Q2T0S5 (Q2T0S5_BURTA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Phosphoribosylaminoimidazole carboxylase, ATPase subunit EMBL ABC37891.1
EC=4.1.1.21 EMBL ABC37891.1

Gene names

Name:	purK EMBL ABC37891.1
Ordered Locus Names:	BTH_I0668

Organism

Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301) [Complete proteome] [HAMAP] EMBL ABC37891.1

Taxonomic identifier

271848 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group › Burkholderia thailandensis

Protein attributes

Sequence length	398 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Contains 1 ATP-grasp domain. SAAS SAAS003135

Ontologies

Keywords
Biological process	Purine biosynthesis SAAS SAAS003135
Ligand	ATP-binding SAAS SAAS003135 Nucleotide-binding
Molecular function	Lyase EMBL ABC37891.1
Technical term	3D-structure PDB 4IZO Complete proteome
Gene Ontology (GO)
Biological_process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW metal ion binding Inferred from electronic annotation. Source: InterPro phosphoribosylaminoimidazole carboxylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2T0S5 [UniParc]. Last modified January 24, 2006. Version 1. Checksum: 245ED46131BE00EF	FASTA	398	41,463
	10 20 30 40 50 60 MTALPNPNSP ILPGAWLGMV GGGQLGRMFC FAAQAMGYRV AVLDPDPTSP AGAVADKHLR 70 80 90 100 110 120 AAYDDEAALA ELAQLCDAVS TEFENVPAAS LDFLAQSTFV APAGRCVAIA QDRIAEKRFI 130 140 150 160 170 180 AASGVPVAPH VVIESAAQLA ALADADLAAV LPGILKTARL GYDGKGQVRV ATAQEARDAY 190 200 210 220 230 240 GSLGGVPCVL EKRLPLKYEV SALIARGANG ASAVFPLAQN THHGGILSLS VVPAPAASDA 250 260 270 280 290 300 LVRDAQQAAA RIADSLDYVG VLCVEFFVLE DGSLVANEMA PRPHNSGHYT VDACETSQFE 310 320 330 340 350 360 QQVRAMTRLP LGSTRQHSPA AMLNVLGDVW FASGASGEPV TPPWDQVAAM PTARLHLYGK 370 380 390 EEARVGRKMG HVNFTAATLD EAVAGATACA RLLRIPLD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Bacterial genome adaptation to niches: divergence of the potential virulence genes in three Burkholderia species of different survival strategies." Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C., DeShazer D. BMC Genomics 6:174-174(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: E264 / ATCC 700388 / DSM 13276 / CIP 106301.
[2]	"Crystal structure of kinase Phosphoribosylaminoimidazole carboxylase, ATPase subunit from Burkholderia thailandensis." SSGCID, Abendroth J., Lorimer D., Edwards T.E. Submitted (JAN-2013) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

CP000086 Genomic DNA. Translation: ABC37891.1.

RefSeq

YP_441224.1. NC_007651.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4IZO	X-ray	1.85	A	1-398	[»]

ProteinModelPortal

Q2T0S5.

ModBase

Search...

Protein-protein interaction databases

STRING

271848.BTH_I0668.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

ABC37891; ABC37891; BTH_I0668.

GeneID

3848781.

KEGG

bte:BTH_I0668.

PATRIC

19304101. VBIBurTha36512_3367.

Organism-specific databases

CMR

Search...

Phylogenomic databases

eggNOG

COG0026.

HOGENOM

HOG000034029.

KO

K01589.

OMA

GRKMGHF.

ProtClustDB

PRK06019.

Enzyme and pathway databases

BioCyc

BTHA271848:GJMY-668-MONOMER.

Family and domain databases

Gene3D

3.30.470.20. 1 hit.
3.40.50.20. 1 hit.

InterPro

IPR005875. AIR_COase_ATPase-su.
IPR011761. ATP-grasp.
IPR003135. ATP-grasp_carboxylate-amine.
IPR013816. ATP_grasp_subdomain_2.
IPR016185. PreATP-grasp_dom.
IPR011054. Rudment_hybrid_motif.
[Graphical view]

Pfam

PF02222. ATP-grasp. 1 hit.
[Graphical view]

SUPFAM

SSF52440. PreATP-grasp-like. 1 hit.
SSF51246. Rudmnt_hyb_motif. 1 hit.

TIGRFAMs

TIGR01161. purK. 1 hit.

PROSITE

PS50975. ATP_GRASP. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q2T0S5_BURTA

Accession

Primary (citable) accession number: Q2T0S5

Entry history

Integrated into UniProtKB/TrEMBL:	January 24, 2006
Last sequence update:	January 24, 2006
Last modified:	May 1, 2013
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)