AA;  62431 MW;  A16CCCC6AE7E889F CRC64;
     MRANLPVTQR EFDFPDDATL MSTTDPQSYV TYANAAFIQV SGFERDEIIG EPHNFVRHPD
     MPAEAFADMW ATLKSGRSWT AVIKNRRKNG DHYWVRANAT PVIRNGQLVG YMSVRTKPSR
     EEIAQADALY RDLREHRARG RKFHQGLIVR TGLLGWMSLP QTISARWRVR AALLTLLAGS
     AWTAFLCGLH GVMLDGFAAT ETVLLLLAEF WLAAQITGPL QRVLKQSLAV AAGQAGDNVH
     LNRVDEIGMI MRAVNQAGLN LRSLVDDVSE QLSGLQSASG RITAGNDDLS GRSEQAAASL
     EETAASMEQM TATVRNNADT ATQASQLAGS TSEAAEKGDA VVGKVVATMG EISASSRKIS
     EIIGVIDSIA FQTNILALNA AVEAARAGEQ GRGFAVVAAE VRTLAQRSAN AAKEIAALIH
     DSAQKTAAGS ALVDQAGEAM NDIRSQVARV AGLIGEISSA TREQSDGIGQ VNVAVTQLDK
     MTQQNAALVQ ESATTADELK RRTQRLVDAV AVFRLNGRAH ARRDDARAPR AAPEHAMRER
     ASVARNQPAM RAAPAPSPAL ASASTANAPA RTTAHADMDW QTF
//