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Q2T0S5

- Q2T0S5_BURTA

UniProt

Q2T0S5 - Q2T0S5_BURTA

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Protein
Submitted name:

Phosphoribosylaminoimidazole carboxylase, ATPase subunit

Gene
purK, BTH_I0668
Organism
Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. metal ion binding Source: InterPro
  3. phosphoribosylaminoimidazole carboxylase activity Source: UniProtKB-EC

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseImported

Keywords - Biological processi

Purine biosynthesisSAAS annotations

Keywords - Ligandi

ATP-bindingSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

BioCyciBTHA271848:GJMY-668-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Phosphoribosylaminoimidazole carboxylase, ATPase subunitImported (EC:4.1.1.21Imported)
Gene namesi
Name:purKImported
Ordered Locus Names:BTH_I0668Imported
OrganismiBurkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301)Imported
Taxonomic identifieri271848 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
ProteomesiUP000001930: Chromosome I

Interactioni

Protein-protein interaction databases

STRINGi271848.BTH_I0668.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4IZOX-ray1.85A1-398[»]
ProteinModelPortaliQ2T0S5.

Family & Domainsi

Sequence similaritiesi

Contains ATP-grasp domain.SAAS annotations

Phylogenomic databases

eggNOGiCOG0026.
HOGENOMiHOG000034029.
KOiK01589.
OMAiDCILEGW.
OrthoDBiEOG6QZMX7.

Family and domain databases

Gene3Di3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
InterProiIPR005875. AIR_COase_ATPase-su.
IPR011761. ATP-grasp.
IPR003135. ATP-grasp_carboxylate-amine.
IPR013816. ATP_grasp_subdomain_2.
IPR016185. PreATP-grasp_dom.
IPR011054. Rudment_hybrid_motif.
[Graphical view]
PfamiPF02222. ATP-grasp. 1 hit.
[Graphical view]
SUPFAMiSSF51246. SSF51246. 1 hit.
SSF52440. SSF52440. 1 hit.
TIGRFAMsiTIGR01161. purK. 1 hit.
PROSITEiPS50975. ATP_GRASP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2T0S5-1 [UniParc]FASTAAdd to Basket

« Hide

MTALPNPNSP ILPGAWLGMV GGGQLGRMFC FAAQAMGYRV AVLDPDPTSP    50
AGAVADKHLR AAYDDEAALA ELAQLCDAVS TEFENVPAAS LDFLAQSTFV 100
APAGRCVAIA QDRIAEKRFI AASGVPVAPH VVIESAAQLA ALADADLAAV 150
LPGILKTARL GYDGKGQVRV ATAQEARDAY GSLGGVPCVL EKRLPLKYEV 200
SALIARGANG ASAVFPLAQN THHGGILSLS VVPAPAASDA LVRDAQQAAA 250
RIADSLDYVG VLCVEFFVLE DGSLVANEMA PRPHNSGHYT VDACETSQFE 300
QQVRAMTRLP LGSTRQHSPA AMLNVLGDVW FASGASGEPV TPPWDQVAAM 350
PTARLHLYGK EEARVGRKMG HVNFTAATLD EAVAGATACA RLLRIPLD 398
Length:398
Mass (Da):41,463
Last modified:January 24, 2006 - v1
Checksum:i245ED46131BE00EF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000086 Genomic DNA. Translation: ABC37891.1.
RefSeqiYP_441224.1. NC_007651.1.

Genome annotation databases

EnsemblBacteriaiABC37891; ABC37891; BTH_I0668.
GeneIDi3848781.
KEGGibte:BTH_I0668.
PATRICi19304101. VBIBurTha36512_3367.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000086 Genomic DNA. Translation: ABC37891.1 .
RefSeqi YP_441224.1. NC_007651.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4IZO X-ray 1.85 A 1-398 [» ]
ProteinModelPortali Q2T0S5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 271848.BTH_I0668.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABC37891 ; ABC37891 ; BTH_I0668 .
GeneIDi 3848781.
KEGGi bte:BTH_I0668.
PATRICi 19304101. VBIBurTha36512_3367.

Phylogenomic databases

eggNOGi COG0026.
HOGENOMi HOG000034029.
KOi K01589.
OMAi DCILEGW.
OrthoDBi EOG6QZMX7.

Enzyme and pathway databases

BioCyci BTHA271848:GJMY-668-MONOMER.

Family and domain databases

Gene3Di 3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
InterProi IPR005875. AIR_COase_ATPase-su.
IPR011761. ATP-grasp.
IPR003135. ATP-grasp_carboxylate-amine.
IPR013816. ATP_grasp_subdomain_2.
IPR016185. PreATP-grasp_dom.
IPR011054. Rudment_hybrid_motif.
[Graphical view ]
Pfami PF02222. ATP-grasp. 1 hit.
[Graphical view ]
SUPFAMi SSF51246. SSF51246. 1 hit.
SSF52440. SSF52440. 1 hit.
TIGRFAMsi TIGR01161. purK. 1 hit.
PROSITEi PS50975. ATP_GRASP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Bacterial genome adaptation to niches: divergence of the potential virulence genes in three Burkholderia species of different survival strategies."
    Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C., DeShazer D.
    BMC Genomics 6:174-174(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: E264 / ATCC 700388 / DSM 13276 / CIP 106301.
  2. "Crystal structure of kinase Phosphoribosylaminoimidazole carboxylase, ATPase subunit from Burkholderia thailandensis."
    SSGCID, Abendroth J., Lorimer D., Edwards T.E.
    Submitted (JAN-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS).

Entry informationi

Entry nameiQ2T0S5_BURTA
AccessioniPrimary (citable) accession number: Q2T0S5
Entry historyi
Integrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: May 14, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome

External Data

Dasty 3

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